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      • Distribution of stress state in the Nankai subduction zone, southwest Japan and a comparison with Japan Trench

        Lin, W.,Byrne, T.B.,Kinoshita, M.,McNeill, L.C.,Chang, C.,Lewis, J.C.,Yamamoto, Y.,Saffer, D.M.,Casey Moore, J.,Wu, H.Y.,Tsuji, T.,Yamada, Y.,Conin, M.,Saito, S.,Ito, T.,Tobin, H.J.,Kimura, G.,Kanagaw Elsevier Scientific Publishing Co 2016 Tectonophysics Vol.692 No.2

        <P>To better understand the distribution of three dimensional stress states in the Nankai subduction zone, southwest Japan, we review various stress-related investigations carried out in the first and second stage expeditions of the Nankai Trough Seismogenic Zone Experiment (NanTroSEIZE) by the Integrated Ocean Drilling Program (IODP) and compile the stress data. Overall, the maximum principal stress sigma(l) in the shallower levels (<similar to 1 km) is vertical from near the center of forearc basin to near the trench and; the maximum horizontal stress S-Hmax (interpreted to be the intermediate principal stress sigma(2)) is generally parallel to the plate convergence vector. The exception to this generalization occurs along the shelf edge of the Nankai margin where S-Hmax, is along strike rather than parallel to the plate convergence vector. Reorientation of the principal stresses at deeper levels (e.g., >similar to 1 km below seafloor or in underlying accretionary prism) with sigma(1) becoming horizontal is also suggested at all deeper drilling sites. We also make a comparison of the stress state in the hanging wall of the frontal plate-interface between Site C0066 in the Nankai and Site C0019 in the Japan Trench subduction zone drilled after the 2011 Mw 9.0 Tohoku-Oki earthquake. In the Japan Trench, a comparison between stress state before and after the 2011 mega-earthquake shows that the stress changed from compression before the earthquake to extension after the earthquake. As a result of the comparison between the Nankai Trough and Japan Trench, a similar current stress state with trench parallel extension was recognized at both C0006 and C0019 sites. Hypothetically, this may indicate that in Nankai Trough it is still in an early stage of the interseismic cycle of a great earthquake which occurs on the decollement and propagates to the toe (around site C0006). (C) 2015 Elsevier B.V. All rights reserved.</P>

      • SCIESCOPUSKCI등재
      • INVESTIGATING THE DECISION TO EXPORT TO MEXICO BY MEDIUM-SIZE U.S. INSTRUMENT MANUFACTURERS

        Zoher E Shipchandler,James S Moore People&Global Business Association 2000 Global Business and Finance Review Vol.5 No.2

        The instrument manufacturing industry is examined via multiple discriminant analysis (MDA) to determine the relative influence of factors impacting on the decision to export from the U.S. to Mexico. Dominant influences are found to be the perceived uniqueness of the firm's products, the degree of utilization of the firm's domestic productive capacity, the opportunity for domestic market growth, and recent trends in the firm's profitability. Interestingly, the three latter influences are linked to the decision in such a way as to suggest that the decision to export to Mexico is made more out of "need" than out of strength. The model is validated on a hold out sample that performs considerably better than chance.

      • KCI등재

        Performance Improvement in the Modern American Hospital

        Moore , Kenneth S. 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.3

        Our plan for the future of our Performance Improvement Program is to continue the team improvement process, to measure outcomes of patient care, to improve processes and systems within the hospital. We must act on data and limit politics in the decision-making process. In conclusion, it takes a commitment by everyone to improve the quality of care provided to patients throughout the hospital organization. We must all work for the best quality and the most efficient healthcare for the members of our communities.

