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        Etiology of Bacteremia Under Haemodialysis Patients and Antibiotics Susceptibility Profile of Isolated Bacteria

        Assane Dieng,Magatte Niang,Awa Ba Diallo,Maria Faye,Gora Lo,Serigne Mbaye Lo Ndiaye,Alioune Tine,Safietou Ngom Cisse,Habsa Diagne,Moustapha Cisse,Sény Ndiaye,Djibril Boiro,Ndiaye Halimatou Diop,Camara 대한미생물학회 2023 Journal of Bacteriology and Virology Vol.53 No.2

        In nephrological pathology, incidence of bacteria is mainly correlated with theincreased use of central or peripheral venous catheters, which is unavoidable inhemodialysis. The aim of this study is to determine bacteriological etiologies ofbacteremia among hemodialysis patients between January and December 2021and to determine their antibiotics susceptibility profiles. Blood culture balloonsreceived from the Nephrology Department were immediately incubated in theBactec FX 40. With the detection of an alarm due to growing suspicion of micro-organisms, identification of the suspected germ and antimicrobial susceptibilitytesting were performed. 37 (53%) blood cultures were positive with a predomi-nance in women (54%). Gram negative bacteria was most isolated in bacteremiawith 59% rate. Among bacteria responsible of bacteremia, Staphylococcus aureus(n=13; 36%), Enterobacter cloacae (n=8; 22%), Escherichia coli (n=6; 16%) andKlebsiella pneumoniae (n=4; 11%) were most important. Regarding antibioticssusceptibility of bacteria, oxacillin (83%), tobramycin (92%), gentamycin (100%)and vancomycin (100%) were most active in S. aureus. For E. cloacae, cefepim(88%), cefixim (75%), tobramycin (88%), imipenem (100%) and tigecyclin (100%)were most active. Regarding of E. coli, imipenem (100%), ceftazidim (83%),cefoxitin (83%), amikacin (100%) and gentamicin (83%) were most active. Inconclusion, this study shows the high rate of bacteremia in nephrology depart-ment of CHNU Aristide Le Dantec with antibiotics more or less active.

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