Codon usage bias and evolutionary analyses of Zika virus genomes

Siddiq Ur Rahman,Yuanhui Mao,Shiheng Tao 한국유전학회 2017 Genes & Genomics Vol.39 No.8

Zika virus (ZIKV) is a member of the family Flaviviridae and contains a single-stranded RNA genome with positive-polarity. Like Dengue, Zika virus uses Aedes aegypti mosquito as a vector to infect human with a wide range of clinical signs, from asymptomatic to influenzalike syndrome. Despite significant progress in genomic analyses, how a viral relationship with two different hosts affect the overall fitness, constancy, and dodging of hosts immune system are elusive. Here we analyzed Zika virus codon-based evolution using eleven strains from different geographical locations. The overall codon usage was similar and slightly bias among all strains. An occurrence of A-ending in highly-preferred codons and analysis by various approaches strongly suggests that mutational bias is the main force shaping codon usage in this virus. However, natural selection and geographical realities cannot be ignored in marginal influence on codon usage. The viral genomes naturally favor Aedes aegypti over human host for tRNA pool in translation. Such findings will assist researchers in understanding elements contribute to viral adaptation and evolutionary setup with hosts.

5^th Generation Wireless Networks Security: Challenges and Solutions

Siddiq, Bashayer Ahmed Bin International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.6

In reason of the high capacity and low latency, the 5G wireless networks used nowadays in many of life applications such as: remote surgery and guiding vehicle. The high requirements of 5G networks makes it more vulnerable for security threats and attacks. This paper presents some challenges faced by 5G networks and presets some of the security solutions.

Extra-spinal sciatica and sciatica mimics: a scoping review

Siddiq, Md Abu Bakar,Clegg, Danny,Hasan, Suzon Al,Rasker, Johannes J The Korean Pain Society 2020 The Korean Journal of Pain Vol.33 No.4

Not all sciatica-like manifestations are of lumbar spine origin. Some of them are caused at points along the extra-spinal course of the sciatic nerve, making diagnosis difficult for the treating physician and delaying adequate treatment. While evaluating a patient with sciatica, straightforward diagnostic conclusions are impossible without first excluding sciatica mimics. Examples of benign extra-spinal sciatica are: piriformis syndrome, walletosis, quadratus lumborum myofascial pain syndrome, cluneal nerve disorder, and osteitis condensans ilii. In some cases, extra-spinal sciatica may have a catastrophic course when the sciatic nerve is involved in cyclical sciatica, or the piriformis muscle in piriformis pyomyositis. In addition to cases of sciatica with clear spinal or extra-spinal origin, some cases can be a product of both origins; the same could be true for pseudo-sciatica or sciatica mimics, we simply don't know how prevalent extra-spinal sciatica is among total sciatica cases. As treatment regimens differ for spinal, extra-spinal sciatica, and sciatica-mimics, their precise diagnosis will help physicians to make a targeted treatment plan. As published works regarding extra-spinal sciatica and sciatica mimics include only a few case reports and case series, and systematic reviews addressing them are hardly feasible at this stage, a scoping review in the field can be an eye-opener for the scientific community to do larger-scale prospective research.

Interventional Pain Management in Rheumatological Diseases - A Three Years Physiatric Experience in a Tertiary Medical College Hospital in Bangladesh

Siddiq, Md. Abu Bakar,Hasan, Suzon Al,Das, Gautam,Khan, Amin Uddin A. The Korean Pain Society 2011 The Korean Journal of Pain Vol.24 No.4

