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Suneetha Pentyala,K. Devi Sankar,P. Sharmila Bhanu,N. S. Sampath Kumar 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.1
Pre-communicating or A1 segment of anterior cerebral artery (A1ACA) hypoplasia can negotiate the anterior cerebral circulation. Not many studies have been examined the association of hypoplastic A1ACA and cerebral ischemic stroke (CIS). In this study the authors’ want to accomplish the relationship between hypoplastic A1ACA and outcomes among the patients with CIS in Andhra Pradesh population of India. Retrospective review of prospectively identified 201 adult patients with CIS from 2015 to 2017 was achieved. Patients underwent 3.0T intracranial magnetic resonance angiography were compared with clinical and radiological aspects between male and female cases of A1ACA hypoplasia with associated variations in the circle of Willis. The obtained data was statistically analysed using SPSS software version 16.0 for Windows and P-value <0.05 was considered as significant. Chi-square test was applied to find out the association between the sex and incidence of hypoplastic A1ACA. Sixty-four of 201 patients with A1ACA hypoplasia with no aplastic cases were recorded. It was found to be more in males than females and common on right than left side. Frequent neurological indications such as headache, dizziness, visual instability, nausea, weakness of extremities and seizure were noted and most cases were associated with CIS. Hypoplastic A1ACA often associated with ischemia of terminal branches of ipsilateral ACA which is compromised by the blood flow via contralateral ACA. In this study, though the CIS is not directly related to hypoplastic A1ACA, any alterations in A1 segment is a considerable risk factor of stroke.
Shama Panjwani,Suneetha B Manyam,Priscilla Rose Prasath 한국상담학회 2021 Journal of Asia Pacific counseling Vol.11 No.2
The purpose of this study was to examine the impact of various immigration statuses on the quality of life among Asian Indians in the United States. The 73 Asian Indians, born in India and residing in the U.S., who participated in the survey study, reported experiencing varied levels of quality of life depending on their immigration status. Mental health counselors working with immigrants, in particular, Asian Indian clients, will benefit from the findings that highlight the need for heightened awareness of immigration-related policies and its impact on their clients’ immigration statuses, mental health and overall acculturation process.
Naidu, C Kumaraswamy,Suneetha, Y Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
One of the most common cancer types faced by the women around the world is breast cancer. Among the several low, moderate and high penetrance genes conferring susceptibility to breast cancer, PTEN is one which is known to be mutated in many tumor types. In this study, we predicted and analyzed the impact of three deleterious coding non-synonymous single nucleotide polymorphisms rs121909218 (G129E), rs121909229 (R130Q) and rs57374291 (D107N) in the PTEN gene on the phenotype of breast tumors using computational tools SIFT, Polyphen-2, PROVEAN, MUPro, POPMusic and the GETAREA server.