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      • Slide Session : OS-IFD-08 ; Infectious Disease : West Nile Virus (WNV) as a Potential New Threat to HIV/AIDS Patients in Indonesia

        ( Nasronudin ),( Bimo Aksono ),( Bimo D Lukito ),( Brian E Rachman ),( Noordiansyah ),( Retno Indrawati ),( Retno P Rahayu ),( M Inge Lusida ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        NASRONUDIN1, Bimo AKSONO1, Bimo D LUKITO4, Brian E RACHMAN2, NOORDIANSYAH7, Retno INDRAWATI1, Retno P RAHAYU1, M Inge LUSIDA1 Institute of Tropical Disease, Airlangga University, Indonesia1, Medical Faculty Airlangga University - Dr Soetomo Hospital, Indonesia2, Medical Faculty Airlangga University - Dr Soetomo Hospital, Indonesia3, Medical Faculty Airlangga University - Dr Soetomo Hospital, Indonesia4, Faculty of Dentistry, Airlangga University, Indonesia5, Faculty of Dentistry, Airlangga University, Indonesia6, Airlangga University Hospital, Indonesia7 Background: WNV is a mosquito-borne zoonotic arbovirus, belongs to the genus Flavivirus in the family Flaviviridae. Although WNV infection in human has been reported for decades in several parts of the world, but it was diagnosed recently in 2014 in Indonesia. Approximately 80% of WNV infections in humans do not develop any symptoms. Elderly or those with immunosuppression, such as HIV/AIDS, are at greater risk for serious illness. Phylogenetic analysis has divided WNV into mainly Lineage 1(L1) and Lineage 2 (L2), which is geographically specifi c. Aims: To determine and phylogenetic analyse of WNV on HIV/AIDS Patients. Methods: The subjects were HIV/AIDS patients in Airlangga University Hospital. Examination of blood samples were performed in Institute of Tropical Disease Airlangga University. This study has been approved by Ethical Committee. A total of 30 HIV/ AIDS patients were enroled after obtainined informed consent, and examined for WNV RNA using RT-PCR in the envelope region (408 bps). Results: The results showed that 8 (25.81%) of 30 HIV/AIDS patients were WNV positive. The phylogenetic of one WNV strain in this study showed that it belongs to the L2. Only recently were those strains of L2 identifi ed outside of Africa. Conclusions: We found WNV as one of the potential coinfections in HIV/AIDS patients in Indonesia, and therefore it may in other countries too. Phylogenetic analysis of one strain revealed that the virus clustered in the lineage 2.

      • Separation of Intrinsic and Scattering Attenuation Using Single Event Source in South Korea

        Rachman, Asep Nur,Chung, Tae Woong,Yoshimoto, Kazuo,Son, Busoon Seismological Society of America 2015 Bulletin of the Seismological Society of America Vol.105 No.2

        <P>Simultaneous use of numerous events in the multiple lapse time window analysis (MLTWA) method is the most effective way to obtain [Formula] and [Formula] values. Such simultaneous use of numerous events normally shows a large observational scatter, which may be caused by different radiation pattern and focal depth of each earthquake, and regional alteration of the local structure. To avoid these scattering factors, the current study attempted to use single event source as the input data in MLTWA for South Korea. The direct simulation Monte Carlo (DSMC) method was used to simulate the observations, which showed realistic results when the number of recorded stations was eight or more. The obtained values of seismic albedo (<I>B</I><SUB>0</SUB>) were less than 0.5, which were in accordance with the same in the previous results. Three envelopes constructed by combination of three regional values of [Formula] at 1 Hz produced regional variations, of which the ones at high frequencies of [Formula] and at low frequencies of [Formula] were remarkable. This result, showing the local variation indicated an advantage of the study using single source event over the previous studies in South Korea that involved extensively distributed data. Because DSMC was known to be applicable to 3D structure due to its simple algorithm, the current study also tried to correct radiation pattern of the observations by inserting focal mechanism algorithm to the code of the DSMC method. Such insertion, however, generated extremely low values of [Formula] because the geometrically shrunk receiver could not capture most of the scattered particles. This receiver problem is most likely to be a major obstacle of the 3D study of DSMC. In addition, the significant depth effect of <I>Q</I><SUP>−1</SUP> was identified for the prior MLTWA studies resulting from different measurement range and focal depth.</P>

