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Oh, Sumi,Lee, Chankyu,Kim, SungHwa,Choi, HyungSeok,Kim, Mi-Ja,Lee, JaeHwan Wiley (John WileySons) 2017 Journal of the American Oil Chemists' Society Vol.94 No.11
<P>Effects of deuteron (D+) and electron donors on the oxidative stability in linoleic acid-water model systems were evaluated by analyzing headspace oxygen content and headspace volatiles. Acetic acid-d and tetrakis(dimethylamino)ethylene (TDAE) were selected as a deuteron and an electron donor, respectively. Samples containing acetic acid-d had significantly lower headspace oxygen content than controls while those containing TDAE had significantly higher headspace oxygen content (p < 0.05). Combination of acetic acid-d and TDAE accelerated the consumption of headspace oxygen. Volatiles including t-2-heptenal, 2-octenal, or 2,4-octadienal had higher mass to charge ratio (m/z) of (molecular weight +1)/molecular weight in samples with deuterium oxide than in samples with deuterium free water. However, no significant difference was observed in the m/z ratio of (molecular weight +1)/molecular weight of those volatiles among samples with or without deuteron or electron donors. Also, lipid hydroperoxides with deuterium, were not found in samples containing deuterium oxide and acetic acid-d. Therefore, added acetic acid-d may not be involved on the formation of lipid hydroperoxides and volatiles directly.</P>
Oh, Sumi,Yi, Bo Ra,Park, Jung Woo,Kim, Mi-Ja,Lee, Jae Hwan The Korean Society for Applied Biological Chemistr 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.4
The effects of tween 20, one of neutral emulsifiers, on oxidative stability of corn oil were determined under a relative humidity (RH) range of 0-93 % at room temperature after 350 days of storage. The degree of oxidation was determined by headspace oxygen content and conjugated dienoic acids analyses. Moisture content and ${\alpha}$-tocopherol were also analyzed. The degree of lipid oxidation was significantly influenced by the concentration of tween 20 and relative humidity. Samples without addition of tween 20 showed the highest oxidative stability in 11 % RH, whereas oxidative stability was lowest at 93 % RH. Adding 0.5 and 1.0 % tween 20 increased the rate of lipid oxidation in a concentration dependent manner. Samples containing tween 20 had higher moisture content than those without an amphiphilic compound. Stability of ${\alpha}$-tocopherol was depending on the content of moisture and amphiphilic compounds in bulk oil.
NON-STATIONARY BIORTHOGONAL WAVELET SYSTEMS CONSTRUCTED FROM INTERPOLATORY SUBDIVISION SCHEMES
Sumi JANG,Hong Oh KIM,Yeon Ju LEE,Jungho YOON 한국산업응용수학회 2007 한국산업응용수학회 학술대회 논문집 Vol.3 No.2
Interpolatory non-stationary subdivision schemes reproducing a certain class of basis functions are used to present the refinable functions and the assocaited dual functions. It generalizes the known interpolatory refinable functions reproducing polynomials. The new refinable functions are based on exponential polynomials and the integer shifted Gaussian functions respectively. With these refinable functions at hand, we construct the orthogonal and biorghogonal wavelet system. Our ultimate future goal is to perform the associated mathematical analysis including regularity, stability, and vanishing moments as well.
CONSTRUCTION OF A NON-STATIONARY BIORTHOGONAL WAVELET SYSTEM USING A SUBDIVISION SCHEME
Sumi JANG,Jungho YOON,Hong Oh KIM 한국산업응용수학회 2007 한국산업응용수학회 학술대회 논문집 Vol.2 No.1
We present the 4-point Gaussian based non-stationary interpolatory subdivision scheme which approximates the given data in the span of translations for the Gaussian function with the parameter λ. Different choice for the parameter leads to a different set of masks. The sequence of the refinable functions converges to the refinable function for the 4-point Deslauriers-Dubuc scheme in L<SUP>p</SUP>(0 < p < ∞). Using the subdivision mask as the lowpass filter, we construct the non-stationary biorthogonal Multiresolution Analysis(MRA) which has the approximation order of 4. Then we derive the corresponding non-stationary biorthogonal wavelet system. The resulting scaling functions and the wavelets are symmetric and compactly supported.
