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Ponmana Selvan Arumugam,Ganapathy Gandhi,Saravanan Murugesan,Veerasivaji Ramachandran 대한수학회 2023 대한수학회논문집 Vol.38 No.4
In this paper, we prove the Hyers-Ulam stability and Mittag-Leffler-Hyers-Ulam stability of a differential equation of Logistic growth in a population by applying Laplace transforms method.
Balakrishnan Santhanaraj,Ponnusamy Ponmurugan,Sathibabu Uddandrao V. V.,Saravanan Ganapathy 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.3
We evaluated the beneficial effects of some varieties of Saudi Arabian date fruits against Freund’s complete adjuvant (FCA)- induced rheumatoid arthritis in rats. Arthritic rats were treated orally for 30 days with methanolic extracts of Sukkari, Ekhlass Almajmaah, Abu Minifee and Dawee verities [500 mg/kg body weight (BW)] and Indomethacin (10 mg/kg BW) administered as standard for comparison. We evaluated the effects of the extracts on arthritis (paw volume and arthritis score), body weight, renal marker levels, and bone metabolic enzymes as well as the antioxidant activities in the experimental and control rats. All verities of date fruit extracts were significantly decreased the arthritis which was evident with arthritis score, paw volume as well as the maintenance of biochemical parameters and antioxidant activities. The present study was suggested that date fruit extracts has prominent anti-arthritic activity which may be attributed to its anti-inflammatory and antioxidant activities.
V. V. Sathibabu Uddandrao,Brahmanaidu Parim,P. R. Nivedha,K. Swapna,P. Rameshreddy,S. Vadivukkarasi,Mustapha Shabana Begum,Saravanan Ganapathy 경희대학교 융합한의과학연구소 2019 Oriental Pharmacy and Experimental Medicine Vol.19 No.3
Pomegranate (Punica granatum Linn), has been widely used in India’s ancient Ayurveda system of traditional medicine which is commonly portrayed as a constituent in remedies. The present study was aimed to investigate the anticancer activity of the aqueous extract of P. granatum fruits (PGET) against ehrlich-ascites-carcinoma (EAC)-bearing Swiss albino mice. The PGET were administered to EAC bearing mice at the doses of 100, 200 and 400 mg/kg body weight (BW) intraperitonially for 14 successive days and 24 h of last dose and 18 h of fasting, the mice were sacrifced and the anticancer efect of PGET was appraised by evaluating tumor volume, viable, nonviable tumor cell count, tumor weight, hematological, biochemical parameters and histopathological changes of EAC mice. PGET showed momentous decrease in tumor volume, viable cell count, tumor weight and elevated the life span of EAC bearing mice. Hematological profle such as RBC, hemoglobin and lymphocyte count reverted to normal level in PGET treated mice. The extract at 400 mg/kg BW showed a noteworthy reduction in the level of lipid peroxidation and considerably increased the levels of antioxidant enzymes in the liver and observed signifcant restoration of histopathological changes in experimental animals. Hence, the current study revealed that the PGET was efcient in inhibiting the tumor growth in ascitic models and that is comparable to 5-Fluorouracil. The anticancer properties of P. granatum could be due to the presence of the various phytoconstituents in it.