      • Multiple lapse time window analysis using solely single events in South Korea

        Rachman, Asep Nur,Chung, Tae Woong,Chung, Kyung-Hoon ASEG PUBLICATIONS 2017 EXPLORATION GEOPHYSICS -AUSTRALIA- Vol.48 No.4

        <P>Scattering (Q(s)(-1)) and intrinsic (Q(i)(-1)) attenuation, important parameters for inferring both the materials and the physical condition of the regional lithosphere, are generally separated by the method of multiple lapse time window analysis (MLTWA). Recently, depth variation of crustal Q(s)(-1) and Q(i)(-1) by applying single events to MLTWA was first shown; however, this application inevitably combined several events due to insufficient data caused by a window with limited range. In this study, we demonstrated that a flexible range window can be applied successfully to solely single events in MLTWA. In particular, a more reliable constraint was obtained than in the previous study, with a reduced amount of data. This technique may be particularly useful for seismically stable regions due to the limitation of available combinations of similar depth events.</P>

      • Poster Session : PS 0397 ; Infectious Disease ; Analysis of Japanese Encephalitis Virus (JEV) as Trigger for Secondary Infection in HIV/AIDS Patients in Indonesia

        ( Brian Eka Rachman ),( Retno P Rahayu ),( Nasronudin Nasronudin ),( Noordiansyah Noordiansyah ),( Bimo D Lukito ),( Retno Indrawati ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: The HIV infection is associated with immunecompromised and rising in opportunistic infection. Therefore, it is predicted that death caused by HIV/AIDS would increase. The main problem for HIV/AIDS patients are opportunistic infection caused by Japanese Encephalitis (JEV) which is rarely found and diffi cult to diagnosed in Indonesia nowadays. Methods: This study is an observational descriptive. Cross sectional technique was used in this study. The amount of samples were 30 HIV/AIDS patients. Enzyme-linked Immunosorbent Assay (ELISA) was used to test IgG and IgM, and Real Time Polimerase chain reaction (RT-PCR). The sample was obtained from HIV/AIDS patients` blood, then CD4 and viral load were tested to detect JEV secondary infection. Results: There were 93,54% of HIV/AIDS patients have undergone ARV therapy for 1-3 years. HIV/AIDS is mostly sexually transmitted with 67,74%. The distribution of HIV/AIDS patients in stage I is 41,94%, 35,48% in stage II, and 22,58% in stage III. The HIV>4x102 viral load test revealed 20% of the samples are infected by JEV. The intention of MDGs (Millenium Development Goals) is to achieve no new infection, no discrimination, no death associated to AIDS are expected to contribute in order to decrease death through early detection of secondary infection. This study might be used as new policies in impeding HIV/AIDS, so the MDGs target could be reached. Conclusions: This research shows that ARV therapy is not enough to prevent secondary infection, such as JEV in HIV/AIDS patients. Therefore, it is necessary to give antimicrobes therapy and adequate nutrional supports.

      • KCI등재

        Bank-specific Factors Affecting Non-performing Loans in Developing Countries: Case Study of Indonesia

        Rathria Arrina Rachman,Yohanes Berenika Kadarusman,Kevin Anggriono,Robertus Setiadi 한국유통과학회 2018 The Journal of Asian Finance, Economics and Busine Vol.5 No.2

        In recent decades, financial crises in various countries have often been preceded by the rise in non-performing loans (NPLs) in the banks’ asset portfolios. The increase in NPLs is proven to have adverse impact on the banking sector so that understanding the determinant of NPLs is immensely crucial to ensure the efficiency and soundness of the overall economy. This study aims to shed light on bank-specific factors that affect loan default problems in developing countries whose banking sectors play a major role in the overall economy. This study analyzes panel data sets of 36 commercial banks listed in the Indonesian Stock Exchange during the period 2008–2015. Applying fixedeffects panel regression model reveals that Indonesian banks’ profitability and credit growth negatively influence the number of NPLs. Moreover, banks with higher profitability are proven to have lower NPLs because they can afford adequate credit management practices. Likewise, banks with higher credit growth evidently have lower NPLs in the sense that they demonstrate more specialized lending activity and thus have better credit management systems. These findings imply that, in order to lower loan defaults that can deteriorate banks’ asset quality, banks should maintain their level of profitability and increase, rather than decrease, their credit supply to debtors.

