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      • SCOPUSKCI등재

        Correlation of morphological variants of the soft palate and Need's ratio in normal individuals: A digital cephalometric study

        Verma, Pradhuman,Verma, Kanika Gupta,Kumaraswam, Kikkeri Lakshminarayana,Basavaraju, Suman,Sachdeva, Suresh K.,Juneja, Suruchi Korean Academy of Oral and Maxillofacial Radiology 2014 Imaging Science in Dentistry Vol.44 No.3

        Purpose: The present study was aimed to investigate the variation of soft palate morphology in different age and gender groups. The correlations of radiographic velar length (VL), velar width (VW), pharyngeal depth (PD), and Need's ratio with soft palate variants were also studied in the North Indian subpopulation. Materials and Methods: The study sample consisted of 300 subjects aged between 15 and 45 (mean: 31.32) years. The velar morphology on lateral cephalograms was examined and grouped into six types. The results obtained were subjected to a statistical analysis to find the correlation between variants of the soft palate with gender and different age groups. Results: The most frequent type of soft palate was leaf shaped (48.7%), and the least common was crook shaped (3.0%) among both the genders and various age groups, showing a significant correlation. The mean VL, VW, and PD values were significantly higher in males and significantly correlated with the types of soft palate. A significant correlation was observed between the mean VL, VW, PD, and Need's ratio with various age groups, showing an inconsistent pattern with an increase in age. The types of soft palate, gender, and Need's ratio were also significantly correlated, with an overall higher mean value of the Need's ratio among female subjects and the S-shaped soft palate. Conclusion: The knowledge of a varied spectrum of velar morphology and the variants of the soft palate help in a better understanding of the velopharyngeal closure and craniofacial anomalies.

      • KCI등재

        Correlation of morphological variants of the soft palate and Need’s ratio in normal individuals: A digital cephalometric study

        Pradhuman Verma,Kanika Gupta Verma,Kikkeri Lakshminarayana Kumaraswam,Suman Basavaraju,Suresh K. Sachdeva,Suruchi Juneja 대한영상치의학회 2014 Imaging Science in Dentistry Vol.44 No.3

        Purpose: The present study was aimed to investigate the variation of soft palate morphology in different age and gender groups. The correlations of radiographic velar length (VL), velar width (VW), pharyngeal depth (PD), and Need’s ratio with soft palate variants were also studied in the North Indian subpopulation. Materials and Methods: The study sample consisted of 300 subjects aged between 15 and 45 (mean: 31.32) years. The velar morphology on lateral cephalograms was examined and grouped into six types. The results obtained were subjected to a statistical analysis to find the correlation between variants of the soft palate with gender and different age groups. Results: The most frequent type of soft palate was leaf shaped (48.7%), and the least common was crook shaped (3.0%) among both the genders and various age groups, showing a significant correlation. The mean VL, VW, and PD values were significantly higher in males and significantly correlated with the types of soft palate. A significant correlation was observed between the mean VL, VW, PD, and Need’s ratio with various age groups, showing an inconsistent pattern with an increase in age. The types of soft palate, gender, and Need’s ratio were also significantly correlated, with an overall higher mean value of the Need’s ratio among female subjects and the S-shaped soft palate. Conclusion: The knowledge of a varied spectrum of velar morphology and the variants of the soft palate help in a better understanding of the velopharyngeal closure and craniofacial anomalies.

      • KCI등재

        Anticataract activity of rhamnocitrin isolated from Bauhinia variegata stem bark

        Bodakhe, Surendra H.,Ram, Alpana,Verma, Suruchi,Pandey, Devi Prasad 경희한의학연구센터 2012 Oriental Pharmacy and Experimental Medicine Vol.12 No.3

        A cataract is any clouding or opaque area in the eye's natural lens, which is normally crystal clear, is the leading cause of blindness worldwide. It accounts for approximately 42% of all blindness. Approximately 25% of the population over 65 and about 50% over 80 age has serious loss of vision because of cataract. Most cataracts progress and eventually hamper vision. Multiple mechanisms have been implicated in the development of cataract. But the exact pathogenesis which leads to opacification is not clearly known. Oxidative damage to the lens has been recognized as the initiating event in the pathogenesis of cataracts. In cataract, the oxidation-antioxidant equilibrium shift more towards oxidative stress. Accordingly, antioxidants could prove potential anticataract agents. Rhamnocitrin, a flavonoid, possess strong antioxidant effects; can be used effectively to manage the cataract. Therefore, anticataract activity of rhamnocitrin (10, 20, 40 and 80 ${\mu}g$), isolated from Bauhinia variegata (Leguminosae) stem bark, was studied in ovine and chick embryo lens model. It showed a significant protection against cloudiness in lenses induced by hydrogen peroxide and hydrocortisone in a dose dependent manner. The findings suggest that rhamnocitrin possess significant anticataract activity and act most likely due to its antioxidant property.

      • KCI등재후보

        Potential of some traditionally used edible plants for prevention and cure of diabesity associated comorbidities

        Vikas Kumar,Ajit Kumar Thakur,Suruchi Verma,Vaishali Yadav,Shyam Sunder Chatterjee 셀메드 세포교정의약학회 2015 셀메드 (CellMed) Vol.5 No.2

        Medicinal uses of edible and other plants for prevention and cure of obesity and overweight associated metabolic and mental health problems have since long been known to scholars and practitioners of Ayurvedic and other traditionally known system of medicine. Modernized versions of numerous edible plant derived formulations mentioned in ancient Ayurvedic texts are at present some of the most popular, or best selling, herbal remedies in India and numerous other countries suffering from double burden of diseases caused by malnutrition and obesity. Preclinical and clinical information now available on edible plants and their bioactive constituents justify traditionally known medicinal uses of products derived from them for prevention and cure of obesity associated type-2 diabetes, psychopathologies and other health problems. Such information now available on a few edible Ayurvedic plants and their formulations and suggesting that their stress response regulating effects are involved in their broad spectrums of bioactivity profiles are summarized in this communication. Implications of recent physiological and pharmacological observations made with numerous phytochemicals isolated from edible plants for better understanding of traditionally known medicinal uses of herbal remedies are also pointed out.

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