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- 저자 : Sudershan Bhatia (검색결과 1 건)
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Sagar C. Patel,Jonathan Frandsen,Sudershan Bhatia,David Gaffney 대한부인종양학회 2016 Journal of Gynecologic Oncology Vol.27 No.5
Objective: Evaluate the impact of radiotherapy on cause specific survival (CSS) and overallsurvival (OS) for stage (I–III) clear cell, mucinous, and endometriod ovarian cancer. Methods: We analyzed incidence, survival, and treatments from the Surveillance,Epidemiology, and End Results (SEER) Program from 2004 to 2011 for clear cell, mucinous,and endometriod histologies of the ovary for stages (I–III). We examined CSS and OS for allthree histologies combined and each histology with relation to the use of adjuvant radiationtherapy (RT). Survival analysis was calculated by Kaplan-Meier and log-rank analysis. Results: CSS was higher in individuals not receiving RT at 5 years (81% vs. 74%) and 10 years(74% vs. 65%, p=0.003). OS was higher in individuals not receiving RT at 5 years (76% vs. 73%) and 10 years (64% vs. 59%, p=0.039). Stage III patients receiving RT had a higher OS at5 years (54% vs. 44%) and 10 year intervals (36% vs. 30%, p=0.037). Stage III patients withmucinous histology receiving RT had a higher OS at 5 years (50% vs. 36%) and 10 years (45%vs. 26%, p=0.052). Conclusion: Those receiving RT had a lower CSS and OS at 5 and 10 years. However, subgroupanalysis revealed a benefit of RT in terms of OS for all stage III patients and for stage IIIpatients with mucinous histology.
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