Background: Interventional pain management (IPM) is a branch of medical science that deals with management of painful medical conditions using specially equipped X-ray machines and anatomical landmarks. Interventional physiatry is a branch of physical medicine and rehabilitation that treats painful conditions through intervention in peripheral joints, the spine, and soft tissues. Methods: A cross-sectional study was conducted using three years of hospital records (2006 to 2008) from the Physical Medicine and Rehabilitation Department at Chittagong Medical College Hospital in Bangladesh, with a view toward highlighting current interventional pain practice in a tertiary medical college hospital. Result: The maximum amount of intervention was done in degenerative peripheral joint disorders (600, 46.0%), followed by inflammatory joint diseases (300, 23.0%), soft tissue rheumatism (300, 23.0%), and radicular or referred lower back conditions (100, 8.0%). Of the peripheral joints, the knee was the most common site of intervention. Motor stimulation-guided intralesional injection of methylprednisolone into the piriformis muscle was given in 10 cases of piriformis syndrome refractory to both oral medications and therapeutic exercises. Soft tissue rheumatism of unknown etiology was most common in the form of adhesive capsulitis (90, 64.3%), and is discussed separately. Epidural steroid injection was practiced for various causes of lumbar radiculopathy, with the exception of infective discitis. Conclusion: All procedures were performed using anatomical landmarks, as there were no facilities for the C-arm/diagnostic ultrasound required for accurate and safe intervention. A dedicated IPM setup should be a requirement in all PMR departments, to provide better pain management and to reduce the burden on other specialties.

Silver nanoparticles containing hybrid polymer microgels with tunable surface plasmon resonance and catalytic activity

Mohammad Siddiq,Muhammad Ajmal,Zahoor Hussain Farooqi 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.11

Multi-responsive poly(N-isoprpylacrlamide-methacrylic acid-acrylamide) [P(NIPAM-MAA-AAm)] copolymer microgel was prepared by free radical emulsion polymerization. Silver nanoparticles were fabricated inside the microgel network by in-situ reduction of silver nitrate. Swelling and deswelling behavior of the pure microgels was studied under various conditions of pH and temperature using dynamic light scattering. A red shift was observed in surface plasmon resonance wavelength of Ag nanoparticles with pH induced swelling of hybrid microgel. The catalytic activity of the hybrid system was investigated by monitoring the reduction of p-nitrophenol under different conditions of temperature and amount of catalysts. For this catalytic reaction a time delay of 8 to 10min was observed at room temperature,which was reduced to 2 min at high temperature due to swelling of microgels, which facilitated diffusion of reactants to catalyst surface and increased rate of reaction.

Original Articles : Interventional Pain Management in Rheumatological Diseases -A Three Years Physiatric Experience in a Tertiary Medical College Hospital in Bangladesh

( Md Abu Bakar Siddiq ),( Suzon Al Hasan ),( Gautam Das ),( Amin Uddin A Khan ) 대한통증학회 2011 The Korean Journal of Pain Vol.24 No.4

Background: Interventional pain management (IPM) is a branch of medical science that deals with management of painful medical conditions using specially equipped x-ray and anatomical landmarks. Interventional physiatry is a branch of Physical Medicine and Rehabilitation that treat painful conditions by intervention in peripheral joints, spine, and soft tissues. Methods: A cross - sectional study was conducted using three years hospital records (2006 to 2008) of Physical Medicine and Rehabilitation Department, Chittagong Medical College Hospital, Bangladesh with a view to highlight current interventional pain practice in a tertiary medical college hospital. Results: Maximum intervention was done in degenerative peripheral joint disorders (600, 46.0%) followed by inflammatory joint diseases (300, 23.0%), soft tissue rheumatism (300, 23.0%), and radicular or referred low back conditions (100, 8.0%). Knee was the most commonly intervent peripheral joint. Motor stimulation guided intralesional injection methylprednisolone into piriformis muscle was given in 10 cases of piriformis syndrome refractory to oral medications and therapeutic exercises. Soft tissue rheumatism of unknown etiology was most common in the form of adhesive capsulitis (90, 64.3%) and discussed separately. Epidural steroid was practiced in different causes of lumbar radiculopathy except infective discitis. Conclusions: All procedures were performed using anatomical landmark as there was no facilities for c-arm/diagnostic ultrasound required for accurate and safe intervention. Dedicated IPM set up is required in all PMR departments for better pain management and reduce burden on other specialities.

