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Fumiya Tsutsui,Keiichi Kitamura,Satoshi Nonaka 한국항공우주학회 2022 International Journal of Aeronautical and Space Sc Vol.23 No.4
A slender-bodied vehicle with asymmetrically arranged protuberance generates strong side force due to asymmetric vortices, even at a low angle-of-attack. We investigated effects of the well-known RANS turbulence models [SA-R (Crot = 0.0, 1.0, and 2.0), SST, and SST-2003] by comparing the numerically obtained side force values on supersonic slender-body, along with the flow structure. As a result, all the SA-R models showed good agreement with the experiment regardless of the Crot (which controls the degree of modification from the original SA model), although a separation point on the protuberance side slightly changed depending on the Crot value. On the other hand, as for the SST models, when the vorticity was used to evaluate eddy viscosity (original SST) the side force exhibit 44% deviation from the experiment, whereas SST-2003, in which the strain rate was employed instead, significantly reduced the discrepancy to 0.7%.
Immunocytochemistry of serotonin and galanin in the hypothalamus of the Japanese quail
Haida, Yuka,Oishi, Tadashi,Tsutsui, Kazuyoshi,Tamotsu, Satoshi Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
We investigated the interaction of serotonin and galanin (GA) by a double immunostaining method in the Japanese quail. Serotonin-immunoreactive (IR) cells were located in the paraventricular organ (PVO) and infundibular nucleus (IF). The number of the cells under short-day photoperiod (SD) was less in the dark phase than in the light phase. GA-IR cells were found in the PVO, IF and median eminence. The number of GA-IR cells in SD was significantly greater than that in long-day photoperiod (LD). Numerous GA- IR varicose fibers ran along serotonin- IR cell bodies and nerve fibers in the PVO and IF of the same sections. Very few serotonin-IR fibers ran along GA-IR cell bodies and GA-IR nerve fibers in the ventral part of the IF. The present results suggest that the possibility of functional interaction takes place between serotonin- and GA- IR neurons in the PVO and IF.
Kenji Ohwada,Tatsuo Fukuda,Jun’ichiro Mizuki,Kazuma Hirota,Hikaru Terauchi,Satoshi Tsutsui,Alfred Q. R. Baron,Hidehiro Ohwa,Naohiko Yasuda 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.31
Pb(In_(1/2)Nb_(1/2))O_3 (PIN) can be antiferroelectric (AFE), ferroelectric (FE) or a relaxor depending upon the perovskite B-site randomness. In order to clarify the effect of B-site randomness, we studied the dynamics of ordered PIN without B-site randomness (O-PIN, AFE), which will give us a clear picture of the AFE/relaxor nature of the ground state due to B-site randomness. The quasielastic (QE) scattering shows a critical slowing down near the Γ-point and the transverse acoustic (TA) mode shows a softening trend at a finite wavenumber position (not at the Γ-point) towards the AFE phase transition temperature (T_N ∼ 450 K). On the other hand, the transverse optic (TO) mode shows a softening near the Γ-point toward low temperature with no clear anomaly at T_N. These results indicate that the AFE phase transition is associated with the TA mode and the origin of the QE scattering while a ferroelectric correlation exists behind the AFE ordering. The effect of B-site randomness is finally discussed on the basis of the results.
Deep Brain Photoreceptors and Photoperiodism in Vertebrates
Oishi, Tadashi,Haida, Yuka,Okano, Keiko,Yoshikawa, Tomoko,Kawano, Emi,Nagai, Kiyoko,Fukada, Yoshitaka,Tsutsui, Kazuyoshi,Tamotsu, Satoshi Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Photoperiodism is an important adaptive phenomenon in various physiological parameters including reproduction to cope with seasonal changes. Involvement of extraretinal photoreceptors in the photoperiodism in non-mammalian vertebrates has been well established. In addition, circadian clock system is known to be involved in the photoperiodic time measurement. The pathway consists of light-input system, time measurement system (circadian clock), gonadotropin releasing hormone (GnRH) production in the hypothalamus, luteinizing hormone (LH) and follicle stimulating hormone (FSH) production in the pituitary, and final gonadal development. Recently, several laboratories reported photopigments newly cloned in the pineal, eyes and deep brain in addition to already known visual pigments in the retina. These are pinopsin, parapinopsin, VA-opsin, melanopsin, etc. All these photopigments belong to the opsin family having retinal as the chromophore. However, the function of these photopigments remains unknown. I reviewed the studies on the location of the photopigments by immunocytochemistry. I also discussed the results on the action spectra for induction of gonadal development in relation with the location of the photoreceptors. Various physiologically active substances distribute in the vertebrate brain. Such substances are GnRH, GnIH, neuropeptide Y, vasoactive intestinal peptide, c-Fos, galanin, neurosteroids, etc. I summarized the immunhistochemical studies on the distribution and the photoperiodic changes of these substances and discussed the route from the deep brain photoreceptor to GnRH cells.
Kazuya Kariyama,Kazuhiro Nouso,Atsushi Hiraoka,Hidenori Toyoda,Toshifumi Tada,Kunihiko Tsuji,Toru Ishikawa,Takeshi Hatanaka,Ei Itobayashi,Koichi Takaguchi,Akemi Tsutsui,Atsushi Naganuma,Satoshi Yasuda 대한간암학회 2024 대한간암학회지 Vol.24 No.1
Background/Aim: The aim of this study was to compare the therapeutic efficacy of ablation and surgery in solitary hepatocellular carcinoma (HCC) measuring ≤5 cm with a large HCC cohort database. Methods: The study included consecutive 2,067 patients with solitary HCC who were treated with either ablation (n=1,248) or surgery (n=819). Th e patients were divided into three groups based on the tumor size and compared the outcomes of the two therapies using propensity score matching. Results: No significant difference in recurrence-free survival (RFS) or overall survival (OS) was found between surgery and ablation groups for tumors measuring ≤2 cm or >2 cm but ≤3 cm. For tumors measuring >3 cm but ≤5 cm, RFS was significantly better with surgery than with ablation (3.6 and 2.0 years, respectively, P=0.0297). However, no significant difference in OS was found between surgery and ablation in this group (6.7 and 6.0 years, respectively, P=0.668). Conclusion: The study suggests that surgery and ablation can be equally used as a treatment for solitary HCC no more than 3 cm in diameter. For HCCs measuring 3-5 cm, the OS was not different between therapies; thus, ablation and less invasive therapy can be considered a treatment option; however, special caution should be taken to prevent recurrence.