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RISS 인기검색어
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- 저자 : Sedighe Hosseini (검색결과 1 건)
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Leila Nazari,Saghar Salehpour,Sedighe Hosseini,Teibeh Hashemi,Nasrin Borumandnia,Elham Azizi 대한산부인과학회 2022 Obstetrics & Gynecology Science Vol.65 No.3
ObjectiveRecurrent pregnancy loss (RPL) is a fertility problem for which no exact mechanism of abortion or efficient treatmenthas been described. This study was conducted between 2018 and 2019 to investigate the effectiveness of autologousplatelet-rich plasma (PRP) in improving the live birth rate of women with RPL who required in vitro fertilization (IVF). MethodsA total of 63 patients with at least two previous pregnancy losses and no specific cause detected for the RPL wereincluded and randomly assigned into two groups (PRP and control). Intrauterine infusion of 0.5 mL of autologous PRPwas performed 48 hours before embryo transfer in the PRP group. Women in the control group received standardtreatment. ResultsForty patients completed the study. The baseline and cycle characteristics of the participants did not differ significantlybetween the PRP and control groups. The clinical pregnancy rate was higher in the PRP group (35% vs. 20%, P=0.288). The live birth rate was 15% in the PRP group, but no live births were recorded in the control group (P=0.231). ConclusionThis is the first study to show that intrauterine infusion of PRP in patients with RPL who undergo IVF may increase thechance of live birth. 영어
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