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- 저자 : Rahul Davis (검색결과 2 건)
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Rahul Davis,Abhishek Singh,Robson Bruno Dutra Pereira,Roberta Maia Sabino,Ketul Popat,Paulo Soares,Lincoln Cardoso Brandão 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.6
Shape memory alloys are mainly used in medical devices and surgical implants due to their biocompatibility. Machining these alloys into intricate patterns can be challenging due to their poor thermal conductivity which could lead to a poor surface finish. The poor surface finish causes a release of toxic elements such as Nickel, leading to contact allergies and thus deteriorating its biocompatibility. Using the right cooling technology can help improve their machinability and overcome issues related to surface integrity. The current study investigates the effect of milling parameters (cutting-speed, feed rate, and depth of cut) and different cooling strategies (flood coolant, cryogenic liquid nitrogen, and a hybrid approach) on the surface integrity of F2063 Ni55.6Ti44.4 shape memory alloy. In addition, the effect of cryogenically treating the cutting tool for further enhancement of surface finish was investigated. A considerable modification on the milled surfaces was observed when using the hybrid cooling/milling approach and cryo-treated tools in terms of morphological, chemical compositional, crystallographic, and microhardness. In addition, this modified surface had a noticeably improved bioactivity due to enhanced hydrophobicity (with contact angle 92°) and surface topography (Ra: 341.69 nm), which favoured cell adhesion and proliferation. The results indicate that the modified Ni55.6Ti44.4 alloy surface might be adequate for use in medical applications.
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( Anthony Horton ),( Brian Sullivan ),( Katie Charles ),( Thasha Mcintosh ),( Andrea Davis ),( Ziad Gellad ),( Rahul Shimpi ),( C Prakash Gyawali ),( Amit Patel ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2020 Journal of Neurogastroenterology and Motility (JNM Vol.26 No.4
Background/Aims Esophageal baseline impedance (BI) can be extracted from pH-impedance tracings as mean nocturnal baseline impedance (MNBI), and from high-resolution impedance manometry (HRIM), but it is unknown if values are similar between acquisition methods across HRIM manufacturers. We aim to assess correlations between MNBI and BI from HRIM (BI-HRIM) from 2 HRIM manufacturers in the setting of physiologic acid exposure time (AET). Methods HRIM and pH-impedance monitoring demonstrating physiologic AET (< 4%) off proton pump inhibitors were required. BI-HRIM was extracted as the average from 5 cm and 10 cm above the lower esophageal sphincter. Distal BI-HRIM (DBI-HRIM) was also extracted from the most distal channel (Medtronic studies). MNBI was extracted from 6 channels. Concordance between BI-HRIM across manufacturers with MNBI was analyzed. Results Thirty-six patients met the inclusion criteria (59.6 ± 1.7 years; 22% female; body mass index 30.5 ± 0.7; AET 1.6 ± 0.2%). Although MNBI was similar at all channels (P ≥ 0.18), Diversatek BI-HRIM was lower than Medtronic BI-HRIM (P = 0.003). Overall, BI-HRIM correlated with MNBI at corresponding recording sites, 7 cm and 9 cm (P < 0.05), but not at other sites (P ≥ 0.19). Pearson’s correlations > 0.5 were seen at MNBI at 7 cm for both systems, and at 9 cm for Medtronic. DBI-HRIM correlated with MNBI at 3 cm and 5 cm (P < 0.03), but not at other locations (P > 0.1). Conclusions While numeric differences exist between manufacturers, BI-HRIM correlates with MNBI from corresponding channels in patients with physiologic AET. Comparison with AET elevation is needed to determine correlations between pathologic MNBI with BI-HRIM across manufacturers. The optimal HRIM channels from which BI values should be extracted also warrants further study. (J Neurogastroenterol Motil 2020;26:455-462)
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