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Yun, Yeo-Tae,Chung, Chong-Tae,Lee, Young-Ju,Na, Han-Jung,Lee, Jae-Chul,Lee, Sun-Gye,Lee, Kwang-Won,Yoon, Young-Hwan,Kang, Ju-Won,Lee, Hyun-Sook,Lee, Jong-Yeol,Ahn, Sang-Nag Springer US 2016 Rice Vol.9 No.-
<P><B>Background</B></P><P>Improved eating quality is a major breeding target in <I>japonica</I> rice due to market demand. Consequently, quantitative trait loci (QTL) for glossiness of cooked rice and amylose content associated with eating quality have received much research focus because of their importance in rice quality.</P><P><B>Results</B></P><P>In this study, QTL associated with 12 grain quality traits were identified using 96 introgression lines (IL) of rice developed from an interspecific cross between the Korean elite <I>O. sativa japonica</I> cultivar ‘Hwaseong’ and <I>O. rufipogon</I> over 7 years. QTL analyses indicated that QTL <I>qDTH6</I> for heading date, detected on chromosome 6 is associated with variance in grain traits. Most QTLs detected in this study clustered near the <I>qDTH6</I> locus on chromosome 6, suggesting the effect of <I>qDTH6. O. rufipogon</I> alleles negatively affected grain quality traits except for a few QTLs, including <I>qGCR9</I> for glossiness of cooked rice on chromosome 9. To characterize the effect of the <I>O. rufipogon</I> locus harboring <I>qGCR9,</I> four lines with a single but different <I>O. rufipogon</I> segment near <I>qGCR9</I> were compared to Hwaseong. Three lines (<I>O. rufipopgon</I> ILs) having <I>O. rufipogon</I> segment between RM242 and RM245 in common showed higher glossiness of cooked rice than Hwaseong and the other line (Hwaseong IL), indicating that <I>qGCR9</I> is located in the 3.4-Mb region between RM242 and RM245. Higher glossiness of cooked rice conferred by the <I>O. rufipogon</I> allele might be associated with protein content considering that three lines had lower protein content than Hwaseong (<I>P</I> < 0.1). These three <I>O. rufipogon</I> ILs showed higher yield than Hwaseong and Hwaseong IL due to increase in spikelets per panicle and grain weight indicating the linkage of <I>qGCR9</I> and yield component QTLs.</P><P><B>Conclusion</B></P><P>The <I>qGCR9</I> locus is of particular interest because of its independence from other undesirable grain quality traits in <I>O. rufipogon</I>. SSR markers linked to <I>qGCR9</I> can be used to develop high-quality <I>japonica</I> lines and offer a starting point for map-based cloning of genes underlying this trait. To our knowledge, this is the first report to map a beneficial QTL for glossiness of cooked rice from a wild rice, <I>O. rufipogon</I>.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1186/s12284-016-0135-0) contains supplementary material, which is available to authorized users.</P>
Yun Mi Jung,Kim Gunn Hee,Ko Sung-chul,Han Yun Jae,Kim Wooshik 대한마취통증의학회 2022 Anesthesia and pain medicine Vol.17 No.2
Background: Myasthenia gravis (MG) is an autoimmune disease, and early thymectomy is recommended. Since the introduction of video-assisted thoracoscopic surgery, the safety and effectiveness of carbon dioxide insufflation in the thoracic cavity (capnothorax) has been controversial. This study aimed to compare the safety and effectiveness of ventilation methods in bilateral video-assisted thoracoscopic extended thymectomy (BVET) with capnothorax.Methods: We retrospectively investigated the medical records of patients with MG who underwent BVET between August 2016 and January 2018. Patients were divided into two groups: group D (n = 26) for one-lung ventilation and group S (n = 28) for two-lung ventilation. We set nine anesthesia time points (T0–T8) and collected respiratory and hemodynamic variables, including arterial O2 index (PaO2/FiO2).Results: SpO2 at T1–T3 and T8 was significantly lower in group D than in group S. The FiO2 in group S was lower than that in group D at all time points. The number of PaO2/FiO2 ≤ 300 and PaO2/FiO2 ≤ 200 events was significantly higher in group D than in group S. Hemodynamic variables were not significantly different between the two groups at any time point. The duration of surgery and anesthesia was shorter in group S than in group D. Conclusions: This retrospective study suggests that anesthesia using two-lung ventilation during BVET with capnothorax is a safe and effective method to improve lung oxygenation and reduce anesthesia time.
