전남지역 논토양의 미생물상에 관한 연구 : 미생물 분포조사와 불완전 균류의 동정에 대하여 Distribution of the microflora and identification of the imperfect fungi

朴京洙,金鍾世,朴悅,盧永福 조선대학교 기초과학연구소 1985 自然科學硏究 Vol.8 No.1

전남지역 일원인 광주를 비롯한 8개 지역을 임의로 선정하여 1983년 10월 20일부터 11월 5일 사이에 논토양을 채취하였다. Plate dilution method로 각 지역별 작토층에 서식하고 있는 미생물 취락정도를 조사하고 사상균류만을 선정하여 불완전균류만을 분리동정하였다. monsporic culture로 얻은 순수 균주는 50균주로서 관련된 참고자료들에 의해 39균주를 동정하였으며 동정된 균주는 5속 8종이였다. 본 조사에 의해 밝혀진 미생물 분포정도와 동정된 균주 내력은 다음과 같다. 1. 전남지역 일원의 논토양에서 평균미생물 취락수는 세균이 19.5×10^6이고 방선균이 38.1×10^5이였다. 사상균은 42.5×10^3으로 나타났으며 B/F, B/A 및 A/F율은 각각 458.8, 5.1과 89.6이였다. 2. 전남지역 일원의 논토양에서 분리된 사상균 중 불완전균류 5속 8종을 동정하였으며, 동정된 균주는 다음과 같다. Trichoderma virides, Alternaria alternata, Cladosporium cladosporioides, Penicillium citrinum, Penicillium implication, Penicillium janthinellum, Aspergillus niger, Aspergillus clavatus이다. This investigation was conducted to find out microflora of the paddy soil in Chunnam. Eight paddy soil samples were collected from the different sites. By the dilution plate method, a total number of microorganism was recorded at the upper layer (0∼10cm in depth). The fungi were isolated at the dilution plate from paddy soil samples of eight selected sites. They were obtained after pure cultures with a total of 50 isolated strains. Among these, 39 isolated strains (8 species in 5 genera) were identified and 11 isolated strains were unidentified. The results were summarized as follows; 1. The mean numbers of microorganisms in collected paddy soil were 19.5×10^6 in bacteria (B), 38.1×10^5 in actinomycetes (A), and 42.5×10^3 in fungi (F) per gr paddy soil. The ratios of B/F, B/A and A/F were 458.8, 5.1 and 89.6 respectively. 2. 39 isllated strains (8 species in 5 genera) of imperfect fungi were identified as follows; Trichoderma virides, Alternaria alternata, Cladosporium cladosporioides, Penicillium citrinum, Penicillium implication, Penicillium janthinellum, Aspergillus niger, Aspergillus clavatus.

Newcastle병 면역에 대한 연구

박경수,김종세,노영복 조선대학교 기초과학연구소 1987 自然科學硏究 Vol.10 No.1

A study was conducted to determine whether the vaccination programs for the control of Newcastle Disease (ND) would affect the immune status of hens against the disease as a purpose of suggesting the distinguished vaccination programs. Fifteen poultry flocks were surveyed to investigate the level of serum antibody against ND virus and the programs used for the vaccination of hens. Alternatively, vaccination was carried out by the programs designed against ND virus in hens called Manina and investigated the level of HI titer every week, and surveyed the alternation of hematological occurrence following the vaccination programs. The obtained results were summarized as follows: 1. Vaccination history of the investigated 15 poultry flocks were not according by standard vaccination programs and immunization was carried out for random at every poultry farms. Killed and Live vaccin was used together in 7 groups and only Live vaccin was used in 6 groups, and only killed vaccin was used in groups. 2. HI titer of these was 140 in average by killed and live vaccin, and live vaccin was 126 in average. The former was shown higher HI titer. 3. The number of leucocytes was shown much increased hy the designed vaccination program, and 9525/㎣ was shown by 2nd vaccination (9weeks), and 1067O/㎣ was shown highest by 6th vaccination (25weeks). 4. HI titer was 240 by 2nd vaccination and it was continuous to increase. HI titer was 320 by 6th vaccination. The effects of the repeated vaccination were distinguished. 5. Serum globulin value was increased according to the vaccination program. The highest value ware 3.54㎎/㎗ and 3.54㎎/㎗ in 22 weeks and 23 weeks, each γ globulin value of these were 0.95㎎/㎗ and 0.99㎎/㎗.

