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RISS 인기검색어
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- 저자 : Shiqing Sun (검색결과 3 건)
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Shiqing Sun,Yongkun Liu,Guohua Jiang,Bo Yu,Uwamahoro Evariste,Pianpian Ma 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.3
The fl exible electrodes are the essential components for fabricating modern fl exible supercapacitors. In this study, a compositehybrid fi lm integrated with silver nanoparticles (Ag NPs), reduced graphene oxide (rGO) and γ-MnO 2 nanorods asa fl exible electrode has been developed by the electrochemical deposition method. The substrate (rGO) of the electrode notonly provides mechanical stability but also ensures fast electron transfer during charge–discharge. The Ag NPs distributedin electrode provide the electronic channel to enhance the electric conductivity. The γ-MnO 2 electroplated on the surface ofhybrid fi lms further improved the electrochemical performance of them. The resultant γ-MnO 2 /Ag/rGO hybrid fi lms exhibita high specifi c capacitance of 1090.3 F g −1 at current density of 0.3 A g −1 . The asymmetric supercapacitor (ASC) deviceswere further fabricated by γ-MnO 2 /Ag/rGO fi lms as anode and AC/rGO fi lms as cathode electrodes within a wide operatingvoltage of 0–1.7 V. The energy density of obtained ASC devices was 71.8 Wh kg −1 at a power density of 279.4 W kg −1 .
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Zhang, Shiqing,Sun, Peng,Xiao, Xinru,Hu, Yujie,Qian, Yan,Zhang, Qian The Korean Society of Pharmacology 2022 The Korean Journal of Physiology & Pharmacology Vol.26 No.4
Epithelial-mesenchymal transition (EMT) is known to be involved in airway remodeling and fibrosis of bronchial asthma. However, the molecular mechanisms leading to EMT have yet to be fully clarified. The current study was designed to reveal the potential mechanism of microRNA-21 (miR-21) and poly (ADP-ribose) polymerase-1 (PARP-1) affecting EMT through the PI3K/AKT signaling pathway. Human bronchial epithelial cells (16HBE cells) were transfected with miR-21 mimics/inhibitors and PARP-1 plasmid/small interfering RNA (siRNA). A dual luciferase reporter assay and biotin-labeled RNA pull-down experiments were conducted to verify the targeting relationship between miR-21 mimics and PARP-1. The migration ability of 16HBE cells was evaluated by Transwell assay. Quantitative real-time polymerase chain reaction and Western blotting experiments were applied to determine the expression of Snail, ZEB1, E-cadherin, N-cadherin, Vimentin, and PARP-1. The effects of the PI3K inhibitor LY294002 on the migration of 16HBE cells and EMT were investigated. Overexpression of miR-21 mimics induced migration and EMT of 16HBE cells, which was significantly inhibited by overexpression of PARP-1. Our findings showed that PARP-1 was a direct target of miR-21, and that miR-21 targeted PARP-1 to promote migration and EMT of 16HBE cells through the PI3K/AKT signaling pathway. Using LY294002 to block PI3K/AKT signaling pathway resulted in a significant reduction in the migration and EMT of 16HBE cells. These results suggest that miR-21 promotes EMT and migration of HBE cells by targeting PARP-1. Additionally, the PI3K/AKT signaling pathway might be involved in this mechanism, which could indicate its usefulness as a therapeutic target for asthma.
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Effect of Low-Temperature Heat Treatment on PM2.5 Adsorption Properties of GO Films
Weiwu Zou,Baoshan Gu,Shiqing Sun,Shidong Wang,Xin Li,Haoqi Zhao,Peiyan Yang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.15 No.01
To explore the mechanism of GO acting on PM 2.5, a graphene oxide (GO) film was prepared via a spraying method for air purification. The effects of different media, temperature and heat treatment times on the adsorption of PM 2.5 on GO film were investigated. The morphology, composition and structure of GO materials were characterized by scanning electron microscopy (SEM), electron spectroscopy (EDS), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), infrared spectroscopy (FT-IR) and Raman spectroscopy. When the vacuum heat-treatment temperature is below 80 ℃ and the atmospheric heat-treatment temperature is below 100 ℃, the air purification performance of the film does not change significantly. With the increase in the vacuum heat-treatment temperature, the removal efficiency of PM 2.5 by GO film decreases gradually from 95% to 83%. At different times, the vacuum heat treatment increases with time, and the film removal rate shows a downward trend. As the heat-treatment temperature and time increase, a certain redox reaction occurs in the GO, and the air purification performance decreases. At a temperature of 120 ℃ and a time of 8 h, the removal rate drops to 81.68%. The adsorption of PM 2.5 by GO film mainly relies on the action of oxygen-containing functional groups.
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