양주 노고산(老姑山) 독재동(篤才洞)의 장소성과 역사문화경관 해석

노재현 ( Jae Hyun Rho ),김화옥 ( Hwa Ok Kim ),이정한 ( Jung Han Lee ),박주성 ( Joo Sung Park ) 한국전통조경학회 2015 한국전통조경학회지 Vol.33 No.1

본 연구는 경기도 양주시 장흥면 삼하리 독재동 바위글씨와 노고산의 장소성에 주목하여, 이곳의 경관 및 장소특질을 고찰하고 바위글씨에 담긴 경관의미를 추론함으로써 노고산과 독재동 계곡의 역사문화경관적 함의를 밝히고자 한 것으로 연구 결과는 다음과 같다. 삼각산은 조선왕조 6백년 도읍지의 주산(主山)이며 오악(五嶽)을 이루는 중앙의 성산(聖山)으로, 노고산은 삼봉산(三峰山)즉 삼각산의 우람한 세봉우리를 향배하는 의미공간으로서 그 장소성이 획득된다. 더불어 노고산은 조선의 정기를 상징하는 삼각산을 가장 완벽하게 조망할 수 있는 ‘망삼각산(望三角山)’의 절대 시점장이다. 독재동 계곡에 산포(散布)된 다수의 바위글씨는 미수 허목의『고양산수기』의 내용을 현현(顯現)하기 위한 행위이자 경물로 재생산된 산물이다. 그리고 추사 필적의 몽재(夢齋)는 중의적(衆意的) 표현이 읽혀지는 바위글씨로, 먼저 글자 그대로의 뜻인 ‘꿈꾸는 집’ 이지만 내면적 의미는 “한낮 몽상(夢想)도 바탕을 깊이 헤아려 보면 정당성이 확보된다.”는 의미로 ‘몽재거사’로 알려진 성재(性齋) 허전(許傳)의 『몽재집(夢齋集)』서(序)의 내용으로 보아 성재의 독재동 거주와 관련된 징표로 추정된다. 또한 몽재라 쓴 바위 하단의 갑자(甲子)·경오(庚午)·무술(戊戌)·갑인(甲寅) 등의 간지(干支)는 추사와의 교유관계가 있는 1804년 5월생 유생(儒生)의 사주팔자로 판단된다. 노고산과 독재동 계곡은 삼각산을 조망하는 장소일 뿐 아니라 송월재·성재 등 미수의 학통을 계승한 기호지역의 남인학자의 공통된 장구지소로써의 응집력을 보여준다. 또한 이곳에 각자(刻字)된 추사체와 미수체(전서체) 바위글씨는 우리나라 서예사의 큰 흐름을 함축적으로 보여준다는 측면에서도 매우 의미 깊은 역사문화경관이다. This study was focused on the placeness of Nogosan Dokjae-dong and rock inscription located in Jangheung-myeon, Yangju-si, Gyeonggi-do. The purpose was to reveal the implication of Nogosan and Dokjae-dong Valley in terms of Historic cultural landscape by considering the characteristics of the place and its landscape, and inferring the significance of the letters engraved on the rock. The result is as follows.10)Samgaksan is one of the five famous mountains in Korea. It is the sacred mountain that stands behind the capital city of the Joseon Dynasty that lasted for 600 years. On the other hand, the placeness of Nogosan is significant since it was the place where people used to bow low to the three great summits of Samgaksan. Furthermore, Nogosan was the perfect place to view Samgaksan that represented the Joseon spirit.Many letters were engraved on the rocks around Dokjae-dong Valley by Misu(眉수) Heo Mok(許穆) as part of his memories to describe his experience in the mountain and became a scenery. Chusa(秋史) Kim Jung-Hee(金正喜) also engraved letters of ``Mongjae`` on the rock that contains a double meaning. Literally, it means ‘a dreaming house’ However, it also implies that even just a daydream is significant in a way. These letters are presumed to be the signs that are related to Sung-Jae(性齋) Heo Jeon(許傳)’s experience in Dokjae-dong since the letters were part of his famous book title. Below these two letters, Chusa also engraved letters that describe the sexagenary cycle including the year of the rat, horse, dog, and tiger. They are regarded as the letters that describe the fate of Chusa’s friend, a scholar born in May 1804. Nogosan and Dongjae-dong Valley are very significant in terms of historic cultural landscape as a viewpoint to see Samgaksan; and a place that cherishes the traces of Misu and shows common values and cohesiveness of well-known scholars of the Joseon Dynasty including Song Wol-Jae(松月齋) and Sung-Jae as a of Gihonamin(畿湖南人). The engraved letters of Chusa and Misu also implicitly demonstrates the major trends of Korea’s calligraphy history.

