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      • Asian Consensus Workshop Report: Expert Consensus Guideline for the Management of Intermediate and Advanced Hepatocellular Carcinoma in Asia

        Han, Kwang-Hyub,Kudo, Masatochi,Ye, Sheng-Long,Choi, Jong Young,Poon, Roonni Tung-Ping,Seong, Jinsil,Park, Joong-Won,Ichida, Takafumi,Chung, Jin Wook,Chow, Pierce,Cheng, Ann-Lii S. Karger AG 2011 Oncology Vol.81 No.suppl1

        <P>Abstract</P><P>Hepatocellular carcinoma (HCC) is a highly prevalent disease in many Asian countries, accounting for 80% of victims worldwide. Screening programs improve the detection of early HCC and have a positive impact on survival, but the majority of HCC patients in Asia still present with advanced stage disease. The treatment outcomes of HCC are affected by multiple variables, including liver function, performance status of the patient, and tumor stage. Therefore, it is not easy to apply a multidisciplinary therapeutic approach for optimal management. At present, limited numbers of HCC patients are eligible for curative therapies such as surgery or ablation in Asia. Therefore, most patients are eligible for only palliative treatments. For optimal management, the treatment choice is guided by staging systems and treatment guidelines. Numerous staging systems have been proposed and treatment guidelines vary by region. According to the Barcelona Clinic Liver Cancer (BCLC) guideline based on evidence from randomized clinical trials, only transarterial chemoembolization (TACE) is recommended for intermediate stage HCC and sorafenib for advanced stage HCC. However, treatment guidelines from Asian countries have adopted several other therapeutic modalities such as a surgical approach, hepatic arterial infusion chemotherapy, external radiation, and their combinations based on clinical experiences for intermediate and advanced stage HCC. Although TACE is the main therapeutic modality in the intermediate stage, overall therapeutic outcomes depend on the tumor size. In the advanced stage, the prognosis depends on the tumor status, e.g. major vessel invasion or extrahepatic spread. Thus, a new staging system representing prognoses suitable for Asian HCC patients and a corresponding optimal treatment algorithm should be further investigated using evidence-based data, which will finally bring about an Asian consensus for the management of intermediate and advanced stage HCC.</P><P>Copyright © 2011 S. Karger AG, Basel</P>

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        Cost Estimation Model Based on Building Information Modeling and Virtual Reality for Customizing Presold Homes

        Kun-Chi Wang,Sheng-Han Tung 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.4

        Presold homes refer to houses that are sold before construction has begun or while the construction is still underway. To facilitate the selection and purchase of houses by clients, construction companies usually use sample houses, models, or videos to show the appearance of new houses being constructed. Clients have numerous opportunities to participate in the spatial planning and spatial allocation of the houses because these houses have not yet been constructed, and clients can direct the style and materials used for interior partition walls and furnishings. However, when discussing housing styles with their clients, construction companiesoften depend on their imagination to create three-dimensional images depicting the interior layout of houses. Construction companies can neither immediately present new styles when clients request changes to partition walls or styles nor estimate the costs of the changes. Consequently, clients cannot immediately decide on such changes, which then leads to poor communication between the two parties. Accordingly, this study designed a system that integrates building information modeling (BIM) and virtual reality (VR). Through this system, clients can change and immediately view house styles in immersive VR and decide on whether the changes meet their demands. Furthermore, the designed system is linked to a unit price database for materials. When clients make alterations in the system, it automatically calculates the costs of the changes and then helps the client determine whether the changes are within their budgets. The results of this study indicate that the designed system can accurately and rapidly achieve cost estimation. Furthermore, the proposed system ensures consistency between BIM and virtual environment information, thereby promoting the application of BIM in the stages of a building life cycle subsequent to building design.

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