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Sunil Kumar Jaiswal,Ch.V.Rao 경희대학교 융합한의과학연구소 2016 Oriental Pharmacy and Experimental Medicine Vol.31 No.4
Basella alba L. (Basellaceae) is an Indian spinach (English) which have extensively used in constipation, urticaria, diuretic, demulcent and antiulcers. This study was aimed to evaluate the standardized fractions with kaempferol from ethyl acetate extract of Basella alba leaves as gastroprotective, in vivo antioxidant and antisecretory activities in ulcerated rats. In this work the standardized fractions with kaempferol from ethyl acetate extract i.e. bioactive fraction of Basella alba leaves (BFBA) at a doses of 50, 100 and 200 mg/kg/b.w was administered orally bis in die for the treatment of acute ulcer induced by ethanol, aspirin, cold restraint stress and pylorus ligation. The in vivo antioxidant enzymes estimation were carried out in cold restraint stress induced ulcer whereas, gastric secretion and mucosal parameters were estimated in pylorus ligation induced ulcer models. BFBA produced significant inhibition of the gastric lesions induced by ethanol (22.82–66.30 %), aspirin (33.16–64.79 %), cold restraint stress (14.55–70.89 %) and pylorus ligation (32.89–69.73 %) respectively as compared to ulcerated control groups. The levels of antioxidant enzymes such as lipid peroxidase and superoxide dismutase were decreases, whereas increases in catalase and glutathione peroxidase values were observed. The results of our studied shown that BFBA possess a significant antiulcer and antisecretory activities probably by reducing the secretion of acids and offering antioxidant protection against oxidative stress-induced gastric damage and by enhancing glycoprotein secretion.
Vikas Kumar Singh,Priti Upadhyay,Pallavi Sinha,Ashish Kumar Mall,Ranjith K. Ellur,Atul Singh,Sanjay K.Jaiswal,Sunil Biradar,S. Ramakrishna,R.M. Sundaram,Ilyas Ahmed,B. C. Viraktamath,C. Kole,Sukhpal S 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.1
A total of six TGMS (thermosensitive genic male sterile lines) and nine pollinator lines were subjected to molecular characterization using 48 genome-wide SSR (simple sequence repeat) markers. Cluster analysis revealed clear differentiation among the TGMS lines according to their source of origin. The SSR-based genetic distance between the hybrids of the parental lines ranged from 0.36to 0.79 suggesting a high degree of genetic divergence. Among a set of 54 hybrids generated using parental lines, 32 showed better parent heterosis (+21.7%) while 19 showed mid-parent heterosis (+15.0%). For the trait yield per plant genetic distance (GD) was negatively correlated with F1 performance (r = -0.202), mid-parent heterosis (r = -0.325*; P < 0.05), and better parent heterosis (r = -0.261), while it was positively correlated with specific combining ability (r = 0.042). Based on the grouped genetic distance (GGD),the hybrid combinations were divided into four groups. The GGD showed linear correlation with hybrid performance within the group (GGD = 40 - 50: r = -0.07; GGD = 70 - 80: r = 0.32). This information can be utilized in the development of higher yielding,two-line rice hybrids through selection of intermediately diverse parental lines using GGD.
Singh, Vikas Kumar,Upadhyay, Priti,Sinha, Pallavi,Mall, Ashish Kumar,Ellur, Ranjith K.,Singh, Atul,Jaiswal, Sanjay K.,Biradar, Sunil,Ramakrishna, S.,Sundaram, R.M.,Ahmed, Ilyas,Viraktamath, B.C.,Kole, 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.1
A total of six TGMS (thermosensitive genic male sterile lines) and nine pollinator lines were subjected to molecular characterization using 48 genome-wide SSR (simple sequence repeat) markers. Cluster analysis revealed clear differentiation among the TGMS lines according to their source of origin. The SSR-based genetic distance between the hybrids of the parental lines ranged from 0.36 to 0.79 suggesting a high degree of genetic divergence. Among a set of 54 hybrids generated using parental lines, 32 showed better parent heterosis (+21.7%) while 19 showed mid-parent heterosis (+15.0%). For the trait yield per plant genetic distance (GD) was negatively correlated with $F_1$ performance (r = -0.202), mid-parent heterosis (r = $-0.325^*$; P < 0.05), and better parent heterosis (r = -0.261), while it was positively correlated with specific combining ability (r = 0.042). Based on the grouped genetic distance (GGD), the hybrid combinations were divided into four groups. The GGD showed linear correlation with hybrid performance within the group (GGD = 40 - 50: r = -0.07; GGD = 70 - 80: r = 0.32). This information can be utilized in the development of higher yielding, two-line rice hybrids through selection of intermediately diverse parental lines using GGD.