Interventional Pain Management in Rheumatological Diseases - A Three Years Physiatric Experience in a Tertiary Medical College Hospital in Bangladesh

Md Abu Bakar Siddiq,Suzon Al Hasan,Gautam Das,Amin Uddin A Khan 대한통증학회 2011 The Korean Journal of Pain Vol.24 No.4

Background:Interventional pain management (IPM) is a branch of medical science that deals with management of painful medical conditions using specially equipped x-ray and anatomical landmarks. Interventional physiatry is a branch of Physical Medicine and Rehabilitation that treat painful conditions by intervention in peripheral joints, spine, and soft tissues. Methods:A cross - sectional study was conducted using three years hospital records (2006 to 2008) of Physical Medicine and Rehabilitation Department, Chittagong Medical College Hospital, Bangladesh with a view to highlight current interventional pain practice in a tertiary medical college hospital. Results:Maximum intervention was done in degenerative peripheral joint disorders (600, 46.0%) followed by inflammatory joint diseases (300, 23.0%), soft tissue rheumatism (300, 23.0%), and radicular or referred low back conditions (100, 8.0%). Knee was the most commonly intervent peripheral joint. Motor stimulation guided intralesional injection methylprednisolone into piriformis muscle was given in 10 cases of piriformis syndrome refractory to oral medications and therapeutic exercises. Soft tissue rheumatism of unknown etiology was most common in the form of adhesive capsulitis (90, 64.3%) and discussed separately. Epidural steroid was practiced in different causes of lumbar radiculopathy except infective discitis. Conclusions:All procedures were performed using anatomical landmark as there was no facilities for c-arm/diagnostic ultrasound required for accurate and safe intervention. Dedicated IPM set up is required in all PMR departments for better pain management and reduce burden on other specialities. (Korean J Pain 2011; 24: 205-215)

Comparison of Home Automation System Using IPV-4 and IPV-6 Based On Mitigate Reconnaissance Attacks

Ali, Muhammad Shujat,Siddiq, Imran,Faisal, Abdullah,Awan, Muhammad Zubair International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.2

This research is designed to help and offer hold up to complete the requirements of aged and disable in a home. The control approach and the tone approach are used to manage the house appliances. The major organize system implementation in technology of wireless to offer distant contact from a phone Internet Protocol connectivity for access and calculating strategy and appliance remotely. The planned system no need a committed server PC with value of parallel systems and offers a new communication-protocol to observe and control a house environment with more than just the switch functionality. To express the possibility and efficiency of this system, devices like as lights switches, power plugs, and motion-sensors have been included with the planned home control system and supply more security manage on the control with low electrical energy activate method. The rank of switches is corresponding in all this control system whereby all user interfaces indicate the real time existing status. This system planned to manage electrical-appliances and devices in house with reasonably low cost of design, user friendly interface, easily install and provide high security. Research community generally specified that the network "Reconnaissance Attacks" in IPv6 are usually impossible due to they will take huge challenge to carry out address scanning of 264 hosts in an IPv6 subnet."It being deployed of IPv6 shows that it definitely enhances security and undermines the probability". This research of the IPv6 addressing-strategies at present utilizes and planned a new strategy and move toward to "mitigate reconnaissance attacks".

On-plate spot test for identification and separation of benzalkonium chloride and cetrimide in drug samples: A mechanistic view

Ali Mohammad,Asma Siddiq,Rizwana Mobin,Gaber E.- El-Desoky 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

A mechanism showing different modes of interaction of benzalkonium chloride and cetrimide with the stationary and mobile phase has been proposed which leads to the separation of this surfactant mixture. Other combination of cationic surfactants was also separated from their binary mixture by the chromatographic system comprising of silica gel and combination of green solvents as mobile phase. The effect of presence of impurities on separation process was also examined and the limits of detection of the separated surfactants were calculated. The developed method was also successfully applied for the identification of cetrimide and benzalkonium chloride in pharmaceutical formulations.

Aminopropyl-Terminated Polydimethylsiloxane과 Trichlorogermyl 곁가지 그룹을 갖는 Polyamide 블록공중합체의 합성, 구조분석 및 열적거동

Rohama Gill,Muhammad Mazhar,Sumera Mahboob,Mogammad Siddiq 한국고분자학회 2008 폴리머 Vol.32 No.3