제초제 MCPP에 의한 화학적 화상

김은경 ( Eun Kyung Kim ),김혜성 ( Hei Sung Kim ),박영민 ( Young Min Park ),김형옥 ( Hyung Ok Kim ),이준영 ( Jun Young Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.10

MCPP (2-(4-chloro-2-methyl phenoxy) propionic acid) is a phenoxy herbicide found in many household weed killers and lawn fertilizers. Some of the phenoxy acids, salts, and esters are moderately irritating to skin, eyes, and respiratory and gastrointestinal linings. In a few individuals, local depigmentation has apparently resulted from protracted dermal contact with phenoxy compounds. Although acute irritant contact dermatitis induced by herbicides is common, chemical burns induced by herbicides have been reported infrequently in the literature. Here we describe a chemical burn in a 25 year old female after sitting on a lawn that had been sprayed with MCPP 3 days earlier. This case illustrates potential hazards of the herbicide on the lawn of a public park. (Korean J Dermatol 2011;49(10):936∼939)

Application of CCPM to Construction Project

김영,이영대,김옥수,김성환,박혁,Kim Young,Lee Young-Dae,Kim Ok-Su,Kim Sung-Hwan,Park Hyeok Korean Institute of Construction Engineering and M 2003 건설관리 : 한국건설관리학회 학회지 Vol.4 No.3

The Theory of Constraints (TOC) is an approach and a philosophy that is used to develop specific management techniques. It was first popularized by the novel, The Coal, that applied the principles to operations management. Since 1997 it has found application in two areas within project management The first application is scheduling of a sing1e project to reduce project duration and simplify project control. there is a further application to allocate resources that are shared by concurrent project. It is the objective of this paper to explore the fundamentals of critical chain and to pursue an application of critical chain method to construction project by a case study. 제약이론은 특정한 관리기술을 개발하는데 사용되는 접근방법이며, 철학이다. 운영관리상에 적용되었던 소설 "The Goal"에 의해서 처음으로 널리 보급되었다. 1997이후로 프로젝트관리의 두 가지 영역에서 적용되어 왔으며, 그 첫 번째 적용은 단일프로젝트에 대한 공기단축과 프로젝트 통제관리의 간소화를 위한 공정관리분야이며, 두 번째 적용은 동시에 수행되는 여러 프로젝트에 의해서 공유되는 자원의 효과적 관리이다. 이 논문은 프로젝트 관리에 적용된 제약이론인 애로사슬(Critical chain)의 원리에 대해서 연구하고, 국내의 건설프로젝트에 적용하는 것을 목적으로 한다.

GIS 를 이용한 산불 진화용 저수탱크 적지 분석에 관한 연구

이기철(Gi Chul Yi),김승환(Seung Hwan Kim),남정칠(Jung Chil Nam),박승범(Sung Burm Park),강영조(Young Jo Kang),옥진아(Jin A Ok) 한국지리정보학회 1998 한국지리정보학회지 Vol.1 No.2

이 논문의 주요 목적은 지리정보체계의 지도모델링 기법을 이용하여 소규모 산림의 산불 진화용 저수 탱크의 적지 분석에 있다. 부산광역시 서구에 위치한 암남 도시자연공원을 대상으로 산불진화 모델에 필요한 산불 진화 시설, 지형 등의 수치 지도 데이터베이스를 만들었다. 암남공원에 현재 설치되어 있는 산불 진화 시설에 근거해 조기진화가 가능한 지역과 산림의 산불 진화 효과를 밝히기 위해 지리정보체계를 이용한 서술적 지도모델링 기법을 적용해 현재의 저수 탱크 시 The objective of this paper is to develop a cartographic model for water tank suitability for small forest fire extinction using GIS. Various digital maps were created using CAD & GIS for Amnam urban park. which is located in Seogu, Pusan city. The park h

공동주택 주차장의 축적먼지 중 미량원소성분 분석과 오염원 평가

배건호(Gun Ho Bae),정철수(Cheol Su Jung),박규태(Kyu Tae Park),이명숙(Myoung Sook Lee),신동찬(Dong Chan Shin),김용혜(Yong Hye Kim),윤민혜(Min Hye Yoon),한영진(Young Jin Han),최혁(Hyuek Choi),백성옥(Sung Ok Baek) 大韓環境工學會 2011 대한환경공학회지 Vol.33 No.10

