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Effects of high power pulsed microwave on the enhanced color and flavor of aged blueberry wine
Siyuan Liu,Shuangjian Li,Siyuan Li,Ying Wang,Linlin Fan,Jianzhong Zhou 한국식품과학회 2024 Food Science and Biotechnology Vol.33 No.1
A new method of high-power pulsed microwave (HPPM) was applied to accelerate the aging of blueberry wine. The color changes of blueberry wines during aging were investigated through Chemical Wine Age and CIE-LAB measurement. Results showed that the blueberry wines treated by HPPM at low frequencies (50 and 100 Hz) exhibited improved color characteristics with L* value reaching 47.04 at 100 Hz, an increased maturity of wine body, and a shortened chemical wine age from 90 days to 75 days. Moreover, the aroma changes determined by GC-MS showed that HPPM accelerated the formation of esters in blueberry wine, which were increased by 18.44% and 56.97% respectively under the conditions of 50 and 150 Hz. The formation of acid substances was reduced compared with the original wine, with contents of acetic acid, caproic acid, and octanoic acid of 29.46 µg/mL, 15.60 µg/mL, 17.74 µg/mL, respectively, displaying an enhanced wine flavor.
Genetic algorithm‐based content distribution strategy for F‐RAN architectures
Xujie Li,Ziya Wang,Ying Sun,Siyuan Zhou,Yanli Xu,Guoping Tan 한국전자통신연구원 2019 ETRI Journal Vol.41 No.3
Fog radio access network (F‐RAN) architectures provide markedly improved performance compared to conventional approaches. In this paper, an efficient genetic algorithm‐based content distribution scheme is proposed that improves the throughput and reduces the transmission delay of a F‐RAN. First, an F‐RAN system model is presented that includes a certain number of randomly distributed fog access points (F‐APs) that cache popular content from cloud and other sources. Second, the problem of efficient content distribution in F‐RANs is described. Third, the details of the proposed optimal genetic algorithm‐based content distribution scheme are presented. Finally, simulation results are presented that show the performance of the proposed algorithm rapidly approaches the optimal throughput. When compared with the performance of existing random and exhaustive algorithms, that of the proposed method is demonstrably superior.
Structural noise mitigation for viaduct box girder using acoustic modal contribution analysis
Liu Linya,Jialiang Qin,Yun-Lai Zhou,Rui Xi,Siyuan Peng 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.72 No.4
In high-speed railway (HSR) system, the structure-borne noise inside viaduct at low frequency has been extensively investigated for its mitigation as a research hotspot owing to its harm to the nearby residents. This study proposed a novel acoustic optimization method for declining the structure-borne noise in viaduct-like structures by separating the acoustic contribution of each structural component in the measured acoustic field. The structural vibration and related acoustic sourcing, propagation, and radiation characteristics for the viaduct box girder under passing vehicle loading are studied by incorporating Finite Element Method (FEM) with Modal Acoustic Vector (MAV) analysis. Based on the Modal Acoustic Transfer Vector (MATV), the structural vibration mode that contributes maximum to the structure-borne noise shall be hereinafter filtered for the acoustic radiation. With vibration mode shapes, the locations of maximum amplitudes for being ribbed to mitigate the structure-borne noise are then obtained, and the structure-borne noise mitigation performance shall be eventually analyzed regarding to the ribbing conduction. The results demonstrate that the structural vibration and structure-borne noise of the viaduct box girder mainly occupy both in the range within 100 Hz, and the dominant frequency bands both are [31.5, 80] Hz. The peak frequency for the structureborne noise of the viaduct box girder is mainly caused by 16th and 62th vibration modes; these two mode shapes mainly reflect the local vibration of the wing plate and top plate. By introducing web plate at the maximum amplitude of main mode shapes that contribute most to the acoustic modal contribution factors, the acoustic pressure peaks at the field-testing points are hereinafter obviously declined, this implies that the structure-borne noise mitigation performance is relatively promising for the viaduct.
The role of exosomal lncRNAs in cancer biology and clinical management
Zhang Wuwen,Wang Qinshi,Yang Yi,Zhou Siyuan,Zhang Ping,Feng Tongbao 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
Exosomes play a vital role in cell–cell communication within the cancer microenvironment. Exosomal long noncoding RNAs (lncRNAs) are important regulators in cancer development and are involved in multiple processes, including cancer cell proliferation, angiogenesis, metastasis, drug resistance, and immunomodulation. Changes in the levels of exosomal lncRNAs often appear with the occurrence and development of cancer. Therefore, exosomal lncRNAs can be used as biomarkers for cancer diagnosis and prognosis. Exosomal lncRNAs can also indicate the treatment response of patients receiving chemotherapy. Moreover, exosomal lncRNAs are potential therapeutic targets for cancer treatment. In this review, we summarize the role of exosomal lncRNAs in cancer biology as well as in clinical management. A more comprehensive and in-depth understanding of the role of exosomal lncRNAs in cancer may help us better understand the mechanism of cancer development and clinically manage cancer patients.
Jo, Hyeju,Choi, Minho,Sim, Jaeuk,Viji, Mayavan,Li, Siyuan,Lee, Young Hee,Kim, Youngsoo,Seo, Seung-Yong,Zhou, Yuanyuan,Lee, Kiho,Kim, Wun-Jae,Hong, Jin Tae,Lee, Heesoon,Jung, Jae-Kyung Pergamon Press 2017 Bioorganic & medicinal chemistry letters Vol.27 No.15
<P><B>Abstract</B></P> <P>We have disclosed our effort to develop caffeic acid derivatives as potent and non-toxic inhibitors of α-MSH-stimulated melanogenesis to treat pigmentation disorders and skin medication including a cosmetic skin-whitening agent. The SAR studies revealed that cyclohexyl ester and secondary amide derivatives of caffeic acid showed significant inhibitory activities.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>