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Bai, Shi-Zhong Korean Mathematical Society 2007 대한수학회지 Vol.44 No.1
It is known that connectedness is one of the important notions in topology. In this paper, a new notion of connectedness is introduced in L-topological spaces, which is called PS-connectedness. It contains some nice properties. Especially, the famous K. Fan's Theorem holds for PS-connectedness in L-topological spaces.
PS-connectedness of $L$-subsets
Shi-Zhong Bai 대한수학회 2007 대한수학회지 Vol.44 No.1
It is known that conectednes is one of the important no-tions in topology. In this paper, a new notion of conectedne s is in-troduced in L-topological spaces, which is caled PS-conectednes. Itcontains ome nice properties. Especialy, the famous K. Fa n’s Theoremholds for PS-conectednes in L-topological spaces.
Chen, Shu-Dong,Song, Mao-Min,Zhong, Zhi-Qiang,Li, Na,Wang, Pi-Lin,Cheng, Shi,Bai, Ri-Xing,Yuan, Hui-Sheng Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.3
Radixin, encoded by a gene on chromosome 11, plays important roles in cell motility, invasion and tumor progression. However, its function in pancreatic cancer remains elusive. In this study, radixin gene expression was suppressed with a lentivirus-mediated short-hairpin RNA (shRNA) method. We found that radixin shRNA caused down-regulation of radixin in PANC-1 cells, associated with inhibition of pancreatic cancer cell proliferation, survival, adhesion and invasive potential in vitro. When radixin-silenced cells were implanted in nude mice, tumor growth and microvessel density were significantly inhibited as compared to blank control cells or nonsense shRNA control cells. Thrombospondin-1 (TSP-1) and E-cadherin were up-regulated in radixin-silenced PANC-1 cells. Our results suggest that radixin might play a critical role in pancreatic cancer progression, possibly through invvolvement of down-regulation of TSP-1 and E-cadherin expression.