All-Optical Binary Full Adder Using Logic Operations Based on the Nonlinear Properties of a Semiconductor Optical Amplifier

Sanmukh Kaur,Rajinder Singh Kaler,Tara-Singh Kamal 한국광학회 2015 Current Optics and Photonics Vol.19 No.3

We propose a new and potentially integrable scheme for the realization of an all-optical binary fulladder employing two XOR gates, two AND gates, and one OR gate. The XOR gate is realized usinga Mach-Zehnder interferometer (MZI) based on a semiconductor optical amplifier (SOA). The AND andOR gates are based on the nonlinear properties of a semiconductor optical amplifier. The proposed schemeis driven by two input data streams and a carry bit from the previous less-significant bit order position. In our proposed design, we achieve extinction ratios for Sum and Carry output signals of 10 dB and 12dB respectively. Successful operation of the system is demonstrated at 10 Gb/s with return-to-zeromodulated signals

Ultrahigh Speed Reconfigurable Logic Operations Based on Single Semiconductor Optical Amplifier

Sanmukh Kaur,Rajinder-Singh Kaler 한국광학회 2012 Current Optics and Photonics Vol.16 No.1

We demonstrate an optical gate architecture using a single SOA to perform AND, OR and NOT logic functions. Simple reconfigurable all-optical logic operations are implemented using RZ modulated signals at 40 Gb/s. Contrast ratio and extinction ratio values have been analysed for the different types of logic gates. Maximum extinction ratio and contrast ratio achieved are 19dB and 17.2 dB respectively. Simple structure and potential for integration makes this architecture an interesting approach in photonic computing and optical signal processing.

Assessment of Genetic Diversity in Cabbage Cultivars Using RAPD and SSR Markers

Bhawna Saxena,Rajinder Kaur,Satya Vrat Bhardwaj 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.3

Genetic relationship and diversity among seven cabbage cultivars were analyzed using RAPD and SSR markers. These cultivars are of great commercial value in India and are confirmed for their reaction to black rot caused by Xanthomonas campestris pv. campestris. However, so far the extent of genetic diversity and relatedness has not been studied in these cultivars. A total of 17selected RAPD primers generated 90 bands, 76 of which were polymorphic (84.44%). In addition, 27 selected SSR primers generated 67 amplified bands with 59 of which were polymorphic (87.6%). Though both the marker techniques were able to discriminate the cultivars effectively, analysis of combined data of markers (RAPD and SSR) resulted in better distinction of cultivars. By combining both the markers, a total of 157 bands were detected of which 135 bands (85.98%) were polymorphic, i.e. an average of 5.95 bands per primer. High level of polymorphism (> 85%) recorded with two different marker systems indicated a high level of genetic variation existing among the cultivars. Genetic relationship estimated using similarity co-efficient (Jaccard’s) values between different pairs of cultivars varied from 0.21 to 0.77 in RAPD, 0.42 to 0.82 in SSR, and 0.43 to 0.89 with combined markers. A high correspondence had been recorded between the values of genetic variations generated by UPGMA, clustering, and scatter plot diagrams. The cultivars ‘January King Sel. Improved’ and ‘Golden Acre’ are highly divergent cultivars as demonstrated by both the marker systems.

Realization of High Speed All-Optical Half Adder and Half Subtractor Using SOA Based Logic Gates

Simranjit Singh,Rajinder Singh Kaler,Rupinder Kaur 한국광학회 2014 Current Optics and Photonics Vol.18 No.6

In this paper, the scheme of a single module for simultaneous operation of all-optical computing circuits, namely half adder and half subtractor, are realized using semiconductor optical amplifier (SOA) based logic gates. Optical XOR gate by employing a SOA based Mach-Zehnder interferometer (MZI) configuration is used to get the sum and difference outputs. A carry signal is generated using a SOA-four wave mixing (FWM) based AND gate, whereas, the borrow is generated by employing the SOA-cross gain modulation (XGM) effect. The obtained results confirm the feasibility of our configuration by proving the good level of quality factor i.e. ~5.5, 9.95 and 12.51 for sum/difference, carry and borrow, respectively at 0 dBm of input power.

Assessment of Genetic Diversity in Cabbage Cultivars Using RAPD and SSR Markers

Saxena, Bhawna,Kaur, Rajinder,Bhardwaj, Satya Vrat 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.3

Genetic relationship and diversity among seven cabbage cultivars were analyzed using RAPD and SSR markers. These cultivars are of great commercial value in India and are confirmed for their reaction to black rot caused by Xanthomonas campestris pv. campestris. However, so far the extent of genetic diversity and relatedness has not been studied in these cultivars. A total of 17 selected RAPD primers generated 90 bands, 76 of which were polymorphic (84.44%). In addition, 27 selected SSR primers generated 67 amplified bands with 59 of which were polymorphic (87.6%). Though both the marker techniques were able to discriminate the cultivars effectively, analysis of combined data of markers (RAPD and SSR) resulted in better distinction of cultivars. By combining both the markers, a total of 157 bands were detected of which 135 bands (85.98%) were polymorphic, i.e. an average of 5.95 bands per primer. High level of polymorphism (> 85%) recorded with two different marker systems indicated a high level of genetic variation existing among the cultivars. Genetic relationship estimated using similarity co-efficient (Jaccard's) values between different pairs of cultivars varied from 0.21 to 0.77 in RAPD, 0.42 to 0.82 in SSR, and 0.43 to 0.89 with combined markers. A high correspondence had been recorded between the values of genetic variations generated by UPGMA, clustering, and scatter plot diagrams. The cultivars 'January King Sel. Improved' and 'Golden Acre' are highly divergent cultivars as demonstrated by both the marker systems.

