Expansion to the Motion Sickness Susceptibility Questionnaire-Short Form: A Cross-Sectional Study

Ugur Emel,Konukseven Bahriye Ozlem,Topdag Murat,Cakmakci Mustafa Engin,Topdag Deniz Ozlem 대한청각학회 2022 Journal of Audiology & Otology Vol.26 No.2

Background and Objectives: The primary objective of this study is to investigate the necessity of questioning virtual reality systems in the motion sickness susceptibility questionnaire (MSSQ)-short form. The secondary objective of this study is to determine the validity and reliability of the Turkish version of the MSSQ-short form, with proven validity and reliability.Subjects and Methods: In the questionnaire form, for which expert opinion was obtained to maintain linguistic equivalence, the virtual reality items were added to the questionnaire. The questionnaire was then administered to 297 individuals. The results were statistically analyzed with and without these virtual reality items for validity and reliability.Results: After the addition of the virtual reality items, the reliability of the questionnaire was found to be quite high (Cronbach’s alpha r=0.912). The norm values between the original MSSQ-short form (12.9±9.9) and the Turkish MSSQ-short form (13.8±12.9) were found to be consistent.Conclusions: Motion sickness symptoms can occur not only during movement, but also with indirect stimulus. Our findings suggest that adding virtual reality items to the original form is important in long term practical applications. Our results show that the Turkish version of the original questionnaire is quite reliable. Submission of the MSSQ-short form in Turkish will be useful for documentation and will also encourage further research in this area.

Responsibilities and Difficulties of Caregivers of Cancer Patients in Home Care

Ugur, Ozlem,Elcigil, Ayfer,Arslan, Deniz,Sonmez, Ayfer Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Background: Having been known as a virulent disease in 1970s, cancer is now onsidered a chronic disease and 64% of cancer patients live for five years after diagnosis. Home care has gradually gained more importance and it is a great burden on the shoulders of caregivers. Caregivers have to undertake the responsibility of the cancer patient's home management, and organize care and arrange health care services according to the ever-changing condition of patients. Caregivers should be prepared for home care so they can provide accurate and complete care to patients. This descriptive study aims to investigate challenges that caregivers encounter in the home care of patients and the reasons for these challenges. Materials and Methods: The research group consisted of caregivers of outpatients in a daily treatment center in a university hospital. The research sampling consisted of 137 voluntary caregivers of patients who attended the Daily Treatment Center for control, chemotherapy or other supportive cares services between January-June, 2011. Data were collected with face-to-face interviews in the Daily Treatment Center. Ethics Committee approval was taken university hospital; caregivers and their patients were informed about the research and their approval was taken as well. Results: It was found that 54.01% of caregivers help patient's nutrition, 50.36% help medicine use, 26.28% help oral hygiene, 26.28% help to meet urinary needs and 51.82% help to change clothes, 69.34% of caregivers help to change bed sheets, 38.69% help the patient to communicate with their environment and 71.53% help to bring the patient to hospital or outside. Conclusions: This study, it was found that caregivers experience challenges due to following factors: patient nutrition, medicine use, oral and body hygiene, colostomy maintenance and stomach tube feeding, concern of dropping the patient, feeling incompetency in body temperature and fever control, fatigue, and lack of personal time.

Barbed sutures versus conventional tenorrhaphy in flexor tendon repair: An ex vivo biomechanical analysis

Colak, Ozlem,Kankaya, Yuksel,Sungur, Nezih,Ozer, Kadri,Gursoy, Koray,Serbetci, Kemal,Kocer, Ugur Korean Society of Plastic and Reconstructive Surge 2019 Archives of Plastic Surgery Vol.46 No.3

Background The management of flexor tendon injuries has evolved in recent years through industrial improvements in suture materials, refinements of repair methods, and early rehabilitation protocols. However, there is no consensus on the ideal suture material and technique. This study was conducted to compare the tensile strength, repair time, and characteristics of 4-strand cruciate, modified Kessler, and 4-strand horizontal intrafiber barbed sutures for flexor tenorrhaphy with a 12-mm suture purchase length in an animal model. Methods The right third deep flexors of 60 adult Leghorn chicken feet were isolated and repaired with a 12-mm suture purchase length. The tendons were randomly assigned to three groups of equal number (n=20 each). Groups 1 and 2 received 4-strand cruciate and modified Kessler repair with conventional suture materials, respectively. A 4-strand horizontal intrafiber barbed suture technique was used in group 3. The repaired tendons were biomechanically tested for tensile strength, 2-mm gap resistance, and mode of failure. Repair times were also recorded. Results The maximum tensile strength until failure was $44.6{\pm}4.3N$ in group 1, $35.7{\pm}5.2N$ in group 2, and $56.7{\pm}17.3N$ in group 3. The barbed sutures were superior to the other sutures in terms of the load needed for 2-mm gap formation (P<0.05). Furthermore, the barbed sutures showed the shortest repair time (P<0.05). Conclusions This study found that 4-strand horizontal intrafiber barbed suture repair with a 12-mm purchase length in a chicken flexor tendon injury model showed promising biomechanical properties and took less time to perform than other options.

