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Seismic assessment of steel structures through a cumulative damage
R. Perera,S. Gómez,E. Alarcón 국제구조공학회 2001 Steel and Composite Structures, An International J Vol.1 No.3
In the present work a constitutive model is developed which permits the assessment of the structural performance through a criterion based on cumulative damage. For it, a damage index is defined and is evaluated through the application of the Miner’s rule in low-cycle fatigue. However, the damage index is not considered as a posteriori variable since is incorporated explicitly as an internal variable in the constitutive equations which produces a direct coupling between the damage and the structural mechanical behaviour allowing the possibility of considering as a whole different coupled phenomena. For the elaboration of this damage model, the concepts of the mechanics of continuum medium are applied on lumped dissipative models in order to obtain a coupled simplified model. As a result an elastoplastic model coupled with damage and fatigue damage is obtained.
Design of a Track-Leg Hybrid Locomotive Mobile Robot
K. N. M. Perera,D. L. F. M. Liyanage,P. V. K. Asanka,D. N. Rajapaksha,Y. W. R. Amarasinghe,R. A. R. C. Gopura,S. A. Nanayakkara 제어로봇시스템학회 2020 제어로봇시스템학회 국제학술대회 논문집 Vol.2020 No.10
The use of robotic platforms for operations in harsh and high risk environments such as mining sites has become more popular with the advancements within the field of mobile robotics. In this paper, the designing of a hybrid locomotive mobile platform that utilizes both tracked locomotion and legged-like movements to achieve mobility is presented. The proposed track-leg mechanism and power transmission methodology are discussed in detail along with the overall design framework. The functionality validation and analysis of the legged locomotion was done in a simulation environment using MSC ADAMS with open-loop track-leg velocity control. The designed mobile robot demonstrated the ability to traverse a flat terrain and overcome a semi-cylindrical obstacle without tipping over in the simulations for the selected gait. The mobile robot also consists of 3 degrees of freedom (DOF) robotic arm which facilitates total human replacement by enabling the ability to perform any sample collecting, inspecting, pick and place tasks. The design of the robotic arm is also presented within this paper.
Godahewa, G.I.,Perera, N.C.N.,Elvitigala, D.A.S.,Jayasooriya, R.G.P.T.,Kim, G.Y.,Lee, J. Academic Press 2016 Fish & Shellfish Immunology Vol.57 No.-
1-cysteine peroxiredoxin (Prx6) is an antioxidant enzyme that protects cells by detoxifying multiple peroxide species. This study aimed to describe molecular features, functional assessments and potential immune responses of Prx6 identified from the big-belly seahorse, Hippocampus abdominalis (HaPrx6). The complete ORF (666 bp) of HaPrx6 encodes a polypeptide (24 kDa) of 222 amino acids, and harbors a prominent peroxiredoxin super-family domain, a peroxidatic catalytic center, and a peroxidatic cysteine. The deduced amino acid sequence of HaPrx6 shares a relatively high amino acid sequence similarity and close evolutionary relationship with Oplegnathus fasciatus Prx6. The purified recombinant HaPrx6 protein (rHaPrx6) was shown to protect plasmid DNA in the Metal Catalyzed Oxidation (MCO) assay and, together with 1,4-Dithiothreitol (DTT), protected human leukemia THP-1 cells from extracellular H<SUB>2</SUB>O<SUB>2</SUB>-mediated cell death. In addition, quantitative real-time PCR revealed that HaPrx6 mRNA was constitutively expressed in 14 different tissues, with the highest expression observed in liver tissue. Inductive transcriptional responses were observed in liver and kidney tissues of fish after treating them with bacterial stimuli, including LPS, Edwardsiella tarda, and Streptococcus iniae. These results suggest that HaPrx6 may play an important role in the immune response of the big-belly seahorse against microbial infection. Collectively, these findings provide structural and functional insights into HaPrx6.
MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea, 2015
Choe, Pyoeng Gyun,Perera, R.A.P.M.,Park, Wan Beom,Song, Kyoung-Ho,Bang, Ji Hwan,Kim, Eu Suk,Kim, Hong Bin,Ko, Long Wei Ronald,Park, Sang Won,Kim, Nam-Joong,Lau, Eric H.Y.,Poon, Leo L.M.,Peiris, Malik U.S. Department of Health and Human Services * Cen 2017 Emerging Infectious Diseases Vol.23 No.7
<P>We investigated the kinetics of the Middle East respiratory syndrome coronavirus (MERS-CoV) neutralizing and spike protein antibody titers over the course of 1 year in 11 patients who were confirmed by reverse transcription PCR to have been infected during the outbreak in South Korea in 2015. Robust antibody responses were detected in all survivors who had severe disease; responses remained detectable, albeit with some waning, for <U><</U>1 year. The duration of viral RNA detection (but not viral load) in sputum significantly correlated with the antibody response magnitude. The MERS S1 ELISA antibody titers correlated well with the neutralizing antibody response. Antibody titers in 4 of 6 patients who had mild illness were undetectable even though most had evidence of pneumonia. This finding implies that MERS-CoV seroepidemiologic studies markedly underestimate the extent of mild and asymptomatic infection. Obtaining convalescent-phase plasma with high antibody titers to treat MERS will be challenging.</P>
S Medawela Disanayaka,P Sedrick,R Widyalankarae,H Perera,P Medagama 국제이네비해양경제학회 2022 International Journal of e-Navigation and Maritime Vol.18 No.1
This study introduces the Three-Memory-Model (Cherry, 2019) in education into Maritime Simulator- based training in Sri Lanka and conducts empirical research. In simulator-based education what is disseminated as knowledge during the Briefing, Scenario and Debriefing phases must be transferred from short-term, across working memory to long-term-memory. Working memory gained during the scenario phase, could be encoded into long-term-memory through rehearsal probes. But the number of probes which could be tolerated by the participants of simulator-based training has not undergone empirical investigation. Thus, selecting the Open Sea scenario phase as its setting the research questions aim to identify tolerance limits in the participants for the number of freezes and the number of probes introduced during each freeze. The methodology selects a population of seafarers (n = 60). Through stratified random sampling this population was subdivided based on experience at sea as Group A (n = 30): Mean of 2 years and Group B (n = 30): Mean of 13.6 years of sea experience. The duration of the open sea scenario phase is 35 minutes with freezes at 10-minute intervals. The number of probes were given a range of 7 to. Data analysis utilized SPSS. The highest percentage mean value was obtained for three freezes for the Open Sea scenario phase while two freezes had the next highest percentage mean value. The mean value of the tolerance limits for questions during one freeze is approximately 9 and 6 probes for Group A and B respectively. Citing prior research on working memory, visuo-spatial vs. verbal working memory, reaction time and age this study raises a counter argument against the findings: the self-declared tolerance limits of the number of questions the participants feel comfortable to answer during each freeze. The findings of this research are valuable to maritime Simulator-based instructional designers outside and within Sri Lanka.
The effect of gender on willingness to pay for mass customised running shoes
Kalantari Hassan Daronkola,Johnson Lester W,Perera Chamila R. 한국마케팅과학회 2021 Journal of Global Fashion Marketing Vol.12 No.2
We investigate whether gender and different levels of customisation have a significant effect on consumers’ willingness to purchase mass customised running shoes. An online panel survey was utilised to collect data from 353 Australian adults who wear running shoes at least once a month. Three attributes – degree of customisation, price, and delivery time were utilised in the data analysis to explore willingness to pay for customised shoes. Informed by conjoint analysis and t-tests, the study makes a significant theoretical contribution by extending the understanding of inconveniences of mass customisation from the perspective of customers’ willingness across genders. It is found that for women, degree of customisation and delivery time are the most important attributes, while for men, price and degree of customisation are the more crucial attributes. Female customers are more willing to purchase the product than male customers. The study addresses the research gap that is how differently females and males who usually have different sensory perceptions respond to masscustomised products. Further, the study provides valuable strategic insights for both manufacturers and marketers to cater fragmented consumer markets through mass customisation by identifying subtle differences in customer readiness among their target group of customers.