      • KCI등재후보

        Behaviour of steel joints under fire loading

        Luís Simões da Silva,Aldina Santiago,Paulo Vila Real,David Moore 국제구조공학회 2005 Steel and Composite Structures, An International J Vol.5 No.6

        This paper presents a state-of-the-art on the behaviour of steel joints under fire loading and some recent developments in this field, currently being carried out by the authors. Firstly, a review of the experimental research work on steel joints is presented, subdivided into isolated member tests, sub-structure tests and tests on complete building structures. Special emphasis is placed on the seventh Cardington test, carried out by the authors within a collaborative research project led by the Czech Technical University in Prague. Secondly, a brief review of various temperature distributions within a joint is presented, followed by a discussion of the behaviour of isolated joints at elevated temperature, focussing on failure modes and analytical procedures for predicting the moment-rotation behaviour of joints at elevated temperature. Finally, a description of the coupled behaviour of joints as part of complete structures is presented, describing previous work and investigations on real fire (including heating and cooling phases) currently being carried out by the authors.

      • KCI등재

        Safety of Autologous Umbilical Cord Blood Therapy for Acquired Sensorineural Hearing Loss in Children

        Linda S. Baumgartner,Ernest Moore,David Shook,Steven Messina,Mary Clare Day,Jennifer Green,Rajesh Nandy,Michael Seidman,James E. Baumgartner 대한청각학회 2018 Journal of Audiology & Otology Vol.22 No.4

        Background and Objectives: Sensorineural hearing loss (SNHL) in children is associated with neurocognitive morbidity. The cause of SNHL is a loss of hair cells in the organ of Corti. There are currently no reparative treatments for SNHL. Numerous studies suggest that cord blood mononuclear cells (human umbilical cord blood, hUCB) allow at least partial restoration of SNHL by enabling repair of a damaged organ of Corti. Our objective is to determine if hUCB is a safe treatment for moderate to severe acquired SNHL in children. Subjects and Methods: Eleven children aged 6 months to 6 years with moderate to severe acquired SNHL were treated with intravenous autologous hUCB. The cell dose ranged from 8 to 30 million cells/kg body weight. Safety was assessed by measuring systemic hemodynamics during hUCB infusion. Infusion-related toxicity was evaluated by measuring neurologic, hepatic, renal and pulmonary function before and after infusion. Auditory function, auditory verbal language assessments and MRI with diffusion tensor imaging (DTI) were obtained before and after treatment. Results: All patients survived, and there were no adverse events. No infusionrelated changes in hemodynamics occurred. No infusion-related toxicity was recorded. Five subjects experienced a reduction in auditory brainstem response (ABR) thresholds. Four of those 5 subjects also experienced an improvement in cochlear nerve latencies. Comparison of MRI with DTI sequences obtained before and after treatment revealed increased fractional anisotropy in the primary auditory cortex in three of five subjects with reduced ABR thresholds. Statistically significant (p<0.05) reductions in ABR thresholds were identified. Conclusions: TIntravenous hUCB is feasible and safe in children with SNHL.

      • KCI등재

        Quantitative trait loci analysis of morphological traits in Citrus

        Mehtap S¸ ahin-C¸ evik,Gloria A. Moore 한국식물생명공학회 2012 Plant biotechnology reports Vol.6 No.1

        The objectives of this study were to understand the genetic basis of morphological variation observed in the genus Citrus and its relatives and to identify genomic regions associated with certain morphological traits using genetic linkage mapping and quantitative trait loci (QTLs) analysis with random amplified polymorphic DNA (RAPD) markers. First, a genetic linkage map was constructed with RAPD markers obtained by screening 98 progeny plants from a {Citrus grandis 9 [C. paradisi 9 Poncirus trifoliata]} 9 {[(C. paradisi 9 P. trifoliata) 9 C. reticulata] 9 [(C. paradisi 9 Poncirus trifoliata) 9 C. sinensis]} intergeneric cross. The map contains 69 RAPD markers distributed into nine linkage groups. Then, 17 different morphological traits, including six tree and two leaf characters of 98 progeny plants and six floral and three fruit characters of about half of the same progeny plants were evaluated for 2 years and statistically analyzed for variation. Statistical analysis of individual traits indicated that trunk diameter and growth, tree height, canopy width, tree vigor and growth, leaf length and width, petal and anther numbers, petal length and width, length of pistil and style, fruit length and diameter, and fruit segment number showed normal or close to normal distribution, suggesting that these traits may be inherited quantitatively. Quantitative data from the morphological traits were analyzed to detect markers and putative QTLs associated with these traits using interval mapping method. QTL analysis revealed 18 putative QTLs of LOD[3.0 associated with 13 of the morphological traits analyzed. The putative QTLs were distributed in several different linkage groups, and QTLs associated with similar traits were mostly mapped to the same LG or similar locations in the linkage group, indicating that the same genomic region is involved in the inheritance of some of the morphological traits.