Chul Yun,Tae-Sung Jang,Nae-Soo Cho,Byung-Keun Yoon,Woo-Hyen Kwon 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.5
This paper proposes a controller design method for suppressing the resonance generated in the slave motor in the middle and low speed operation range, according to the load and parameter differences between two motors, during parallel operation using the master and slave method that controls two surface permanent magnet synchronous motors connected in parallel by a single inverter. The proposed resonance suppression controller is directly obtained by analyzing the resonance characteristics, using the lead controller method. Therefore, it is possible to fundamentally reduce trial and error to set the controller gain. In addition, because the proposed resonance suppression controller was designed as a lead controller, the stability region of the system increased owing to the added zero point, making the system robust with respect to parametric variations. Simulations and experiments confirmed the usefulness of the proposed method and the system’s robustness with respect to parametric variations.
Sung Chul Yun,Mun Il Ahn 한국환경농학회 2009 한국환경농학회지 Vol.28 No.2
The increased CO2 and temperature (700 μmol·mol-1 CO2 and 30℃) was compared with ambient growth conditions (400 μmol·mol-1 CO2 and 25℃) in hot pepper. Gas exchange measurements, including net photosynthesis (Pnet) and stomatal conductance (g(s)), were taken according to treatment in fields of peppers grown in Suwon and Asan during 2008. The increased treatment Pnet by 35-45% throughout the season and was statistically significant in t-tests (p<0.001); however, it did not significantly affect g(s). In addition, the gas exchange parameters in sun and shade leaves were measured. The difference between the sun and shade leaves was much greater than that between the elevated and ambient treatments, especially at harvest. Four commercial cultivars of hot pepper, Chunhasangsa, Ryukang, Manitta, and Olympic, were also compared by ANOVA. Chunhasangsa had the highest Pnet, which decreased by 30% from the vegetative to the harvest stage. Based on a factorial design, the effect of the increased CO2 and temperature was assessed based on the temperature, CO2, and their interaction effects. Orthogonal contrasts showed that the effects of temperature on Pnet and g(s) were significant, whereas CO2 and their interactions were not.
Enhancement of Anticancer Effect through Photodynamic Therapy with High Oxygen Concentration
Yun-Ho Kim,Phil-Sang Chung,Sang Joon Lee,Jang-In Shin,Heejun Hwang,Jin-Chul Ahn 대한의생명과학회 2009 Biomedical Science Letters Vol.15 No.1
In photodynamic therapy (PDT), oxygen plays important role. Because of singlet oxygen which is produced by activated photosensitizer after laser irradiation of specific wavelength. The aim of this study is to find how oxygen concentration affects anticancer effect in PDT. Groups were divided into PDT with oxygen applied group and only PDT applied group. PDT with oxygen applied group supplied oxygen for 15 minute before laser irradiation. In vitro, CT-26 cell was incubated with various concentration of photofrin (50.0~0.05 ㎍/ml) and was irradiated with 632 ㎚ diode laser 6 hr after application of photofrin. The cell viability of two groups was assessed by MTT assay. In vivo, CT-26 cell line was transplanted into the subcutaneous tissue of BALB/c mouse. The anticancer effect of two groups was measured by tumor volume change. In vitro study, the cell viability was significantly decreased at 1.56~3.13 ㎍/ml in PDT with oxygen applied group. In vivo study, the PDT with oxygen applied group significantly higher reduction rate of tumor volume 7 days after PDT compared to PDT only group. The high oxygen concentration might enhance the anticancer effect of the photodynamic therapy.