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      • Poster Session:PS 0189 ; Endocrinology : High Normal TSH Levels Association with Metabolic Syndrome Components in Type 2 Diabetic Patients

        ( Petrosyan L ),( Kyu Yeon Hur ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Objective: Obesity and insulin resistance are key features of the metabolic syndrome (MetS). The purpose of our study was to compare MetS components association with low normal and high normal TSH levels in type 2 diabetic patients and to access diabetes control in patients with high-normal TSH levels. Methods: A total of 120 subjects who met metabolic syndrome by NCEP - ATP III criteria were recruited for this study from November 2012 to June 2014 .Subjects were included in the study with TSH values between 0.3 and 4.5 mU/l, who did not take any thyroid medication and had a similar iodine diet. The study subjects were weighed and their anthropometric indices were taken. Lipid parameters, fasting plasma glucose, HbA1c, eGFR, blood pressure (BP) were documented, and TSH were measured by an electrochemiluminescence immunoassay. Statistical analysis was performed by using SPSS 18(P value <0.05 was considered signifi cant). Results: Serum TSH levels were significantly and positively associated with BMI, systolic and diastolic BP, serum triglyceride and HbA1c levels, whereas negatively with eGFR. Subjects with a TSH in a higher normal range (2.5-4.5mU/I, n=58) had a signifi cantly higher BMI (26.7±3 vs. 24.1±2.7 adjusted for age and sex (P < 0.001). The research shows, that when TSH is in low normal range, the number of patients with non- compensated diabetes (HbA1c >7%) decreases from 27.5% to 12.5% (P = 0.02, adjusted for age and sex). In addition, we found no association between TSH levels and medications used for the treatment of diabetes, dyslipidemia and hypertension. Conclusion: High normal TSH levels were signifi cantly associated with components of metabolic syndrome in type 2 diabetic subjects. Number of patients with non-compensated diabetes increased when TSH was in high-normal range. We suggest low normal TSH concentrations in insulin-resistant subjects with high risk of developing cardiovascular disease.

      • SCIESCOPUSKCI등재

        NORMAL WEIGHTED BERGMAN TYPE OPERATORS ON MIXED NORM SPACES OVER THE BALL IN ℂ<sup>n</sup>

        Avetisyan, Karen L.,Petrosyan, Albert I. Korean Mathematical Society 2018 대한수학회지 Vol.55 No.2

        The paper studies some new ${\mathbb{C}}^n$-generalizations of Bergman type operators introduced by Shields and Williams depending on a normal pair of weight functions. We find the values of parameter ${\beta}$ for which these operators are bounded on mixed norm spaces L(p, q, ${\beta}$) over the unit ball in ${\mathbb{C}}^n$. Moreover, these operators are bounded projections as well, and the images of L(p, q, ${\beta}$) under the projections are found.

      • KCI등재

        Normal weighted Bergman type operators on mixed norm spaces over the ball in $\mathbb C^n$

        Karen L. Avetisyan,Albert I. Petrosyan 대한수학회 2018 대한수학회지 Vol.55 No.2

        The paper studies some new $\mathbb C^n$-generalizations of Bergman type operators introduced by Shields and Williams depending on a normal pair of weight functions. We find the values of parameter $\beta$ for which these operators are bounded on mixed norm spaces $L(p,q,\beta)$ over the unit ball in $\mathbb C^n$. Moreover, these operators are bounded projections as well, and the images of $L(p,q,\beta)$ under the projections are found.

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