      • SCIESCOPUSKCI등재

        Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

        ( Judith S Moore ),( Peter R Gibson ),( Rebecca E Burgell ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2018 Journal of Neurogastroenterology and Motility (JNM Vol.24 No.1

        The concept of therapeutic percutaneous neuromodulation has, until recently, been limited by the ability to penetrate deeply enough to stimulate internal organs. By utilizing 2 medium frequency, slightly out of phase electrical currents passing diagonally through the abdomen, a third, low frequency current is created at the point of bisection. This interferential current appears to stimulate nerve fibers in the target organs and may have a therapeutic action. The aim of the study is to review the use of transcutaneous interferential electrical stimulation with a focus on its application in gastroenterology, particularly in motility disorders. Studies involving use of interferential current therapy were searched from Medline, PubMed, and Scopus databases, and articles pertaining to history, its application and all those treating abdominal and gastrointestinal disorders were retrieved. Seventeen studies were identified, 13 involved children only. Eleven of these were randomised controlled trials (3 in adults). Four trials were from the one center, where each paper reported on different outcomes such as soiling, defecation frequency, quality of life, and colon transit studies from the one pool of children. All studies found statistically significant improvement in symptom reduction. However, weaknesses in study design were apparent in some. In particular, finding an adequate placebo to interferential current therapy has been difficult. Interferential current therapy shows potential as a novel, non-pharmacological and economical means of treating gastrointestinal dysfunction such as constipation. More studies are needed particularly in the adult population. However, the design of a suitable placebo is challenging. (J Neurogastroenterol Motil 2018;24:19-29)

      • Component Analysis of Esophageal Cancer Incidence in Kazakhstan

        Igissinov, S.,Igissinov, N.,Moore, M.A.,Kozhakhmetov, S.,Igissinova, G.,Sarsenova, S.,Aldiyarova, G.,Bilyalova, Z.,Zhabagin, K.,Manambayeva, Z. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

        Esophageal cancer (EC) incidence rates in Kazakhstan were assessed by component analysis based on primary registered cases in 2001-2010. It was found that despite an apparent general decrease in the number of EC patients in Kazakhstan, a potential increase should be evaluated, due to changes in aging as well as the increase in population. Some problems of EC patients' registration were broached with an emphasis on the importance of the expected absolute number and reasons for undercounting in the country. Based on these, ways of improving the recording and registration of such patients in the country were suggested.

      • The safety and efficacy of laparoscopic surgical staging of apparent stage I ovarian and fallopian tube cancers

        ( Dennis S. Chi ),( Nadeem R. Abu-Rustum ),( Yukio Sonoda ),( Joseph Ivy ),( Eunice Rhee B. A. ),( Kathleen Moore ),( Douglas A. Levine ),( Richard R. Barakat ) 대한산부인과학회 2007 서울심포지움 Vol.12 No.-

        Objective: To compare the safety and efficacy of laparoscopic (LSC) staging of ovarian or fallopian tube cancers to staging via laparotomy (LAP) for epithelial ovarian carcinoma (EOC). Study Design: We performed a case-control study of all patients (pts) with apparent stage I adnexal cancers who had LSC staging from 10/00-3/03. The control group consisted of all pts with apparent stage I EOC who had staging via LAP during the same time period. Results: Staging was LSC in 20 pts and via LAP in 30.There were no differences in mean age and body mass index. There were also no differences in omental specimen size and number of lymph nodes removed. Estimated blood loss and hospital stay were lower for LSC, while operating time was longer. There were no conversions to LAP or complications in the LSC group compared with 3 minor complications in the LAP group. Conclusion: In this preliminary analysis, it appears that pts with apparent stage I ovarian or fallopian tube cancer can safely and adequately undergo LSC surgical staging.

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