공동주택 주차장의 먼지오염실태를 연구하기 위하여 2010년 3월말에서 6월초까지 대구지역 공동주택 36곳의 지상주차장(36지점)과 지하주차장(36지점)을 대상으로 채취한 총 72개의 시료를 100 μm 이하로 체거름하고 산추출한 후 ICP로 14개원소를 분석하였다. 농축계수를 이용한 미량원소성분의 발생원 평가결과는 지상주차장과 지하주차장 모두 Fe, K, Mg, Mn, Na, V의 성분은 자연적인 발생원에 의한 영향을 받고 있는 반면에 Cd, Cr, Cu, Ni, Pb, Zn의 성분은 인위적인 발생원에 의한 영향을 받고 있는 것으로 나타났다. 한편 Ca은 지상주차장의 경우에는 자연적인 발생원의 영향을 받았고, 지하주차장의 경우에는 인위적인 발생원의 영향을 받은 것으로 나타났다. 미량원소성분의 농도분석 결과는 자연적인 발생원과 관련된 성분이 인위적인 발생원과 관련된 성분보다 매우 높은 농도를 보였다. 인위적인 발생원성분의 기여도는 지하주차장이 지상주차장보다 높았으며, 미량원소성분의 평균농도 또한 지하주차장이 지상주차장보다 높았다. 오염지수를 이용한 중금속성분의 오염도를 평가한결과는 지하주차장이 지상주차장보다 5.5배정도 높게 오염된 것으로 나타났다. 미량원소성분간의 상관성 분석결과는 지상주차장이 지하주차장에 비해 유의한 상관성을 나타내는 항목이 많았으며, 특히 자연적 발생원 성분간 유의한 상관성이 더욱 크게 나타났다. 또한 유해 중금속성분과 지하주차장의 영향인자간의 상관성을 분석한 결과는 주차대수(공간)가 적은 지점이 큰 지점보다, 환기장치를 가동하지 않은 지점이 가동한 지점보다, 그리고 최근 도색년도와 청소일이 오래된 지점이 상대적으로 유해중금속을 많이 함유하고 있었다. In order to investigate the degree of apartment parking lot dust contamination, total 72 samples of parking lot dust (36 from ground parking lots and 36 from the underground parking lots) were collected in Daegu city from the end of March to the early June 2010. The dust samples were sieved below 100 μm, and analysed by ICP for 14 elements after an acid extraction. Results obtained from the source assessment of trace element using enrichment factor showed that Fe, K, Mg, Mn, Na and V were influenced by natural sources, while Cd, Cr, Cu, Ni, Pb and Zn were influenced by anthropogenic sources in both the ground parking lot and the underground parking lot. And results showed that Ca were influenced by natural sources in the ground parking lot, but influenced by anthropogenic sources in the underground parking lot. The measured values were remarkably higher in components from natural sources than in components from anthropogenic sources. Underground parking lot dust was more affected by anthropogenic sources and contaminated compared with the ground parking lot dust. Pollution index of heavy metals revealed that underground parking lot dust was 5.5 times more contaminated with heavy metal components than the ground parking lot dust. The results of correlation analysis among trace elements indicated that components in the ground parking lot were more correlated than those in the underground parking lot, and especially more correlated with natural sources-natural sources. Analysis for correlations between components and influencing factors in the underground parking lot showed that concentrations of heavy metals were higher with smaller number of parking spaces and no ventilation system, and older apartments in last paint and cleaning had relatively higher contents of heavy metals than those of recently painted and cleaned.

Monitoring the status of T-cell activation in a microfluidic system

Park, Joo Young,Kim, Hyun Ok,Kim, Kyun-Do,Kim, Sung Kyu,Lee, Sang Kyou,Jung, Hyungil Royal Society of Chemistry 2011 The Analyst Vol.136 No.13

<P>Leukocyte adhesion to the endothelium through surface molecules such as E-selectin and intercellular adhesion molecule-1 (ICAM-1) is a critical cellular event reflecting the physiological status of both cell types. Here we present a microfluidic system that can not only easily monitor the interaction between leukocytes and endothelial cells under physiological conditions, but also screen drug candidates for potential modulation of this interaction. Shear stress, which is an important factor for the binding of activated T cells to tumor necrosis factor-alpha (TNF-α)-treated human umbilical vein endothelial cells (HUVECs), was easily controlled by adjusting the flow rate in the microfluidic system. Whole blood of patients with systemic lupus erythematosus (SLE) who have auto-reactive T cells were infused into the activated HUVECs which subsequently showed a higher level of binding compared to a control blood sample from a person without SLE. When these autoreactive T cells were treated with immunosuppressors tacrolimus and cyclosporin A, the binding of the T cells to HUVECs was dramatically decreased. Therefore, this microfluidic system is capable of differentiating the physiological status of T cells or endothelial cells representing different disease conditions, as well as being useful for the identification of novel reagents that modulate the functions of leukocytes or endothelial cells.</P> <P>Graphic Abstract</P><P>The physiological status representing different disease conditions can be identified with a microfluidic system which monitors the interaction between leukocytes and endothelial cells by adjusting shear stress. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1an15038c'> </P>

