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K. Vinaya, R. Kavitha,C. S. Ananda Kumar,S. B. Benaka Prasad,S. Chandrappa,S. A. Deepak,S. Nanjunda Swamy,S. Umesha,K. S. Rangappa 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.1
Several 1-benzhydryl-sulfonyl-4-(3-(piperidin-4-yl)propyl)piperidine derivatives 8(a-j) were prepared by the treatment of substituted benzhydryl chlorides with 4-(3-(piperidin-4-yl)propyl)piperidine followed by N-sulfonation with sulfonyl chlorides in the presence of dry methylene dichloride and triethyl amine. The synthesized compounds were characterized by 1H-NMR, IR, and elemental analysis. All the synthesized compounds were evaluated in vitro for their efficacy as antimicrobial agents by artificial inoculation technique against standard strains of two important bacterial viz., Xanthomonas axonopodis pv. vesicatoria and Ralstonia solanacearum as well as and two fungal pathogens namely Alternaria solani and Fusarium solani of tomato plants. We have briefly investigated the structure-activity relation studies and reveal that the nature of substitutions on benzhydryl ring and sulfonamide ring influences the antibacterial activity. Among the synthesized new compounds 8b, 8d, 8g, 8h, 8i, and 8j were showed significant potent antimicrobial activities compared to the standard drugs Chloramphenicol, Mancozeb.
권동승,박종대,Kwon, D.S.,Park, J.D. 한국전자통신연구원 2020 전자통신동향분석 Vol.35 No.2
Distributed Ledger Technology (DLT) refers to a process and related technologies that enable a person to safely suggest, verify, and record state changes (usually updates) to synchronize ledgers distributed across network nodes. DLTs are becoming increasingly important as data management requirements evolve. Therefore, they need to understand the current state of standards (such as distributed storage and access technologies) to address future requirements. This paper provides ITU-T FG-DLT standard activities, such as standardization ization trends, use cases, reference architectures, platform evaluation criteria and future prospects.