Sleep Quality in Lung Cancer Patients

Akyuz, Ruveyda Gelisken,Ugur, Ozlem,Elcigil, Ayfer Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Background: The aim of this study was to determine factors affecting sleep quality of 100 patients with advanced stage lung cancer. Methods and Results: it was a descriptive study. A variety of assessment tools were used to provide sleep scores to examine the relation between adverse effects caused by the treatment (nausea, vomiting, fatigue) and sleep quality. As a result, no statistically significant relation between coughing and respiratory problems of patients, or existing depression, and average sleep quality score was found (KW:0.872, p=0.646, KW: 3.174, p=0.205, u: 441.000 p=0.916). It was revealed that nausea and loss of appetite experienced also did not affect the sleep quality score (p>0.05), whereas problems such as vomiting and fatigue did exert effects (p<0.01). Conclusions: Patients with advanced stage lung cancer suffer from sleep problems and cancer related symptoms also affect their sleep quality negatively. Nurses should plan interventions that can control symptoms such as pain, vomiting and fatigue, which affect the sleep of patients.

Developing the Scale for Quality of Life in Pediatric Oncology Patients Aged 13 – 18: Adolescent Form and Parent Form

Murat Bektas,Aslı Akdeniz Kudubes,Ozlem Ugur,Canan Vergin,Bengü Demirag 한국간호과학회 2016 Asian Nursing Research Vol.10 No.2

Purpose: This study aimed to develop the Scale for Quality of Life in Pediatric Oncology Patients Aged 13-18: Adolescent Form and Parent Form. Methods: We used the child and parent information form, Visual Quality of Life Scale, and our own scale, the Scale for Quality of Life in Pediatric Oncology Patients Aged 13-18: Adolescent Form and Parent Form. We finalized the 35-item scale to determine the items, received opinions from 14 specialists on the scale, and pilot-tested the scale in 25 children and their parents. We used Pearson correlation analysis, Cronbach a coefficient, factor analysis and receiver operating characteristics analysis to analyze the data. Results: The total Cronbach a of the parent form was .97, the total factor load was .60-.97 and the total variance was 80.4%. The cutoff point of the parent formwas 85.50. The total Cronbach a of the adolescent form was .98, the total factor load was .62-.96, and the total variance explained was 83.4%. The cutoff point of the adolescent form was 75.50. As a result of the parent form factor analysis, we determined the Kaiser-Meyer-Olkin coefficient as .83, the Barlett test X² as 12,615.92; the factor coefficients of all items of the parent form ranged from .63 to .98. The factor coefficients of all items of the adolescent form ranged from .34 to .99. As a result of the adolescent form factor analysis, we determined the KMO as .79, and the Barlett test X² as 13,970.62. Conclusions: Conclusively, we found that the adolescent form and the parent formwere valid and reliable in assessing the children's quality of life.

Developing a Scale for the Assessment of Fatigue in Pediatric Oncology Patients Aged 7-12 for Children and Parents

Kudubes, Asli Akdeniz,Bektas, Murat,Ugur, Ozlem Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

Background: This study was planned in an attempt to develop scales for the assessment of fatigue in pediatric oncology patients aged 7-12 as well as for their parents. Materials and Methods: In collecting the study data, we used the Child and Parent Information Form, Visual Fatigue Scale, Scale for the Assessment of Fatigue in Pediatric Oncology Patients Aged 7-12 and the Scale for the Assessment of Fatigue in Pediatric Oncology Patients Aged 7-12 for Parents. We also used Pearson correlation analysis, the Cronbach Alpha coefficient, Factor Analysis and ROC Analysis for the study data. Results: In this study, the total Cronbach alpha value of the parent form was 0.95, the total factor load was 0.52-0.95 and the total variance being explained was 85.7%. The cutoff point of the parent form was 82 points. The total Cronbach alpha value of the child form was 0.98, the total factor load was 0.71-0.94 and the total variance being explained was 84.7%. The cutoff point of the child form was 75 points. Conclusions: This study suggests that our scales for the assessment of fatigue in pediatric oncology patients aged 7-12 and their parents are valid and reliable instruments.

