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Antifungal Activity of (-)-ent-Costunolide on the Dermatophytic Fungus Trichophyton mentagrophytes
김명주,Seung Hwa Baek1 한의병리학회 2006 동의생리병리학회지 Vol.20 No.2
Bioactivity directed isolation has led to the isolation of (-)-ent-costunolide (1) as the major active compound. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (4 mm inhibition zone at 15 μg/disc).