Evaluation of the Diagnostic and Therapeutic Effects on Tumor Cells by Using Anti - AFP Monoclonal Abs

Park, Tae Kyu,Kang, Shin Sung,Bang, Ok Sun,Cho, Dong Tek 한국유전학회 1988 Genes & Genomics Vol.10 No.4

By non-competitive enzyme-linked immunosorbent assay using anti-alpha-fetoprotein (AFP) monoclonal antibodies (MAbs), it was confirmed that screening of serum AFP level is essential in diagnosis of the hepatocellular carcinoma. By indirect immunofluorescence technique, anti-AFP MAbs were found to react with the surface of hepatoma cells (70%) and MCF-7 breast carcinoma cells (45%), but not with ME-180 cervic carcinoma cells. The purified anti-AFP MAbs were coupled with ricin toxin A-chain to form immunotoxin, whose effectiveness in in vitro killing of target cells was evaluated by cytotoxic assay. The results showed that this immunotoxin was specifically cytotoxic to hepatocellular carcinoma cells.

Immune-enhancing effects of <i>Portulaca oleracea</i> L.- based complex extract in cyclophosphamide-induced splenocytes and immunosuppressed rats

Park, Young Mi,Lee, Hak Yong,Kang, Yang Gyu,Park, Sang Hoon,Lee, Bong Gun,Park, Yeon Ju,Oh, Hong Geun,Moon, Dae In,Kim, Young Pill,Park, Deuk Seon,Lee, Hyang Man,Kim, Ok jin,Yang, Hye-Jeong,Kim, Min J CARFAX PUBLISHING CO 2019 FOOD AND AGRICULTURAL IMMUNOLOGY Vol.30 No.1

A leaf methanolic extract of Wercklea insignis attenuates the lipopolysaccharide-induced inflammatory response by blocking the NF-κB signaling pathway in RAW 264.7 macrophages.

Park, Ji-Won,Kwon, Ok-Kyoung,Jang, Ha-young,Jeong, Hyeok,Oh, Sei-Ryang,Lee, Hyeong-Kyu,Han, Sang-Bae,Ahn, Kyung-Seop Kluwer Academic/Plenum Publishers 2012 INFLAMMATION Vol.35 No.1

<P>The biological activity of Wercklea insignis (WI) in inflammation and the underlying mechanisms of action of extracts of this plant are largely unknown. In the present study, we investigated the effects of a WI methanolic extract on lipopolysaccharide-stimulated inflammation in the mouse macrophage cell line, RAW 264.7. A WI methanolic extract significantly inhibited NO, PGE(2), IL-6, IL-1β, and TNF-α production in LPS-stimulated RAW 264.7 cells. Expression of iNOS, COX-2, IL-6, IL-1β, and TNF-α were suppressed by the extract at both the mRNA and protein levels in lipopolysaccharide (LPS)-stimulated cells. Additionally, the attenuation of inflammatory responses in RAW 264.7 cells by the WI extract was closely associated with suppression of phosphorylation of mitogen-activated protein kinase (MAPK) molecules, including ERK, JNK1/2, and p38 MAPK and translocation of the nuclear factor (NF)-κB p65 subunit into the nucleus. The effect of WI extract was investigated against carrageenan-induced paw edema in female (20-25 g). Our results collectively indicate that the WI extract inhibits LPS-induced inflammatory responses by blocking the NF-κB signaling pathway in macrophages, supporting use of the extract as a therapeutic anti-inflammatory treatment.</P>

A Murine Model of Toluene Diisocyanate-induced Contact Hypersensitivity

Ok Hee Chai,Sung Gil Park,Jang Sihn Sohn,Seung Soo Hwang,Guang Zhao Li,Eui-Hyeog Han,Hyoung Tae Kim,Moo Sam Lee,Hurn-Ku Lee,Yong Chul Lee,Chang Ho So 대한면역학회 2002 Immune Network Vol.2 No.3