흰쥐 복직근과 대흉근 근섬유 유형에 대한 조직화학적 연구

민병운,박경수,노영복 조선대학교 기초과학연구소 1989 自然科學硏究 Vol.12 No.1

포유동물인 흰쥐의 대흉근과 복직근에 대한 근섬유 특성 및 근섬유 유형별 빈도를 조사하기 위하여 1988년 7월 2일~1988년 10월7일 조직화학적 및 각종 효소조직화학적 염색을 시행하여 조사한 바 다음과 같은 결론을 얻었다. 1. H-E 염색에 의한 근섬유의 유형별 구분은 불 명확하였으나, PAS 염색에서는 양성 반응의 정도에 따라서 세가지 유형으로 구분되었다. 2. Reversed myosin-ATP ase 염색과 SDH염색에서는 TypeⅠ, Ⅱa, Ⅱb의 세가지 유형의 근섬유형이 구분되었다. 그러나 typeⅡ와 Ⅱb의 유형별 빈도는 SDH염색과 Reversed myosin-ATP ase 염색상 상당한 차이가 있는 것으로 관찰되었다. 3. 포유동물인 흰쥐의 복직근과 대흉근의 근 섬유형 구성비는 부위에 따라서 상당한 차이가 있었다. In order to study properties and individual proportions of muscle fiber types on the pectoralis major an rectus abdominis muscle of the rat, vertebrates, histological and each kinds of enzyme histochemical stain (were performed). The following results were obtained : 1. Differentiation of muscle fiber types was not evident in H & E stained specimen. However, three types of muscle fibers were evidently differentiated in PAS stained sections according to the degree of positivity. 2. Muscle fiber of three types (typeⅠ, Ⅱa and Ⅱb) were differentiated in reversed-ATP ase and SDH stain. However, there were considerable difference between SDH and reversed-ATP ase stain properties in proportion of typeⅡa and Ⅱb. 3. The constituent proportions of muscle fibers in rectus abdominis and pectoralis major muscle of the rat were remarkably different according to the portions.

속성 퇴비화에 관한 연구

임채규,박경수,김홍섭,노영복 조선대학교 기초과학연구소 1988 自然科學硏究 Vol.11 No.1

This experiment was conducted to fine out the rapid composting method and the effects microorganism agent. The results were summarilized as follows; 1. Each temperatures of every composts highest rised at the 5 days during the experiment composting. 2. Composting temperature of the more 60℃ was killed the harmful lavar and pathogenic microorganisms. 3. The lowest C/N ratio was No.2, among the each treatments. 4. C/N ratio of the each treatments were same results of the general compost C/N ratio. 5. The synthesized of these results were recognized the effects of microorganism agent and the each treatments were showed the more rapid composting then general compost.

A Case of Glomeruloid Hemangioma in a Patient with Multicentric Castleman`s Disease

Rho, Nark Kyoung,Lee, Eil Soo,Park, Sang Jin,Lee, Dong Youn The Korean Dermatological Association 2002 Annals of Dermatology Vol.14 No.4

Glomeruloid hemangioma is a histologically distinctive cutaneous angioma which is rarely described in patients with POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome and multicentric Castleman's disease. We report an additional case of glomeruloid hemangioma in a 30-year-old Korean woman with multicentric Castleman's disease showing features of POEMS syndrome. Histopathology revealed multiple dermal dilated vascular spaces composed of a conglomerate of capillaries, resulting in structures reminiscent of renal glomeruli. Periodic acid-Schiff-positive and diastase-resistant eosinophilic globules were found within the cytoplasm of vacuolated endothelial cells. The endothelial cells lining the capillary loops showed positive immunostaining for factor Ⅷ-related antigen and CD31.

Adamantyl Benzamide 유도체의 미백효과

백흥수 ( Heung Soo Baek ),안수미 ( Soo Mi Ahn ),우병영 ( Byoung Young Woo ),조영석 ( Young Seok Cho ),최수정 ( Soo Jeong Choi ),노호식 ( Ho Sik Rho ),변경희 ( Kyoung Hee Byoun ),신송석 ( Song Seok Shin ),박영호 ( Young Ho Park 대한화장품학회 2013 대한화장품학회지 Vol.39 No.2

