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Assembly of the Superconducting Tokamak EAST
Weiyue Wu,Daming Gao,Jie Yu,Peide Weng,Songtao Wu 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III
EAST is a new machine, Experimental Advanced Superconducting Tokamak, being built in CASIPP. Steady-state operation is a main mission for this machine and the superconducting magnets were all poloidal field and toroidal field systems, constituting an engineering mission to establish the technology basis of chosen to be full superconducting Tokamak to investigate a future fusion device. The parameters of EAST are: the main radius is 1.7 m and the minor radius is 0.4 m, with a maximum toroidal magnetic field of 3.5 Tesla at the plasma center. The plasma current is 1 MA, the pulse length is 1000 s, elongation is about 1.6 . 2.0, and triangularity is about 0.4 . 0.6. The EAST device has a large number of components to be assembled at the main building since June 18, 2003. These include: support structure, cryostat, thermal shields, vacuum vessel, toroidal field magnets, poloidal field magnets, current leads and joints, cooling tubes and insulators, first wall and other auxiliary systems. In this device the required assembly should maintain gaps and insulation blocks between toroidal field magnets, thermal shields and vacuum vessel. It was required to meet the tolerances for accurate positioning of the components in the radial, toroidal, poloidal and vertical directions, to ensure that the machine satisfied the requirements and to minimize subsequent corrective operations. This paper presents a brief description of the device in terms of design, fabrication, testing and assembly.
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Wu, Menglin,Chen, Qiang,He, XiaoJun,Li, Ping,Fan, Wen,Yuan, SongTao,Park, Hyunjin IEEE 2018 IEEE Transactions on Biomedical Engineering Vol.65 No.1
<P>Objective: Accurate segmentation of neurosensory retinal detachment (NRD) associated subretinal fluid in spectral domain optical coherence tomography (SD-OCT) is vital for the assessment of central serous chorioretinopathy (CSC). A novel two-stage segmentation algorithm was proposed, guided by Enface fundus imaging. Methods: In the first stage, Enface fundus image was segmented using thickness map prior to detecting the fluid-associated abnormalities with diffuse boundaries. In the second stage, the locations of the abnormalities were used to restrict the spatial extent of the fluid region, and a fuzzy level set method with a spatial smoothness constraint was applied to subretinal fluid segmentation in the SD-OCT scans. Results: Experimental results from 31 retinal SD-OCT volumes with CSC demonstrate that our method can achieve a true positive volume fraction (TPVF), false positive volume fraction (FPVF), and positive predicative value (PPV) of 94.3%, 0.97%, and 93.6%, respectively, for NRD regions. Our approach can also discriminate NRD-associated subretinal fluid from subretinal pigment epithelium fluid associated with pigment epithelial detachment with a TPVF, FPVF, and PPV of 93.8%, 0.40%, and 90.5%, respectively. Conclusion: We report a fully automatic method for the segmentation of subretinal fluid. Significance: Our method shows the potential to improve clinical therapy for CSC.</P>
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Song, Tao,Yu, Wei,Wu, Shi-Xiu Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1
The outcomes of first-generation EGFR-TKIs (Gefitnib and Erlotinib) have shown great advantages over traditional treatment strategies in patients with non-small cell lung cancer (NSCLC), but unfortunately we have to face the situation that most patients still fail to respond in the long term despite initially good control. Up to now, the mechanism of acquired resistance to EGFR-TKIs has not been fully clarified. Herein, we sought to compile the available clinical reports in the hope to better understanding the subsequent treatment choices, particularly on whether restoring after a drug holiday or switching to another EGFR-TKI is the better option after failure of one kind of EGFR-TKI.
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