      • KCI등재

        Stabilization and solidification of tailings from a traditional gold mine using Portland cement

        Ranno Marlany Rachman,Ayi Syaeful Bahri,Yulinah Trihadiningrum 대한환경공학회 2018 Environmental Engineering Research Vol.23 No.2

        The traditional gold mining in Kulon Progo district, Special Region of Yogyakarta Province produced tailings containing mercury (Hg) from the gold amalgamation process. Mercury accumulated in tailings has 164.19 mg/kg - 383.21 mg/kg in total concentration. Stabilization/solidification (S/S) is one of the remediation technologies to reduce waste pollution. Portland cement is one of the additive materials in S/S that effective encapsulates heavy metal waste. The aim of this research is to know the optimum composition of tailings mixture with Portland cement in S/S process. This research used variation of tailings composition. Variation of Portland cement composition with tailing are 100:0, 90:10, 80:20, 70:30, 60:40, 50:50, 40:60, 30:70, 20:80 and 10:90. The result of this study found that the optimum composition of Portland cement: tailings was 10:90, with compression test of 257 ton/㎡ and TCLP test was 0.0069 mg/L. The compression test results were in accordance to US EPA Standard quality of 35 ton/㎡. TCLP test results meet the standard of Indonesian Government Regulation No. 101 Year 2014 of 0.05 mg/L.

      • Slide Session : OS-IFD-05 ; Infectious Disease : Displacement of the Predominant Dengue Virus from Type 2 to Type 1 in Surabaya, Indonesia Within March 2012 - April 2013

        ( Brian Eka Rachman ),( Maria I Lusida ),( E Bimo Aksono ),( Siswanto Siswanto ),( Musofa Rusli ),( Bramantono ),( Nasronudin ),( Umar F Achmadi ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Indonesia is a country with high endemicity of dengue (haemorrhagic) fever (DF/ DHF). It was reported that dengue virus type 2 (DENV2) was the predominant circulating virus in 2003-2005 in Surabaya, Indonesia, while Yamanaka et al., 2011 reported shifting of DENV serotypes between 2008 - 2010 in three times survey. This study was part of the clinical trial phase three of antivirus against dengue, held in year 2012-2013. Methods: A total of 317 serum samples were collected from patients with fever on day-1 or day-2, suspected dengue infection according to WHO criteria, showed positive result either by NS-1, and or IgM - IgG within March 2012 - April 2013. After an RNA extraction, a multiplex DEN 1-4 quantitative Real-Time PCR was applied to each sample. Results: Sixty three (90%) of 70 PCR positive sera collected within March 2012 and May 2012 showed DENV2, then 5(7.2%) DENV1, 1(1.4%) DENV3, and 1mixed of DENV1+3. Surprisingly, it was totally different for those collected since June 2012 until April 2013. Fifty three (50%) of 106 positive samples were DENV1, 5 (4.7%) DENV2, 35 (33%) DENV3, 7 (6.6%) DEN4, and 2, 2, 1 mixed type of DENV 1+3, DENV1+4, DENV 3+4 respectively. Conclusions: There was a displacement of the predominant type of dengue virus circulating in Surabaya within March 2012 - April 2013. Such kind of predominant DENV shifting from type 2 to type 1 has occurred between October and November 2008. This indicates the need for continuous surveillance of the circulating viruses, which may predict the risk of severe DHF and mild DF as reported previously.

      • SCOPUS

        Recent Development of a 36 meter Small-Angle Neutron Scattering BATAN Spectrometer (SMARTer) in Serpong Indonesia

        Putra, Edy Giri Rachman,Bharoto,Seong, Baek Seok Institute of Physics 2010 Journal of Physics: Conference Series Vol.247 No.1

        <P>The 36 meter small-angle neutron scattering (SANS) spectrometer BATAN (SMARTer) in Serpong, Indonesia has been revitalised for several years. The work on replacing, upgrading and improving the control system and the experimental method were conducted in order to setup the spectrometer back in operation. Two main personal computers, one for handling and controlling the mechanical system and another one for acquiring neutron data were employed at the spectrometer. The standard and established SANS data reduction and analysis programs, such as GRASP and NIST Igor have been implemented to subtract the raw scattered neutron data with the backgrounds and then analyse the corrected data. The scattering data of ferrofluids samples, Fe<SUB>3</SUB>O<SUB>4</SUB> and MnZnFe<SUB>2</SUB>O<SUB>4</SUB> have been obtained using SANS spectrometers in BATAN Serpong, Indonesia and HANARO-KAERI, Republic of Korea for inter-laboratory comparison and investigation of proposed research interest. The results were comparable from both scattering data analysis.</P>

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