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      • SCIESCOPUSKCI등재

        The Efficacy and Safety of 4-n-butylresorcinol 0.1% Cream for the Treatment of Melasma: A Randomized Controlled Split-face Trial

        ( Sun Young Huh ),( Jung Won Shin ),( Jung Im Na ),( Chang Hun Huh ),( Sang Woong Youn ),( Kyoung Chan Park ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.1

        Background: Melasma is a common acquired symmetrical hypermelanosis that occurs on sun-exposed areas, and it is frequently observed among women. Various treatment modalities have been tried, but none are completely satisfactory. 4-n-butylresorcinol, which is a resorcinol derivative that has an inhibitory effect on both tyrosinase and tyrosinase-related protein-1, was introduced in 1995 and it has received increasing attention as a new hypopigmenting agent. However, the hypopigmenting effect of 4-n-butylresorcinol in human subjects has only been shown in a few studies. Objective: The aim of this study was to investigate the hypopigmenting efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma. Methods: Twenty patients with melasma were enrolled to this randomized, double-blind, vehicle-controlled, split-face comparative study. The patients were instructed to apply 4-n-butylresorcinol 0.1% cream or vehicle to each side of the face twice daily for 8 weeks. Mexameter measurements were performed along with photography at baseline, 4 weeks and 8 weeks. Adverse events were observed and recorded throughout the study. Results: All the patients completed the study. Mexameter measurements demonstrated that the melanin index of the treated side showed a significant decrease when compared with that of the vehicle-treated side after 4 weeks (p=0.006) and after 8 weeks (p<0.0005). All the adverse reactions were mild and transient. Conclusion: 4-n-butylresorcinol 0.1% cream showed rapid efficacy and it was well tolerated when used for the treatment of melasma. (Ann Dermatol 22(1) 21∼25, 2010)

      • 흉추 후방접근법으로 완전 정복된 외상성 척추앞전위증 1예 : A case report

        황선철,김범태,이세영,임수빈,신원한 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        The thoracic spine is rigidly stabilized by the ribs, anterior and posterior longitudinal ligaments, and a sagittal orientation of the facet joints that resists axial rotation and horizontal translation. Thus, a significant force is required to cause a fracture and dislocation in the thoracic spine. A 32-year-old man was involved in a motor-vehicle accident and presented with complete paraplegia and spondyloptosis on the 8th thoracic vertebral segment. He also suffered with hypoxia and hypovolemic shock. Posterior reduction and fixation with pedicle screw was achieved with the anatomic alignment and rigid stability. This posterior technique for thoracic spondyloptosis is believed to be sufficient to make good alignment and solid fixation.

      • KCI등재후보

        Maypole Type 편조기의 Guide Track의 동적 모델링 및 해석

        정원지,김재량,최선준,김임선 한국공작기계학회 2003 한국생산제조학회지 Vol.12 No.4

        Braiding machines of maypole type complex guide tracks. It is not easy to speed up driers while carriers are moving at high speed. This paper presents a new design approach using dynamic analysis and modeling for moving carriers on the guided tracks. The proposed approach will be shown to be effective by using simulation tool, WORKING MODEL 2D^??, for high drivers on new models of braiding machines of maypole type.

      • 中高 蹴球選手의 傷害에 관한 調査 硏究

        金元天,李任仙,朴鏡實 진주여자전문대학 1992 論文集 Vol.15 No.-

        The purpose this study was to find the sports injuries of secondary school soccer players. 6 middle school and 6 high school team of soccer players were furnished data this investigation. All of them males and 13-19 years old. The subject were requested by questionary asked on the condition of illness, parts, situation. term, and hospital or other curative means. The result were as follow. 1. The most commonly part of injury in middle school player was 30cases of leg.(28.30%) The most commonly part of injury in high school player 27 cases ankle joint.(26.21%) 2. The most frequently sort of injury both in subject was bruises. 3. The cases of injury both middle school player and high school player was mostly one´s own carelessness.(each 41.52%, 41.75%) 4. The frequency of the injury during practice was 56cases of middle school player(52.83%) and 64 cases in high school player(62.14%). 5. The mcthod of common treatment was hospital. 6. The period of treatment was from a week to over 5 month, and common duration was less thin a month.(each 91.3%, 70.00%)

