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      • Aflatoxin Contamination of Red Chili Pepper From Bolivia and Peru, Countries with High Gallbladder Cancer Incidence Rates

        Asai, Takao,Tsuchiya, Yasuo,Okano, Kiyoshi,Piscoya, Alejandro,Nishi, Carlos Yoshito,Ikoma, Toshikazu,Oyama, Tomizo,Ikegami, Kikuo,Yamamoto, Masaharu Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

        Chilean red chili peppers contaminated with aflatoxins were reported in a previous study. If the development of gallbladder cancer (GBC) in Chile is associated with a high level of consumption of aflatoxin-contaminated red chili peppers, such peppers from other countries having a high GBC incidence rate may also be contaminated with aflatoxins. We aimed to determine whether this might be the case for red chili peppers from Bolivia and Peru. A total of 7 samples (3 from Bolivia, 4 from Peru) and 3 controls (2 from China, 1 from Japan) were evaluated. Aflatoxins were extracted with acetonitrile:water (9:1, v/v) and eluted through an immuno-affinity column. The concentrations of aflatoxins B1, B2, G1, and G2 were measured using high-performance liquid chromatography (HPLC), and then the detected aflatoxins were identified using HPLC-mass spectrometry. In some but not all of the samples from Bolivia and Peru, aflatoxin B1 or aflatoxins B1 and B2 were detected. In particular, aflatoxin B1 or total aflatoxin concentrations in a Bolivian samples were above the maximum levels for aflatoxins in spices proposed by the European Commission. Red chili peppers from Bolivia and Peru consumed by populations having high GBC incidence rates would appear to be contaminated with aflatoxins. These data suggest the possibility that a high level of consumption of aflatoxin-contaminated red chili peppers is related to the development of GBC, and the association between the two should be confirmed by a case-control study.

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        Impact of COVID-19 on Endoscopy Training: Perspectives from a Global Survey of Program Directors and Endoscopy Trainers

        Shivakumar Vignesh,Amna Subhan Butt,Mohamed Alboraie,Bruno Costa Martins,Alejandro Piscoya,Quang Trung Tran,Damien Tan Meng Yew,Shahriyar Ghazanfar,Pezhman Alavinejad,Edna Kamau,Ajay M Verma,Robin B M 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.5

        Background/Aims: The coronavirus disease of 2019 (COVID-19) pandemic has impacted the training of medical traineesinternationally. The aim of this study was to assess the global impact of COVID-19 on endoscopy training from the perspective ofendoscopy trainers and to identify strategies implemented to mitigate the impact on trainee education. Methods: Teaching faculty of gastroenterology (GI) training programs globally were invited to complete a 36-question web-basedsurvey to report the characteristics of their training programs and the impact of COVID-19 on various aspects of endoscopytraining, including what factors decisions were based on. Results: The survey response rate was 52.6% (305 out of 580 individuals); 92.8% reported a negative impact on endoscopy training,with suspension of elective procedures (77.1%) being the most detrimental factor. Geographic variations were noted, with Europeanprograms reporting the lowest percentage of trainee participation in procedures. A higher proportion of trainees in the Americaswere allowed to continue performing procedures, and trainers from the Americas reported receiving the greatest support forendoscopy teaching. Conclusions: This study demonstrated that the COVID-19 pandemic has had a significant negative impact on GI endoscopytraining internationally, as reported by endoscopy trainers. Focus-optimizing endoscopy training and assessment of competenciesare necessary to ensure adequate endoscopy training.

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