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- 저자 : Paula de Paula Menezes Barbosa (검색결과 2 건)
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Comparison of different Brazilian citrus by-products as source of natural antioxidants
Paula de Paula Menezes Barbosa,Amanda Roggia Ruviaro,Gabriela Alves Macedo 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.5
Significant amounts of citrus by-products remain after juice processing, which is then used to obtain pectin. The pectin industry then generates a new waste. No study has characterized this residue or suggested applications for it. The main goal of this study was to compare citrus industrial by-products that remain after juice (CJB) and pectin (CPB) extraction, aiming to obtain bioactive compounds. The residues were evaluated for their chemical composition, antioxidant capacity, and polyphenols content. CJB had 2-fold higher total phenols than CPB. Moreover, CJB exhibited higher antioxidant capacity than CPB. Nine polyphenols were detected; hesperidin was the main compound on both residues. CPB had higher content of polyphenols than CJB, which can be attributed to the industry procedure of pectin extraction. Thus, this study provides support for the reuse of CPB to obtain nutraceutical compounds, converting waste into added-value products.
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Antidiabetic Effect of the Chrysobalanus icaco L. Aqueous Extract in Rats
Ana Paula de Oliveira Barbosa,Gabriela de Oliveira Silveira,Igor Alexandre Cortes de Menezes,Jose´ Melquiades Rezende Neto,Jose´ Leal C. Bitencurt,Charles dos Santos Estavam,Amanda do Carmo Bion de Li 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.6
Chrysobalanus icaco L. is a medicinal plant popularly known in Brazil as ‘‘Grageru’’ or ‘‘Abageru.’’ It is used in African and American continents as medicinal food in the treatment of several diseases, including diabetes. This study used phytochemical screening to determine the antioxidant and α-amylase inhibitor activities of the aqueous extract (AECI) of C. icaco, and evaluated its antidiabetic potential in rodents. Phytochemical screening was performed using colorimetric tests with specific reagents. The in vitro antioxidant activity was evaluated by the scavenging activity of 2,2-diphenyl-1-picril-hydrazyl. The lethality test and behavioral screening was performed using an oral administration of 5 g/kg of AECI. The antidiabetic potential of AECI was evaluated through the oral glucose tolerance test (OGTT) and chronic hypoglycemic test at the doses of 100, 200, and 400 mg/kg (orally). Metformin was used as a reference drug in all tests. Diabetes was induced by injection of alloxan (40 mg/kg; intravenously). Phytochemical screening showed the presence of various compounds, including tannins, flavones, triterpenoids, steroids, saponins, and alkaloids. The in vitro antioxidant test demonstrated that AECI presented potent antioxidant activity. The lethality test and behavioral screening did not show lethality signs. In the OGTT test, AECI administration was not able to inhibit the elevation of glycemia. However, chronically administrated, it was able to cause a significant (P < .05) reduction of glycemia from 335 ± 27 up to 197 ± 15 mg/dL. These results demonstrate that the AECI presents a potential beneficial effect for diabetes.
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