      • 소아에서 소뇌출혈을 동반한 털모양별세포종 1예

        황선철,김범태,이세영,임수빈,신원한 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Spontaneous intracranial hemorrage is rare in the childhood, which is usually caused by vascular anomalies, blood dyscrasia and trauma. A 15-year-old child presented with sudden headache while he was studying. The fretures of radiologic images suggested the cerebellar hematoma caused by the underlying lesion such as vascular malformation or cavernous hemangioma. The operation finding revealed that the hematoma was caused by a tumor, which adhered to the superior medullary velum of cerebellum. The pathology revealed it to be hemorrhagic pilocytic astrocytoma. The hemorrhagic pilocytic astrocytoma should be considered in the diagnosis of the lesion in cerebellar hematoma.

      • 跳躍選手의 特殊體力에 관한 硏究

        李任仙,金元天,朴鏡實 진주여자전문대학 1992 論文集 Vol.15 No.-

        This shudy is that the jumping decathlon for the effect of training had introduced by Derek Boosey was applied to relatively excellent athletes for improving the specific physical fitness of jumpers, and their record was measured, in case their materials will be compared, analyzed definitely, as follows ; 1) Jumper(Long Jumper, Triple, High Jumper, Pole Vault)in the excellent group in all the terms, especially. They are above-average in 2 hop step & jump, 2 hop 2 step & jump, 2 hop 2 step & 2 jump and so on, but they are below-average at run 4 hop & jump. Therefore, in all the items, there is p〈0.001 difference between two groups. 2) jumper, in the average athletes group, excel slightly in the 2 hop step & jump, 2 hop 2 step & jump, 2 hop 2 step & 2 jump. But they don't excel at most of all items there is p〈0.001 difference between two groups. In conclusion, our country (Korea) jumping athletes are inferior to those of the average world in the specific physical fitness. And the specific physical fitness is closely related to each item each other, because of the similarity of the specific physical fitness element. This element is very important requisite to improve the record of the jumping. In consideration of this result, if we make use of this fundamental mat on training, this materials will be helpful to improve the specific physical fitness of jumpers.

      • 성인에서 소뇌 중심부에 발생한 기형종 1예

        황선철,김범태,이세영,임수빈,신원한 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        The exact preoperative diagnosis in the cerebellar midline tumor is crucial to design the operative plan such as the extent of tumor resection, preservation of critical structures, and need to be shunt. We experienced a cystic tumor on the middle cerebellum, which were suspected as usual radiologic diagnoses but were revealed as rare entities in the pathology. A 40 year-old woman suffered from lasting headache and ataxia. In the radiologic finding, it was a huge cystic mass with a mural nodule. We took into consideration cerebellar tumor such as dermoid cyst, hemangioblatoma, or cystic astrocytoma. The pathologic diagnosis was the mature teratoma. We report a case of mature teratoma occured in the midline cerebellum and review it with pertinent literatures.

