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Clostridium perfringgens에 의한 송아지의 腸毒血症에 관한 硏究
Soung Kun CHO(曺性根),Jong Yung KIM(金鍾琰),Jung Moon PARK(朴政文) 한국예방수의학회 1990 예방수의학회지 Vol.14 No.3
Clostridium perfringens which are one of the major causative organism calf enterotoxemia were isolated from diarrheal faeces of calves web digestive diseases, and isolated Cl. perfringens were identified by biochemical test. and subsequently the susceptibility to antibiotics of Cl. perfringens isolated were investigated for selection of effective antimicrobial. The incidence of diarrheal in calves were appeared in 300 (17.6%) of examined 1,700 calves. The isolation of Cl. perfringens from diarrheal feces were 95 strains (31.7%) of 300 samples, and these were identified by biochemical test. The population of Cl. perfringens in faeces were ranged 10⁷⁻⁸/g in 34(35.8%) and 10²⁻⁶/g in 61(64.2%) of 95 samples in case of diarrheal feces, and 10¹⁻⁵/g in samples in case of health faeces. The toxin of isolated 40 strains were a]most neutralized by Cl. perfringens type A antitoxin but not by type B, C, D and E antitoxin. In antimicrobial drug susceptibility to isolated strains, all strains were highly susceptible to cephalthin, chloramphenicol and penicillin.
국내(國內) 돼지의 Clostridium perfringens type C 감염증에 관한 연구
예재길,박경윤,조성근,Yeh, Jae-gil,Park, Kyoung-yoon,Cho, Soung-kun 대한수의학회 1993 大韓獸醫學會誌 Vol.33 No.3
Thirteen strains of Clostridium perfringens were isolated from the pigs with hemorrhagic enteritis. The characteristics of the outbreaks, clinical signs and lesions were examined. The biochemical properties, type of toxin and susceptibility to antimicrobial agents of the isolates were investigated. The results could be summarized as follows ; 1. Almost of the pigs affected with hemorrhagic enteritis, 17 cases examined from 1989 to 1992, were piglets less than 7 day old. 2. The average mortality rate of piglet less than 7 day old affected with hemorragic and necrotic enteritis was 48.5%. 3. The clinical signs of pigs with hemorrhagic enteritis were depression, hemorrhagic diarrhea, anemia and dehydration. Necropsy of the infected pigs showed typical hemorrhage of upper intestine and necrosis of mucosal membrane. 4. The characteristic biochemical properties of the isolates were 2-band hemolysis, positive reaction of reverse CAMP test and formation of LV precipitate in egg yolk medium. 5. The toxin type of the 13 isolates, investigated by mouse inoculation test, was all type C strains of Clostridium perfringens. 6. In susceptibility test to antimicrobial agents, 13 isolates of Clostridium perfringens were highly sensitive to ampicillin, enrofloxacin(Baytril), cephalothin, penicillin and trimethoprim-sulfamethoxazole.