Recent advances in CRISPR/Cas mediated genome editing for crop improvement

Samriti Sharma,Rajinder Kaur,Anupama Singh 한국식물생명공학회 2017 Plant biotechnology reports Vol.11 No.4

Plant breeding is one of the oldest sustainable agriculture methods used to increase the yield, quality and other biomaterial for human use. Many crops like fruits, vegetables, ornamental flowers, shrubs and trees, have been long cultivated to satisfy human food and aesthetical needs. Conventional breeding technologies like selection, hybridization, mutation through physical and chemical methods, and modern transgenic approaches are often used to improve the desired traits without inducing the pleiotropic effects. But these breeding methods are highly laborious and complicated to enhance crop production. Recently, targeted genome editing through engineered nuclease including zinc finger nuclease, transcription activator like effector nuclease and clustered regularly interspaced short palindromic repeats (CRISPRs) have been used to improve various traits in plants. Genome editing has emerged as a novel alternative approach to classical breeding with higher mutagenic efficiency. Here, we briefly cover the strengths of CRISPRs in comparison with other genome editing techniques. We also discuss its potential applications in genetic improvement of various crops and future prospective.

On the Optimization of Raman Fiber Amplifier using Genetic Algorithm in the Scenario of a 64 nm 320 Channels Dense Wavelength Division Multiplexed System

Simranjit Singh,Sonak Saini,Gurpreet Kaur,Rajinder Singh Kaler 한국광학회 2014 Current Optics and Photonics Vol.18 No.2

For multi parameter optimization of Raman Fiber Amplifier (RFA), a simple genetic algorithm is presented in the scenario of a 320 channel Dense Wavelength Division Multiplexed (DWDM) system at channel spacing of 25 GHz. The large average gain (> 22 dB) is observed from optimized RFA with the optimized parameters, such as 39.6 km of Raman length with counter-propagating pumps tuned to 205.5 THz and 211.9 THz at pump powers of 234.3 mW, 677.1 mW respectively. The gain flattening filter (GFF) has also been optimized to further reduce the gain ripple across the frequency range from 190 to 197.975 THz for broadband amplification.

Polymorphic Variation in Glutathione-S-transferase Genes and Risk of Chronic Myeloid Leukaemia in the Kashmiri Population

Bhat, Gulzar,Bhat, Ashaqullah,Wani, Aadil,Sadiq, Nida,Jeelani, Samoon,Kaur, Rajinder,Masood, Akbar,Ganai, Bashir Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

Cancer is a complex disease and the genetic susceptibility to it could be an outcome of the inherited difference in the capacity of xenobiotic metabolizing enzymes. Glutathione-S-transferases (GSTs) are phase II metabolizing enzymes whose various genotypes have been associated with increased risk of different types of cancer. Null mutations caused by the deletion of the entire gene result in the absence of the enzymatic activity and increase in the risk of developing cancer including chronic myeloid leukaemia (CML). In the present case-control study we evaluated the effect of null mutations in GSTM1 and GSTT1 genes on the risk of developing CML. The study included 75 CML patients (43 males and 32 females; age (mean ${\pm}$ S.D) $42.3{\pm}13.4$ years) and unrelated non-malignant controls (76 male and 48 females; age (mean ${\pm}$ S.D) $41.5{\pm}12.9$). The distribution of GSTM1 and GSTT1 genotypes in CML patients and controls was assessed by multiplex-PCR method. Logistic regression was used to assess the relationship between GSTM1 and GSTT1 genotypes and risk of CML. Chi-square test was used to evaluate the trend in modulating the risk to CML by one or more potential high risk genotype. Although GSTM1 null genotype frequency was higher in CML patients (41%) than in the controls (35%), it did not reached a statistical significance (OD = 1.32, 95% CI: 0.73-2.40; P value = 0.4295). The frequency of GSTT1 null genotypes was higher in the CML patients (36%) than in the controls (21%) and the difference was found to be statistically significant (OD = 2.12, 95% CI: 1.12-4.02; P value = 0.0308). This suggests that the presence of GSTT1genotype may have protective role against the CML. We found a statistically significant (OD = 3.09, 95% CI: 1.122-8.528; P value = 0.0472) interaction between the GSTM1 and GSTT1 null genotypes and thus individuals carrying null genotypes of both GSTM1 and GSTT1 genes are at elevated risk of CML.