Polyhydroxylated benzamide 유도체의 구조변화에 따른 미백효과의 상관관계를 고찰하였다. Adamantyl benzamide 유도체에서 B ring 부분의 치환기가 catechol (3,4-dihydroxyphenyl)인 경우 우수한 멜라닌 생성 저해활성을 보였으나, mono-hydroxyphenyl (3-OH 또는 4-OH)이거나 3,4-dimethoxyphenyl인 경우에 그 활성이 감소하거나 없어졌다. 따라서 catechol unit이 멜라닌 생성 저해에 중요한 인자임을 알 수 있었다. 그리고 A-ring부분의 2-OH의 존재여부는 활성에 큰 영향을 주지는 않았고, A-ring과 B-ring을 연결하는 탄소사슬의 길이 역시 멜라닌 생성저해에 큰 영향을 주는 요소는 아니었다. The structure activity relationship of polyhydroxylated benzamide derivatives for whitening effects was examined. The adamantyl benzamide derivatives with catechol (3,4-dihydroxyphenyl) of B-ring part showed good anti- melanogenesis activity, but the inhibitory activity of mono-hydroxyphenyl (3-OH or 4-OH) or 3,4-dimethoxyphenyl substituted derivatives was decreased or lost. Therefore the catechol unit was appeared to be the crucial factor for the inhibition of melanogenesis. And the existence of 2-OH of A-ring part had minor influence on the activity, the length of carbon chain between A-ring and B-ring was also not the major factor for the anti-melanogenesis activity.

피부 원발성 CD30 (Ki-1) 양성 림프구증식 질환 : 중간형 1예 보고 Report of a Borderline Case

노낙경,윤성재,박형석,김원석,이일수 대한피부과학회 2003 대한피부과학회지 Vol.41 No.6

Primary cutaneous CD3O positive large cell Iymphoma is a cutaneous T-cell Iymphoma with a favorable prognosis, which is characterized by solitary or localized skin lesions with a tendency of spontaneous regression and frequent relapses. On the basis of the morphologic and immunophenotypic similarities between the large atypical cells in Iymphomatoid papulosis and the neoplastic cells in primary cutaneous CD30 positive large cell Iymphoma as well as their favorable prognosis, these two diseases are now regarded to be in a spectrum of primary cutaneous CD3O positive Iymphoproliferative disorder. We present a borderline case of primary cutaneous CD3O positive Iymphoproliferative disorder which recurred on the anatomic site different to the primary lesions despite multiple-agent chemotherapy. (Korean J Dermatol 2003;41(6) : 826~829)

Two Cases of Plasma Cell Cheilitis Treated with Intralesional Injection of Corticosteroids

Rho, Nark-Kyoung,Youn, Seong-Jae,Park, Hyung-Seok,Lee, Eil-Soo 대한피부과학회 2003 Annals of Dermatology Vol.15 No.1

Plasma cell cheilitis is a rare inflammatory disorder which shows a dense, band-like infiltrate of plasma cells in the upper dermis, Although the histological picture is shard with other diseases of the lips, plasma cell cheilitis is not associated with any known dermatoses. Some authors have shown the effectiveness of topical or intralesional corticosteroids; however, there have been many reports describing poor therapeutic response to topical steroids. We describe two patients with plasma cell chielitis whose clinical condition responded rapidly to the intralesional injection of corticosteroids.

피부 조직검사로 진단된 CADASIL(Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) 1예

노낙경,최석진,이일수 대한피부과학회 2002 대한피부과학회지 Vol.40 No.9

CADASIL(cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is a rare genetic disease inherited in an autosomal dominant manner, which is characterized by migraine, strokes, mood disorders, and progressive cognitive disorders. With the aid of skin biopsy and electron microscopic examination, recently we have confirmed a diagnosis of CADASIL in a patient from neurology department. Although CADASIL does not present any cutaneous manifestations, dermatologists need to be aware of this rare neurologic disorder because characteristic electron microscopic findings on a skin biopsy specimen are diagnostic.

중형의 선천성 멜라닌세포성 모반에서 발생한 것으로 추정되는 악성 흑색종 1예

노낙경,최석진,이일수,이동윤 대한피부과학회 2002 대한피부과학회지 Vol.40 No.9

Congenital melanocytic nevi are usually classified as small, medium-sized, and large according to their size. Many authors suggest that the risk for the occurrence of malignant melanoma may roughly be proportional to the size of underlying congenital melanocytic nevus. However, the risk of melanoma in medium-sized congenital melanocytic nevi is a controversial subject and universal recommendations regarding the management of such lesions has not been made. We present a 62-year old man with a medium-sized congenital melanocytic nevus in which malignant melanoma developed.