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      • KCI등재후보

        일본 '레즈비언 전후사' 다시 읽기: '성욕'이라는 관점의 결여에 관하여

        SUGIURA Ikuko 서울대학교 일본연구소 2014 일본비평 Vol.- No.11

        How has modern Japan presented the “female intimacy”? This paper sheds light on the existing historical descriptions and how its development does not necessarily reflect the “history of sexuality,” and argues that the history of lesbian movements after the 1970s must be recaptured from the perspective of “sexual desire.” In this paper, the “perspective of sexual desire” questions how the concept of “sexual desire,” which has been constructed in various ways since the Taisho period, had dealt with discourses on “female intimacy” and “a woman who loves a woman.” In Japan, the term “lesbian” spread widely in the late half of the 1960s, and in the 1970s a number of information on lesbianism was available through the media. A number of researches on the history of lesbians have been published, but none of them have analyzed it as a discourse that create both spheres and experiences of lesbians’ (and women’s) sexual desires. In other words, it can be said that, in Japan, “postwar history of sexuality” on lesbians has not yet been written. This paper first deals with the period from the 1910s to the 1960s during which a concept of “sexual desire” was imported before the advent of lesbianism in Japan, and, from the perspective of “sexual desire,” analyzes how modern Japan attached meanings toward “female intimacy” and “a woman who loves a woman.” Second, the paper briefly touches upon the discourse on lesbianism found in the magazines after the 1970s, and examines the contemporary significance of adopting the “perspective of sexual desire.”

      • SCOPUSKCI등재
      • SCIESCOPUSKCI등재

        The effects of bone density and crestal cortical bone thickness on micromotion and peri-implant bone strain distribution in an immediately loaded implant: a nonlinear finite element analysis

        Sugiura, Tsutomu,Yamamoto, Kazuhiko,Horita, Satoshi,Murakami, Kazuhiro,Tsutsumi, Sadami,Kirita, Tadaaki Korean Academy of Periodontology 2016 Journal of Periodontal & Implant Science Vol.46 No.3

        Purpose: This study investigated the effects of bone density and crestal cortical bone thickness at the implant-placement site on micromotion (relative displacement between the implant and bone) and the peri-implant bone strain distribution under immediate-loading conditions. Methods: A three-dimensional finite element model of the posterior mandible with an implant was constructed. Various bone parameters were simulated, including low or high cancellous bone density, low or high crestal cortical bone density, and crestal cortical bone thicknesses ranging from 0.5 to 2.5 mm. Delayed- and immediate-loading conditions were simulated. A buccolingual oblique load of 200 N was applied to the top of the abutment. Results: The maximum extent of micromotion was approximately $100{\mu}m$ in the low-density cancellous bone models, whereas it was under $30{\mu}m$ in the high-density cancellous bone models. Crestal cortical bone thickness significantly affected the maximum micromotion in the low-density cancellous bone models. The minimum principal strain in the peri-implant cortical bone was affected by the density of the crestal cortical bone and cancellous bone to the same degree for both delayed and immediate loading. In the low-density cancellous bone models under immediate loading, the minimum principal strain in the peri-implant cortical bone decreased with an increase in crestal cortical bone thickness. Conclusions: Cancellous bone density may be a critical factor for avoiding excessive micromotion in immediately loaded implants. Crestal cortical bone thickness significantly affected the maximum extent of micromotion and peri-implant bone strain in simulations of low-density cancellous bone under immediate loading.

      • SCIESCOPUSKCI등재

        Effects of implant tilting and the loading direction on the displacement and micromotion of immediately loaded implants: an in vitro experiment and finite element analysis

        Sugiura, Tsutomu,Yamamoto, Kazuhiko,Horita, Satoshi,Murakami, Kazuhiro,Tsutsumi, Sadami,Kirita, Tadaaki Korean Academy of Periodontology 2017 Journal of Periodontal & Implant Science Vol.47 No.4

        Purpose: The purpose of this study was to investigate the effects of implant tilting and the loading direction on the displacement and micromotion (relative displacement between the implant and bone) of immediately loaded implants by in vitro experiments and finite element analysis (FEA). Methods: Six artificial bone blocks were prepared. Six screw-type implants with a length of 10 mm and diameter of 4.3 mm were placed, with 3 positioned axially and 3 tilted. The tilted implants were $30^{\circ}$ distally inclined to the axial implants. Vertical and mesiodistal oblique ($45^{\circ}$ angle) loads of 200 N were applied to the top of the abutment, and the abutment displacement was recorded. Nonlinear finite element models simulating the in vitro experiment were constructed, and the abutment displacement and micromotion were calculated. The data on the abutment displacement from in vitro experiments and FEA were compared, and the validity of the finite element model was evaluated. Results: The abutment displacement was greater under oblique loading than under axial loading and greater for the tilted implants than for the axial implants. The in vitro and FEA results showed satisfactory consistency. The maximum micromotion was 2.8- to 4.1-fold higher under oblique loading than under vertical loading. The maximum micromotion values in the axial and tilted implants were very close under vertical loading. However, in the tilted implant model, the maximum micromotion was 38.7% less than in the axial implant model under oblique loading. The relationship between abutment displacement and micromotion varied according to the loading direction (vertical or oblique) as well as the implant insertion angle (axial or tilted). Conclusions: Tilted implants may have a lower maximum extent of micromotion than axial implants under mesiodistal oblique loading. The maximum micromotion values were strongly influenced by the loading direction. The maximum micromotion values did not reflect the abutment displacement values.

