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      • SCOPUSKCI등재SCIE

        Pre-coagulated landfill leachate treatment by Electro-oxidation using MMO/Ti, Pt/Ti, and graphite anodes

        Senem Yazici Guvenc,Yesim Daniser,Emine Can-Guven,Gamze Varank,Ahmet Demir 대한환경공학회 2023 Environmental Engineering Research Vol.28 No.1

        In this study, sequential coagulation and electro-oxidation (EO) processes were applied to landfill leachate, which is highly contaminated and complex wastewater. Since the pollutant content of the leachate was too high, the coagulation process (poly aluminum chloride (PAC) as a coagulant) was applied as a pre-treatment to reduce the cost of the EO process. The Box-Behnken design of response surface methodology was used. The color number (CN) removal efficiency estimated by the model under optimum operating conditions was 80.1%, while it was 77.6% in the experimental studies performed under optimum conditions to verify the model conformity. Multi-metal oxide doped Ti (MMO/Ti), Pt doped Ti (Pt/Ti), and graphite were used as anode and stainless steel was used as cathode in the EO process. In the EO process in which Pt/Ti anode was used, chemical oxygen demand (COD), UV<SUB>254</SUB>, and CN removal efficiencies were 52.8, 68.1, and 85.6%, respectively under the conditions of applied current 1.25 A and the pH 5. The CN value decreased to 4.2 after the coagulation process and it was 0.6 at the effluent of the EO process.

      • KCI등재

        The effect of central sensitization on disease activity measures, quality of life and clinical parameters in axial spondyloarthritis: a cross-sectional study

        Senem Şaş,Gizem Cengiz,Hüseyin Kaplan 대한류마티스학회 2023 대한류마티스학회지 Vol.30 No.3

        Objective: Despite biological drug therapy, pain remains a persistent complaint in patients with axial spondyloarthritis (axSpA). We aimed to investigate the effect of central sensitization (CS) on disease activity measures, quality of life, and clinical parameters in axSpA patients. Methods: We consecutively recruited axSpA patients who were followed up at our rheumatology outpatient clinic, and age- and sex-matched controls in this cross-sectional study. The central sensitization inventory, douleur neuropathique 4 (DN4) questions, and 2010 American College of Rheumatology fibromyalgia (FM) diagnostic criteria were applied to all individuals. The patients’ clinical parameters were recorded. The data of the patient and control groups were compared. Results: Of the 116 axSpA patients (57 female) and 95 controls (46 female) who participated in this study, CS was determined in 46.6% of axSpA patients and 13.7% of controls (p<0.001). Patients with CS exhibited high disease activity, and poor quality of life and functionality than without it (all p<0.001). The median CS, frequency of FM and frequency of neuropathic pain were higher in patients than in the controls (all p<0.001). CS-related conditions, including anxiety and depression, were higher in axSpA patients than in controls (both p<0.05). Conclusion: The results showed that CS was common in axSpA patients, and patients with CS had higher disease activity, worse quality of life, and worse functional status than those without CS.

      • KCI등재

        Radiology Residents' Awareness about Ionizing Radiation Doses in Imaging Studies Their Cancer Risk during Radiological Examinations

        Senem Divrik Gökçe,Erkan Gökçe,Melek Coşkun 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.2

        Objective: Imaging methods that use ionizing radiation have been more frequent in various medical fields with advances in imaging technology. The aim of our study was to make residents be aware of the radiation dose they are subjected to when they conduct radiological imaging methods, and of cancer risk. Materials and Methods: A total of 364 residents participated in this descriptive study which was conducted during the period between October, 2008 and January, 2009. The questionnaires were completed under strict control on a one-to-one basis from each department. A X2-test was used for the evaluation of data obtained. Results: Only 7% of residents correctly answered to the question about the ionizing radiation dose of a posteroanterior (PA) chest X-ray. The question asking about the equivalent number of PA chest X-rays to the ionizing dose of a brain CT was answered correctly by 24% of residents; the same question regarding abdominal CT was answered correctly by 16% of residents, thorax CT by 16%, thyroid scintigraphy by 15%, intravenous pyelography by 9%, and lumbar spine radiography by 2%. The risk of developing a cancer throughout lifetime by a brain and abdominal CT were 33% and 28%, respectively. Conclusion: Radiologic residents should have updated knowledge about radiation dose content and attendant cancer risks of various radiological imaging methods during both basic medical training period and following practice period. Objective: Imaging methods that use ionizing radiation have been more frequent in various medical fields with advances in imaging technology. The aim of our study was to make residents be aware of the radiation dose they are subjected to when they conduct radiological imaging methods, and of cancer risk. Materials and Methods: A total of 364 residents participated in this descriptive study which was conducted during the period between October, 2008 and January, 2009. The questionnaires were completed under strict control on a one-to-one basis from each department. A X2-test was used for the evaluation of data obtained. Results: Only 7% of residents correctly answered to the question about the ionizing radiation dose of a posteroanterior (PA) chest X-ray. The question asking about the equivalent number of PA chest X-rays to the ionizing dose of a brain CT was answered correctly by 24% of residents; the same question regarding abdominal CT was answered correctly by 16% of residents, thorax CT by 16%, thyroid scintigraphy by 15%, intravenous pyelography by 9%, and lumbar spine radiography by 2%. The risk of developing a cancer throughout lifetime by a brain and abdominal CT were 33% and 28%, respectively. Conclusion: Radiologic residents should have updated knowledge about radiation dose content and attendant cancer risks of various radiological imaging methods during both basic medical training period and following practice period.

