http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Sharida Fakurazi (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
SAMER HASAN HUSSEIN-AL-ALI,Palanisamy Arulselvan,Sharida Fakurazi,Maznah Ismail,DENA DORNIANI,MOHD ZOBIR HUSSEIN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.2
Magnetic nanoparticles (MNPs) were prepared by the coprecipitation method using a molar ratioof Fe 3 þ:Fe 2 þof 2:1. The surface of MNP was coated with chitosan (CS) and polyethylene glycol(PEG) to form CS – MNP and PEG – MNP nanoparticles, respectively. Anthranilic acid (AA) wasloaded on the surface of the resulting nanoparticles to form AA – CS – MNP and AA – PEG – MNPnanocomposites, respectively. The nanocomposites obtained were characterized using powderX-ray di®raction (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetryanalysis (TGA), vibrating sample magnetometer (VSM) and scanning electron microscopy (SEM). XRD results showed that the as-synthesized nanocomposites are pure magnetite. FTIRresults analysis indicated the existence of two polymers on the particle surface of the MNP andthe presence of loaded AA on the surface of CS – MNP and PEG – MNP nanoparticles. Anthranilicacid loading and the release pro¯les of AA – CS – MNP and AA – PEG – MNP nanocompositesshowed that up to 8.8% and 5.5% of the adsorbed drug were released in 670 min and 771 min,respectively. Anthranilic acid release pro¯les followed a pseudo-second-order kinetic controlledprocess. The cytotoxicity of the as-synthesized anthranilic acid nanocomposities were determinedusing MTT assay using murine macrophage RAW 264.7 cells. MTT results showed that thecytotoxic e®ects of AA – CS – MNP were higher than AA – PEG – MNP against the tested cells ascompared to free anthranilic acid. In this manner, this study introduces novel anthranilic acidnanocomposites that can be used on-demand for biomedical applications.
-
Periyar Selvam Sellamuthu,,Palanisamy Arulselvan,Balu Periamallipatti Muniappan,Sharida Fakurazi,Murugesan Kandasamy 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.8
Oxidative stress in diabetic tissues is a consequence of free radical accumulation with concurrently impaired natural antioxidants status and results in oxidative tissue damage. The present study investigated the protective effects of mangiferin against pancreatic β-cell damage and on the antioxidant defense systems in streptozotocin (STZ)-induced diabetic rats. Diabetes was experimentally induced by a single intraperitoneal injection of STZ. Oxidative stress biomarkers such as tissue malondialdehyde, hydroperoxides, reduced glutathione (GSH) content, and nonenzymatic antioxidants were measured. Biochemical observations were further substantiated with histological examination and ultrastructural studies in the pancreas of diabetic, glibenclamide and mangiferin-treated diabetic rats (dosage of 40 mg/kg body weight daily for 30 days). Oral administration of mangiferin and glibenclamide to diabetic rats significantly decreased the level of blood glucose and increased levels of insulin. Additionally, mangiferin treatment significantly modulated the pancreatic nonenzymatic antioxidants status (vitamin C, vitamin E, ceruloplasmin, and reduced GSH content) and other oxidative stress biomarkers. The histoarchitecture of diabetic rats showed degenerated pancreas with lower β-cell counts, but mangiferin treatment effectively regenerated insulin secreting islet cells. The electron microscopic study revealed damaged nuclear envelope and mitochondria and fewer secretory granules in pancreas of diabetic rats; however, mangiferin treatment nearly normalized pancreatic architecture. The present findings suggest that mangiferin treatment exerts a therapeutic protective nature in diabetes by decreasing oxidative stress and protecting against pancreatic β-cell damage, which may be attributable to its antioxidative properties.
-
Isshadiba Faikah Mustafa,Mohd Zobir Hussein,Abu Seman Idris,Nur Rashyeda Ramli,Muskhazli Mustafa,Sharida Fakurazi 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.4
The endophytic bacterium, Pseudomonas aeruginosa, was successfully encapsulated into calcium carbonate microshells and coated with sodium alginate in combination with two other materials: skim milk and empty fruit bunch (EFB). The presence of bacteria cells was confirmed by a strand-like structure, a biofilm through morphology and elemental analysis. The survivability of microencapsulated bacteria was found to last for 17 months when they were maintained in a storage condition of 4 °C. Different coating materials used exhibited significant differences in the P. aeruginosa survival during the storage time. Their bioactivity against Ganoderma boninense resulted in a percentage inhibition radial growth (PIRG) value of more than 70%, which is better than its counterparts, the free Pseudomonas cells. With promising viability results of × 106 CFU/mL after three-month storage, the results demonstrate that skim milk-coated alginate might be good protection for P. aeruginosa that could sustain the viable bacteria at the target site. This is toward a greener, biological control-based plant protection for Ganoderma diseases in the oil palm planting industry.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
