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        Long-term outcomes of surgery for oesophageal achalasia

        Zi Qin Ng,Brendan Murphy,Simon Edmunds,Mark Whitby,Jih Huei Tan,Stephen Archer 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.1

        Background: Long-term patient-reported outcomes following surgery for achalasia are lacking in the literature. The aim of this study was to evaluate both short- and long-term outcomes of the surgical management of achalasia. Methods: A retrospective analysis was performed of all surgically managed achalasia cases from January 2004 to December 2017. Data collection included demographics, previous interventions, type of surgery performed, and postoperative outcomes. Long-term data collected by questionnaire included residual regurgitation, dysphagia, chest pain, heartburn, need for subsequent intervention, and overall satisfaction. Patients were divided into primary group (group P) and secondary group (group S) based on whether they had undergone a previous intervention. Results: Ninety-one patients (male : female = 43 : 49; group P : S = 66 : 25) underwent surgery for achalasia. The median follow-up was 107 months (32–172 months). Twenty-five patients (27.5%) had previous interventions. Eighty-nine (97.8%) underwent Heller cardiomyotomy; the procedure was laparoscopic in 86 cases (97%) and open in three patients (3.3%). Two patients underwent stapled cardiomyotomy. The postoperative complication rate was 4.4%, and no complications were serious. There was no significant difference in length of stay between the groups. Short-term followup showed that most residual symptoms were mild. During long-term follow-up, the residual symptoms were mainly mild and did not differ between the groups. Furthermore, 72.9% of patients were satisfied or very satisfied with their symptoms post-surgery. Conclusion: The peri-operative morbidity for the surgical management of achalasia is low and re-intervention is uncommon. Heartburn was not a major long-term sequela of myotomy. Though patients still experienced mild symptoms in the longer term, most were satisfied with their outcome.

      • KCI등재

        Long-term outcomes of surgery for oesophageal achalasia

        Zi Qin Ng,Brendan Murphy,Simon Edmunds,Mark Whitby,Jih Huei Tan,Stephen Archer 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.1

        Background: Long-term patient-reported outcomes following surgery for achalasia are lacking in the literature. The aim of this study was to evaluate both short- and long-term outcomes of the surgical management of achalasia. Methods: A retrospective analysis was performed of all surgically managed achalasia cases from January 2004 to December 2017. Data collection included demographics, previous interventions, type of surgery performed, and postoperative outcomes. Long-term data collected by questionnaire included residual regurgitation, dysphagia, chest pain, heartburn, need for subsequent intervention, and overall satisfaction. Patients were divided into primary group (group P) and secondary group (group S) based on whether they had undergone a previous intervention. Results: Ninety-one patients (male : female = 43 : 49; group P : S = 66 : 25) underwent surgery for achalasia. The median follow-up was 107 months (32–172 months). Twenty-five patients (27.5%) had previous interventions. Eighty-nine (97.8%) underwent Heller cardiomyotomy; the procedure was laparoscopic in 86 cases (97%) and open in three patients (3.3%). Two patients underwent stapled cardiomyotomy. The postoperative complication rate was 4.4%, and no complications were serious. There was no significant difference in length of stay between the groups. Short-term followup showed that most residual symptoms were mild. During long-term follow-up, the residual symptoms were mainly mild and did not differ between the groups. Furthermore, 72.9% of patients were satisfied or very satisfied with their symptoms post-surgery. Conclusion: The peri-operative morbidity for the surgical management of achalasia is low and re-intervention is uncommon. Heartburn was not a major long-term sequela of myotomy. Though patients still experienced mild symptoms in the longer term, most were satisfied with their outcome.

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        Multi-view Clustering by Spectral Structure Fusion and Novel Low-rank Approximation

        Yin Lon,Xiaobo Liu,Simon Murphy 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.3

        In multi-view subspace clustering, how to integrate the complementary information between perspectives to construct a unified representation is a critical problem. In the existing works, the unified representation is usually constructed in the original data space. However, when the data representation in each view is very diverse, the unified representation derived directly in the original data domain may lead to a huge information loss. To address this issue, different to the existing works, inspired by the latest revelation that the data across all perspectives have a very similar or close spectral block structure, we try to construct the unified representation in the spectral embedding domain. In this way, the complementary information across all perspectives can be fused into a unified representation with little information loss, since the spectral block structure from all views shares high consistency. In addition, to capture the global structure of data on each view with high accuracy and robustness both, we propose a novel low-rank approximation via the tight lower bound on the rank function. Finally, experimental results prove that, the proposed method has the effectiveness and robustness at the same time, compared with the state-of-art approaches.

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