      • KCI등재

        상악 제1 및 제2소구치의 발치공간 폐쇄기전에 대한 3차원 유한요소 해석의 비교 연구

        고신애,임원희,박선형,전윤식 대한치과교정학회 2007 대한치과교정학회지 Vol.37 No.6

        교정 치료에서 발치공간 폐쇄는 치열을 이루는 모든 치아의 연속적인 이동으로 이루어지므로 그 기전은 복잡하다. 특히 전치부 치축을 적절히 유지하면서 구치부 고정원을 조절하는 과정은 정교함을 요하기 때문에 입체적 분석을 통한 치아이동 양상에 대한 이해가 필요하다. 지금까지의 유한요소 분석은 초기 응력분포를 관찰하여 치아 이동 양상을 예측해 보는데 그쳤지만 이러한 양상만으로 정확한 치아이동 결과를 추정하는 데에는 한계가 있었다. 따라서 본 연구에서는 3차원 유한요소 모델을 이용하여 상악 제1소구치 및 제2소구치 발치공간 폐쇄 시 전치부와 구치부의 입체적인 이동 양상을 단계별로 비교하여 그 기전을 규명하고자 하였다. 자연치의 크기 및 형태를 갖는 상악 치아들과 브라켓, 교정용 호선 및 치조골부를 3차원 레이저 스캐너로 스캐닝한 후 사면체 요소의 유한요소모델을 제작하였다. 0.017" x 0.025" 스테인레스 강 호선에 제작된 bull 루프 후방에 10˚의 gable bend를 부여하고 한 번에 2mm씩 12회 활성화시켜 발치공간을 폐쇄시켰다. 그 결과 제1소구치를 발치한 경우 제2소구치 발치에 비해 전치부의 후방 이동량이 많았으며 구치부의 전방 이동량은 더 적게 나타났다. 전치부에서는 제1, 2소구치 발치 모두 비슷한 미약한 정출을 동반하였고 치축의 변화량은 제1소구치 발치에서 더 크게 나타났다. 또한 제2소구치 발치 시 고정원의 협측 이동량이 더 크게 나타났다. Objective: The aim of this study was to compare the differences in closing extraction spaces between maxillary first premolar and second premolar extractions using 3-dimensional finite element analysis (FEA). Methods: Maxillary artificial teeth were selected according to Wheeler's dental anatomy. The size and shape of each tooth, bracket and archwire were made from captured real images by a 3D laser scanner and FEA was performed with a 10-noded tetrahedron. A 10˚ gable bend was placed behind the bull loop on a 0.017" x 0.025" archwire. The extraction space was then closed through 12 repeated activating processes for each 2mm of space. Results and Conclusions: The study demonstrated that the retraction of anterior teeth was less for the second premolar extraction than for the first premolar extraction. The anterior teeth showed a controlled tipping movement with slight extrusion, and the posterior teeth showed a mesial-in rotational movement. For the second premolar extraction, buccal movement of posterior teeth was highly increased.

      • KCI등재후보

        우리나라 일부 석면사업장의 석면폐 유병률

        백도명,백남원,최정근,손미아,임정기,이원진,문영한,박정선,최병순 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

        Asbestos industry has been in operation over 60 years in Korea. However, the prevalence of asbestosis has not been yet reported. With rapid turn-over of workers, previous cross-sectional studies of current workers on the job could not find cases with exposures long enough for the development of asbestosis. This study was done to evaluate asbestosis prevalence of those worksites with operation history of more than 20 years. In total, 139 workers from 5 worksites were examined. Asbestos industries covered in the study include 2 asbestos textile, 1 brake lining, and 2 ship repairing worksites. Chest x-ray was taken from all workers and read by two experts familiar with pneumoconiosis classification according to 1980 ILO guidelines. Those with findings compatible with asbestosis were further ckecked with high resolution computerized tomography (HRCT). Pulmonary function tests were done according to ATS guidelines, and occupational and previous medical history was taken through a standardized interview. Air-borne asbestos was measured according to NIOSH method 7400. The air-borne asbestos concentrations ranged from 0.2-1.3 f/cc for asbestos textile, from 0.7-1.0 f/cc for brake lining, and from 6.3-7.8 f/cc during asbestos removal at ship repairing worksite. Of the 139 workers 25 had abnormal chest radiographic findings, and 10 of them had findings compatible with pneumoconiosis. When work history and current asbestos measurements were accounted, 9 workers who had more than 10 years of asbestos exposure history showed chest radiographic findings of pneumoconiosis with Finally, 4 workers showed finding of pulmonary fibrosis and/or pleural thickening at HRCT, and 2 of them had restrictive lung function changes. The study results showed that, among 139 subjects, there were 4(3%) definite asbestosis cases confirmed with HRCT. The prevalence of probable asbestosis was 7% for 10-14 years of exposure, 13% for 15-19 years of exposure, and 23% for 20 or more years of exposure. The prevalence of compensable asbestosis with abnormal lung function was 4-6% for those with 15 or more years of exposure.

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