      • KCI등재

        Effects of hot air, microwave and vacuum drying on drying characteristics and in vitro bioaccessibility of medlar fruit leather (pestil)

        Senem Suna 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.5

        The effects of microwave (90 W and 180 W), hot air (60 and 70 °C) and vacuum (60 and 70 °C with 200 and 300 mbar) drying methods on drying characteristics, total phenolic content, antioxidant capacity, color and in vitro gastrointestinal digestion of medlar pestil were investigated. Medlar showed a good potential for pestil production while being the most applicable in microwave treatments. For drying kinetics, five thin-layer drying models were applied and the Page and Modified Page were the best fitted models. L*, b*, chroma and hue angle decreased while a* generally increased in dried pestils. Dried samples showed a general decrement in phenolics and antioxidant capacity. According to in vitro gastrointestinal digestion, intestinal phase of all the samples resulted with an increment in phenolics, FRAP and DPPH compared to undigested extracts. In conclusion, different drying methods may affect the release of phenolics and antioxidant capacity, while leading to increased bioaccessibility during intestinal digestion.

      • KCI등재

        Box-Behnken design-based biodiesel wastewater treatment using sequentialacid cracking and electrochemical peroxidation process: Focus on COD, oil-greaseand volatile fatty acids removals

        Senem Yazici Guvenc,Aleyna Cebi,Emine Can-Güven,Ahmet Demir,Farshid Ghanbari,Gamze Varank 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.9

        The treatability of biodiesel wastewater by the electrochemical peroxidation process following acidificationpretreatment was investigated. Box-Behnken design, one of the experimental designs of response surface methodology,was applied to optimize the process parameters for chemical oxygen demand (COD), oil-grease, and volatile fatty acids(VFAs) removal from biodiesel wastewater. The process parameters, i.e., applied current, H2O2/COD ratio, and reactiontime, were optimized and the total cost of the process was determined. After the acidification process as a pretreatment,the COD, oil-grease, and VFAs removal efficiencies were 25.4%, 68.7%, and 50%, respectively. Optimum conditionsdetermined by the developed model for maximum oil-grease removal (98.2%) were applied: current 1.0 A, H2O2/CODratio 0.4, and reaction time 32.8 minutes. This devised Box-Behnken model predicted removal efficiencies of 45.5%,98.2%, and 49.5% for COD, oil-grease, and VFAs, respectively. The total cost of the process determined by the modeland obtained from the validation experiments was 2.03 €/m3 and 1.97 €/m3, respectively. The results of the study showedthat the applied process was efficient in pollutant removal from acidified biodiesel wastewater and the Box-Behnkendesign can be applied to explain the mechanism of the process and optimize the process parameters.

      • KCI등재

        Evaluation of Dry Eye Syndrome in Patients With Familial Mediterranean Fever: A Cross-sectional Study

        ( Senem Sas ),( Ali Kurt ),( Emine Eda Kurt ),( Fatmanur Aybala Koçak ),( Hatice Rana Erdem ) 대한류마티스학회 2020 대한류마티스학회지 Vol.27 No.4

        Objective. It has been reported that some autoimmune diseases are associated with dry eye syndrome. There are limited studies that relates dry eye syndrome in patients with Familial Mediterranean fever (FMF). The aim of this study is to evaluate the relationship between dry eye syndrome in patients with FMF comparing with healthy controls. Methods. Prospective cross-sectional study was carried out in departments of physical medicine and rehabilitation and ophthalmology clinics in a tertiary public institution with a sample of 46 participants including 23 FMF patients and 23 healthy controls. Detailed eye examination was performed in all cases and indicators of xerophthalmia were assessed by Schirmer-I test, tear break-up time (TBUT) and ocular surface disease index (OSDI). In patient group; results of FMF gene analysis, acute phase reactants, concomitant diseases and number of FMF attacks were noted. Results. The average Schirmer-I test results for right-eye were recorded as 14.74±8.38 for the FMF group and 13.09±10.54 for the healthy group; the TBUT scores were 14.69±5.32 in FMF group and 15±6.45 in the healthy group; and OSDI scores were 9.04±2.75 and 10.86±1.77 in the FMF group and the healthy control, respectively. There were no statistically significant differences between FMF and control groups in terms of Schirmer-I, TBUT, and OSDI scores (all p>0.05). No correlation was identified between acute phase reactants and the OSDI, TBUT and Schirmer-I tests for right-eye (all p>0.05). Conclusion. This study identified no correlation between dry eye and FMF. Ocular pathology is rare and infrequently reported in FMF. (J Rheum Dis 2020;27:270-276)

