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RISS 인기검색어
- 검색키워드
- 저자 : Rose James E. (검색결과 2 건)
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Brian Kenneth E. Eduarte,Nicole Andrey Acosta,Jenela Pauline Lumanlan,Jhevia E. agnampo,Diana Rose Medrano,Kaori Ann B. Vicente,James Patrick C. Picar ASCONS 2019 IJBSA Vol.1 No.1
Background/Objectives: The fire related injuries such as burns are one of the main problems of the community. It is because of the insufficient ideas in wound healing and lack of financial capabilities resulting into self-medication. Methods/Statistical analysis: In this study, the researchers will prepare an ointment from milkfish skin and scale added to soft paraffin in 70 C until it congeals. The milkfish is known having high content of riboflavin and vitamin B complex that is a big impact to fasten the first-degree burn healing process. The milkfish skin and scales are also to be extracted using Gamma Irradiation as a manner of sterilization and for preservation of collagen and vitamin B content. The experimental rats will be induced of burn wounds by 5 seconds in the back part using cylindrical heat steel to be associated in 100C boiling water which will be treated with the prepared ointment. The epithelialization times, wound contraction and histological examination will be observed and the data recorded is to be analyzed using one-way ANOVA and repeated measures. Findings: This study deals with scientific experimentation to identify the potential of Milkfish skin and scale in wound healing. Improvements/Applications: If proven effective, it may be utilized as an alternative wound healing agent.
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Hasson Denise C.,Mohan Shruthi,Rose James E.,Merrill Kyle A.,Goldstein Stuart L.,Benoit Stefanie W.,Varnell Charles D. 대한진단검사의학회 2024 Annals of Laboratory Medicine Vol.44 No.1
Background: Abnormal serum magnesium (Mg) concentrations are common and associated with worse mortality in kidney-transplant recipients. Many kidney and transplant-related factors affect Mg homeostasis. The concentration of the active form, ionized Mg (iMg), is not measured clinically, and total Mg (tMg) and iMg correlations have conflicted. We hypothesized that iMg and tMg concentrations show poor categorical agreement (i.e., low, normal, and high) in kidney-transplant recipients but that ionized calcium (iCa) correlates with iMg. Methods: We retrospectively evaluated hypomagnesemia in kidney-transplant recipients over a 2-yr period. We prospectively collected blood at 0–28 days post-transplant to measure correlations between iMg and iCa/tMg. iMg and iCa concentrations in the reference ranges of 0.44–0.65 and 1.0–1.3 mmol/L, respectively, were considered normal. Fisher’s exact test and unweighted kappa statistics revealed category agreements. Pearson’s correlation coefficients and linear regression measured correlations. Results: Among 58 retrospective kidney-transplant recipients, 54 (93%) had tMg<0.66 mmol/L, 28/58 (48%) received Mg supplementation, and 20/28 (71%) had tacrolimus dose adjustments during supplementation. In 13 prospective transplant recipients (N=43 samples), iMg and tMg showed strong category agreement (P=0.0003) and correlation (r=0.71, P<0.001), whereas iMg and iCa did not (P=0.7; r=–0.25, P=0.103, respectively). Conclusions: tMg and iMg exhibited strong correlation following kidney transplantation. However, iCa may not be an accurate surrogate for iMg. Determining the effect of Mg supplementation and the Mg concentration where supplementation is clinically necessary are important next steps.
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