      • Role of anti-aging factor and reactive sulfur species in the pathogenesis of COPD

        ( Hisatoshi Sugiura ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

        Cellular senescence is observed in the lungs of patients with COPD and may contribute to the disease pathogenesis. Growth differentiation factor 11 (GDF11) belongs to the transforming growth factor β superfamily and was recently reported to be a circulating protein that may have rejuvenating effects in mice. We aimed to investigate the amounts of GDF11 in the plasma and the lungs of patients with COPD and elucidate the possible roles of GDF11 in cellular senescence. The plasma levels of GDF11 were investigated in two separate cohorts by western blotting. The localisation and expression of GDF11 in the lungs were investigated by immunohistochemistry and quantitative reverse transcription PCR, respectively. The effects of GDF11 on both cigarette smoke extract (CSE)-induced cellular senescence in vitro and on elastase-induced cellular senescence in vivo were investigated. The levels of plasma GDF11 in the COPD group were decreased compared with the control groups in the two independent cohorts. The levels of plasma GDF11 were significantly positively correlated with pulmonary function data. The mRNA expression of GDF11 in mesenchymal cells from the COPD group was decreased. Chronic exposure to CSE decreased the production of GDF11. Treatment with GDF11 significantly inhibited CSE-induced cellular senescence and upregulation of inflammatory mediators, partly through Smad2/3 signaling in vitro. Daily GDF11 treatment attenuated cellular senescence and airspace enlargement in an elastase-induced mouse model of emphysema. The decrease in GDF11 may be involved in the cellular senescence observed in COPD. Furthermore, oxidative stress is a major aetiological factor driving COPD. Recently recognised as potent antioxidants, reactive persulfide and polysulfide species are biosynthesised by cystathionine β-synthase and cystathionine γ-lyase. The production of reactive persulfide and polysulfide species in the lungs of patients with COPD remain unknown. So, we aimed to examine the production of reactive persulfides and polysulfides, such as glutathione persulfide (GSSH), cysteine persulfide (CysSSH) and glutathione trisulfide (GSSSH), in lung-resident cells and epithelial lining fluid (ELF) obtained from patients with mild to moderate COPD. Lung tissues, primary lung cells, ELF and sputum were obtained. The amounts of reactive persulfides and polysulfides in the cells and ELF were measured by liquid chromatography-tandem mass spectrometry with β-(4-hydroxyphenyl) ethyl iodoacetamide as a trapping agent for hydroper/polysulfides. The amounts of synthases in the lung tissues, sputum and primary cells were quantified. The amounts of GSSH, CysSSH and GSSSH were decreased in the lung cells and ELF from patients with COPD. The amounts of reactive persulfides and polysulfides in the lung cells had a positive correlation with the degree of airflow limitation. By contrast, the amounts of the synthases were increased in the lung tissues and sputum cells of patients with COPD. We have identified a decrease in reactive persulfide and polysulfide species in the lungs of patients with COPD. These data suggest that the newly detected antioxidants reactive persulfides and polysulfides could be associated with the redox balance in the lungs of patients with COPD.

      • KCI등재후보

        The Toyota-Mainichi Building in Nagoya

        Shigeki Sugiura,Toshihiko Kohno 한국강구조학회 2008 International Journal of Steel Structures Vol.8 No.2

        When designing a super high-rise building in cities that are constantly hit by earthquakes, it is necessary to fully consider the earthquake environment, in addition to the natural phenomenon of wind. We therefore propose what we think and understand regarding this concern.

      • Soft Tissue Bruise Injury by Blunt Impact in Human-Robot Interaction - Difference of Tolerance between Chest and Extremities

        Ryuji Sugiura,Tatsuo Fujikawa,Rie Nishikata,Tetsuya Nishimoto 제어로봇시스템학회 2019 제어로봇시스템학회 국제학술대회 논문집 Vol.2019 No.10

        To obtain information on the mechanical tolerance of soft tissue bruise injury caused by dynamic contact between human body parts and a robot, impact tests were conducted using anesthetized live pigs. A falling-weight impact tester was used to conduct tests on the chest and extremities by varying the mass and dropping height of the impactor. The subcutaneous tissues of the impacted parts were sampled, and internal bleeding, as a sign of bruising, was pathologically observed. The minimum value of transferred energy per unit area, categorized as a mechanical tolerance value for bruising, was found to be significantly smaller in the extremities as compared to the chest owing to structural differences between the two parts. These structural differences should be carefully considered for safe robot designs.

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