      • KCI등재

        Efficiency calibration of a coaxial HPGe detector-Marinelli beaker geometry using an 152Eu source prepared in epoxy matrix and its validation by efficiency transfer method

        Haluk Yücel,Senem Zümrüt,Recep Bora Narttürk,Gizem Gedik 한국원자력학회 2019 Nuclear Engineering and Technology Vol.51 No.2

        In this study, an in-house 152Eu calibration source was produced from a custom epoxy matrix with adensity of r ¼ 1.14 g cm 3, which is chemically stable and durable form after its solidification. The homogeneityof 152Eu in matrix was obtained better than 98%. For a Marinelli beaker geometry, an efficiencycalibration procedure was applied to a n-type, coaxial, 78.5% relative efficient HPGe detector in theenergy range of 121.7e1408.0 keV by using in-house 152Eu calibration source. Then the measured efficienciesfor Marinelli geometry were compared with the results calculated by MEFFTRAN and ANGLEsoftwares for the validation. Although MEFFTRAN and ANGLE have two different efficiency transfer algorithmsto calculate the efficiencies, they usually need to use a reliable and accurate reference efficiencyvalues as input data. Hence, reference efficiency values were obtained experimentally from a multinuclide standard sourcefor the same detector- Marinelli geometry. In the present source characterization, the correctionsrequired for self-absorption and true coincidence summing effects for 152Eu gamma-rays were alsoobtained for a such close counting geometry condition. The experimental results confirmed the validityof efficiency calculations obtained by MEFFTRAN and ANGLE softwares that are calculation tools.

      • SCIESCOPUSKCI등재
      • KCI등재

        Assessment of Placental Stiffness Using Acoustic Radiation Force Impulse Elastography in Pregnant Women with Fetal Anomalies

        Bircan Alan,Cemil Göya,Senem Tunç,Memik Teke,Salih Hattapog˘lu 대한영상의학회 2016 Korean Journal of Radiology Vol.17 No.2

        Objective: We aimed to evaluate placental stiffness measured by acoustic radiation force impulse (ARFI) elastography in pregnant women in the second trimester with a normal fetus versus those with structural anomalies and non-structural findings. Materials and Methods: Forty pregnant women carrying a fetus with structural anomalies diagnosed sonographically at 18–28 weeks of gestation comprised the study group. The control group consisted of 34 healthy pregnant women with a sonographically normal fetus at a similar gestational age. Placental shear wave velocity (SWV) was measured by ARFI elastography and compared between the two groups. Structural anomalies and non-structural findings were scored based on sonographic markers. Placental stiffness measurements were compared among fetus anomaly categories. Doppler parameters of umbilical and uterine arteries were compared with placental SWV measurements. Results: All placental SWV measurements, including minimum SWV, maximum SWV, and mean SWV were significantly higher in the study group than the control group ([0.86 ± 0.2, 0.74 ± 0.1; p < 0.001], [1.89 ± 0.7, 1.59 ± 0.5; p = 0.04], and [1.26 ± 0.4, 1.09 ± 0.2; p = 0.01]), respectively. Conclusion: Placental stiffness evaluated by ARFI elastography during the second trimester in pregnant women with fetuses with congenital structural anomalies is higher than that of pregnant women with normal fetuses.

      • KCI등재

        Quality of Life Assessment in Women with Breast Cancer: A Prospective Study Including Hormonal Therapy

        Fatma Sert,Zeynep Ozsaran,Erhan Eser,Senem Demirci Alanyalı,Ayfer Haydaroglu,Arif Aras 한국유방암학회 2013 Journal of breast cancer Vol.16 No.2

        Purpose: Evaluating the effect of hormonal treatment on quality of life (QoL) in breast cancer patients by using the Functional Assessment of Cancer Treatment (FACT) questionnaire is the main purpose of this trial. Methods: Breast cancer patients treated with adjuvant between January 2007 and December 2009 were evaluated. The first survey was done after patients completed their whole adjuvant treatment except for the hormonal therapy and this was as ‘basal assessment.’ The second survey was done 6 to 12 months after the basal surveys during their routine policlinic controls. The last survey was done within the last 18 to 24 months of the follow-up period. Results: The effect of marital status, number of pregnancies, residence in the village or city, hemoglobin levels, chemotherapy and hormonal therapy for any other reason except for breast cancer on the QoL could not be seen. Endocrine subscale scores were detected to be higher in patients aged >60 years than in younger ones. The other dimension scores were low in the elderly patient group. There was a statistically significant relationship between being >30 years old and improvement in the social well-being score (p=0.028). The functional well-being scores were found to be significantly higher in the patient group that had no comorbid disease (p=0.018). Endocrine subscale scores were statistically worse in patients who had psychiatric disease (p=0.057) but the general QoL data were similar with others. It was shown that all QoL scores for all dimensions had statistically significant changes (p<0.001) in terms of hormonal regimes. Conclusion: The diagnosis of breast cancer was found to be an independent factor that affects social well-being and social life in a negative way. We must give attention to complaints including complaints about sexual life and hormonal status in order to ensure compliance of patients with the required hormonal regimens. By the help of future research, we can improve the prognosis of this disease through increased treatment adherence and belief of patients.

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