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Rahimizadeh, Mohammad,Eshghi, Hossein,Shiri, Ali,Ghadamyari, Zohreh,Matin, Maryam M.,Oroojalian, Fatemeh,Pordeli, Parvaneh Korean Chemical Society 2012 대한화학회지 Vol.56 No.6
Diazo coupling reactions of aromatic amines with 2-naphthol in a green, efficient and easy procedure is described. Ferric hydrogensulfate catalyses this reaction in water at room temperature and short reaction time with high yields. The antibacterial activities of the synthesized compounds against four pathogenic bacteria are also investigated.
Albumin: An Emerging Opportunity in Drug Delivery
Parastou Rahimizadeh,양성태,임성인 한국생물공학회 2020 Biotechnology and Bioprocess Engineering Vol.25 No.6
Albumin, the most abundant and long-lived serum protein, exhibits novel features as a carrier that can greatly enhance the pharmacological action of therapeutic payloads. Besides passive trafficking by enhanced permeability and retention effect, albumin has been shown to accumulate within the tumor environment or inflamed tissues by receptor-mediated active transport, lending itself to being a promising scaffold for targeted drug delivery. Albumin has recently been found to be a scavenger for amyloid-β with the potential to treat neurodegenerative diseases. The hydrophobic binding pockets, conjugatable thiol residue, and surface-exposed N- and C-termini in albumin inherently serve as useful spots for carrying various kinds of peptidyl and non-peptidyl drugs. Beyond its long-standing role as a half-life extender, albumin is emerging as a versatile drug carrier to aid numerous therapeutic agents that have poor pharmacokinetics, targetability, solubility, and instability in vivo.
Bakavoli, Mehdi,Rahimizadeh, Mohammad,Eshghi, Hossein,Shiri, Ali,Ebrahimpour, Zahra,Takjoo, Reza Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.4
A new and efficient reagent for the conversion of primary and secondary alcohols into their corresponding aldehydes and ketones is introduced. The reagent was easily prepared from the reaction of DBU with molecular bromine in $CHCl_3$. The structure of the reagent as $DBUH^+{Br_3}^-$ was determined by single crystal X-ray diffraction analysis.
Eshghi, Hossein,Rahimizadeh, Mohammad,Shiri, Ali,Sedaghat, Parisa Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.2
A series of substituted benzimidazoles and benzothiazoles were prepared through the one-pot reaction of ophenylenediamine and o-aminothiophenol with various aldehydes in the presence of ferric hydrogensulfate both in EtOH and water as solvent. The reactions proceed smoothly in excellent yield, high chemoselectivity and with an easy work-up.
Hossein Eshghi,Mohammad Rahimizadeh,Ali Shiri,Parisa Sedaghat 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.2
A series of substituted benzimidazoles and benzothiazoles were prepared through the one-pot reaction of ophenylenediamine and o-aminothiophenol with various aldehydes in the presence of ferric hydrogensulfate both in EtOH and water as solvent. The reactions proceed smoothly in excellent yield, high chemoselectivity and with an easy work-up.