CHARACTERIZATIONS OF GABOR FRAMES
Sumi JANG,Byeongseon JEONG,Hong Oh KIM 한국산업응용수학회 2009 한국산업응용수학회 학술대회 논문집 Vol.2009 No.5
For positive integers N, M ∈ N, let gn, ∈ L²(R) with supp(Dbgn) ∪ supp(Dbgn) ⊂ [0, M], where Dbg(t) := b<SUP>?1/2</SUP>g(t/b), b > 0 and n = 1, 2, ...,N. We give another set of necessary and sufficient conditions for the multiwindow Gabor system (GN; a, b) := {gn;k,l(t) := gn(t ? ka)e<SUP>2πilbt</SUP>}n=1,...,N; k,l∈Z and the corresponding Gabor system (GN; a, b) to form a pair of dual frames for the rational sampling ab = P/Q with P,Q ∈ N, in addition to the Zibulski-Zeevi and Janssen conditions. The conditions come from the back transform of Zibulski-Zeevi condition to the primal domain but are more informative for the applications. As an applications, we show that the Gabor system (GN; 1, 1) forms an orthonormal basis for L²(R) if and only if N = 1 and |g₁(t)| = ∑M?1m=0 xm+Em(t) a.e. where {Em m=0,...,M?1 forms Lebesgue measurable partition of the unit interval [0, 1). Our criterions provides a rich family of multiwindow dual Gabor frames and multiwindow tight Gabor frames for L²(R) for the particular choices of P, Q, N, M ∈ N.
Yun, Sumi,Kwak, Yoonjin,Nam, Soo Kyung,Seo, An Na,Oh, Heung-Kwon,Kim, Duck-Woo,Kang, Sung-Bum,Lee, Hye Seung Korean Cancer Association 2018 Cancer Research and Treatment Vol.50 No.4
<P><B>Purpose</B></P><P>Molecular treatments targeting epidermal growth factor receptors (EGFRs) are important strategies for advanced colorectal cancer (CRC). However, clinicopathologic implications of EGFRs and EGFR ligand signaling have not been fully evaluated. We evaluated the expression of EGFR ligands and correlation with their receptors, clinicopathologic factors, and patients’ survival with CRC.</P><P><B>Materials and Methods</B></P><P>The expression of EGFR ligands, including heparin binding epidermal growth factor-like growth factor (HBEGF), transforming growth factor (TGF), betacellulin, and epidermal growth factor (EGF), were evaluated in 331 consecutive CRC samples using mRNA <I>in situ</I> hybridization (ISH). We also evaluated the expression status of EGFR, human epidermal growth factor receptor 2 (HER2), HER3, and HER4 using immunohistochemistry and/or silver ISH.</P><P><B>Results</B></P><P>Unlike low incidences of <I>TGF</I> (38.1%), <I>betacellulin</I> (7.9%), and <I>EGF</I> (2.1%), <I>HBEGF</I> expression was noted in 62.2% of CRC samples. However, the expression of each EGFR ligand did not reveal significant correlations with survival. The combined analyses of EGFR ligands and EGFR expression indicated that the ligands‒/EGFR+ group showed a significant association with the worst disease-free survival (DFS; p=0.018) and overall survival (OS; p=0.005). It was also an independent, unfavorable prognostic factor for DFS (p=0.026) and OS (p=0.007). Additionally, HER4 nuclear expression, regardless of ligand expression, was an independent, favorable prognostic factor for DFS (p=0.034) and OS (p=0.049), by multivariate analysis.</P><P><B>Conclusion</B></P><P>Ligand-independent EGFR overexpression was suggested to have a significant prognostic impact; thus, the expression status of EGFR ligands, in addition to EGFR, might be necessary for predicting patients' outcome in CRC. </P>
Establishment of Reference Intervals of Cytokeratin 19 Fragment Antigen 21-1 in Korean Adults
Yoon Sumi,Lim Yong Kwan,Kim Hye Ryoun,Lee Mi-Kyung,Kweon Oh Joo 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.1
Cytokeratin 19 fragment antigen 21-1 (CYFRA 21-1) is useful for predicting and monitoring non-small cell lung cancer prognosis. We established reference intervals (RIs) of CYFRA 21-1 in Korean adults, including those older than 60 years. Data of 4,098 apparently healthy subjects (age range, 20–87 years) were analyzed after excluding those with a history of malignancy, high tumor marker concentrations (except CYFRA 21-1), and/or abnormal findings on a chest computed tomography scan through medical chart review. After removing two outliers, RIs of CYFRA 21-1 were determined using data of 4,096 subjects based on the non-parametric method (2.5th and 97.5th percentiles) according to CLSI guidelines EP28-A3c. The subjects were divided into two and four groups according to sex and age (20–40, 41–50, 51–60, and >60 years), respectively, and the median CYFRA 21-1 concentration was compared between the groups. The RI of CYFRA 21-1 was 0.66–3.84 ng/mL, applicable to both men and women. Regardless of sex, the CYFRA 21-1 concentration increased with age, suggesting that age-dependent RIs of CYFRA 21-1 should be applied. Rather than using a single RI provided by the manufacturer, the RI of CYFRA 21-1 should be continually verified and established in each clinical laboratory.