Symptom Frequency of Children with Cancer and Parent Quality of Life in Turkey

Kudubes, Asli Akdeniz,Bektas, Murat,Ugur, Ozlem Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

Background: This research was planned with the aim of determining the effect of symptom frequency of children with cancer on the quality of life of their parents. Materials and Methods: In gathering the research data, the Child and Parent Information Form, the Symptom Evaluation Form and the Family Version of Life Quality Scale in Cancer Patients were used. Evaluation was made by using percentage calculations, Kruskal Wallis test, Bonferroni adjusted t-test and Bonferroni adjusted Mann-Whitney U test. The significance level was accepted as 0.005. Results: Some 37.6% of the participant children were female and 62.4% were male, with an average age of $10.2{\pm}4.5$. While 41.0% were newly diagnosed, 46.2% were in remission and 12.8% was in relapse. Highly significant differences were detected according to the symptom frequency with parent physical and psychological health, social anxiety, and spiritual wellness sub-dimensions, as well as total point averages. Conclusions: It is thought that following up the symptoms that might develop depending on cancer diagnosis and treatment and implementing nursing initiatives aimed at reducing the symptoms, knowing the importance of life quality, maintaining measures aimed at life quality and planning initiatives to increase the life quality will play a key role in maintaining and developing the health of Turkish paediatric oncology patients and their parents.

A Tie-Over Dressing Using a Silicone Tube to Graft Deep Wounds

Cem Inan Bektas,Yuksel Kankaya,Kadri Ozer,Ruser Baris,Ozlem Colak Aslan,Ugur Kocer 대한성형외과학회 2013 Archives of Plastic Surgery Vol.40 No.6

Background The most common cause of skin graft failure is the collection of blood or serous fluid underneath the graft. In our study, we describe the use of silicone tube for tie-over dressing to secure the skin graft margins with the aim of decreasing loss of the skin graft, particularly in grafting of deep wounds. Methods Between March 2008 and July 2011, we used this technique in 17 patients with skin defects with depths ranging from 3.5 to 8 mm (mean, 5.5 mm). First, the skin graft was sutured with 3/0 silk suture material from its corners. Then, a silicone round drain tube was sutured with 3/0 absorbable polyglactin 910 over the margins of the graft. Finally, long silk threads were tied over the bolus dressing, and the tie-over dressing was completed in the usual fashion. Results The mean follow-up was 7 months (range, 2−10 months) in the outpatient clinic. Graft loss on the graft margins due to hematoma or seroma was not developed. The results of adhesion between the graft and wound bed peripherally was excellent. Conclusions In our study, we suggest that use of a silicone tube for additional pressure on the edges of skin grafts in case of reconstruction of deep skin defects.

A Tie-Over Dressing Using a Silicone Tube to Graft Deep Wounds

Bektas, Cem Inan,Kankaya, Yuksel,Ozer, Kadri,Baris, Ruser,Aslan, Ozlem Colak,Kocer, Ugur Korean Society of Plastic and Reconstructive Surge 2013 Archives of Plastic Surgery Vol.40 No.6

Background The most common cause of skin graft failure is the collection of blood or serous fluid underneath the graft. In our study, we describe the use of silicone tube for tie-over dressing to secure the skin graft margins with the aim of decreasing loss of the skin graft, particularly in grafting of deep wounds. Methods Between March 2008 and July 2011, we used this technique in 17 patients with skin defects with depths ranging from 3.5 to 8 mm (mean, 5.5 mm). First, the skin graft was sutured with 3/0 silk suture material from its corners. Then, a silicone round drain tube was sutured with 3/0 absorbable polyglactin 910 over the margins of the graft. Finally, long silk threads were tied over the bolus dressing, and the tie-over dressing was completed in the usual fashion. Results The mean follow-up was 7 months (range, 2-10 months) in the outpatient clinic. Graft loss on the graft margins due to hematoma or seroma was not developed. The results of adhesion between the graft and wound bed peripherally was excellent. Conclusions In our study, we suggest that use of a silicone tube for additional pressure on the edges of skin grafts in case of reconstruction of deep skin defects.

Differential gene expression analysis of human cumulus cells

Demiray, Sirin Bakti,Goker, Ege Nazan Tavmergen,Tavmergen, Erol,Yilmaz, Ozlem,Calimlioglu, Nilufer,Soykam, Huseyin Okan,Oktem, Gulperi,Sezerman, Ugur The Korean Society for Reproductive Medicine 2019 Clinical and Experimental Reproductive Medicine Vol.46 No.2

Objective: This study was performed to explore the possibility that each oocyte and its surrounding cumulus cells might have different genetic expression patterns that could affect human reproduction. Methods: Differential gene expression analysis was performed for 10 clusters of cumulus cells obtained from 10 cumulus-oocyte complexes from 10 patients. Same procedures related to oocyte maturation, microinjection, and microarray analyses were performed for each group of cumulus cells. Two differential gene expression analyses were performed: one for the outcome of clinical pregnancy and one for the outcome of live birth. Results: Significant genes resulting from these analyses were selected and the top 20 affected pathways in each group were analyzed. Circadian entrainment is determined to be the most affected pathway for clinical pregnancy, and proteoglycans in cancer pathway is the most affected pathway for live birth. Circadian entrainment is also amongst the 12 pathways that are found to be in top 20 affected pathways for both outcomes, and has both lowest p-value and highest number of times found count. Conclusion: Although further confirmatory studies are necessary, findings of this study suggest that these pathways, especially circadian entrainment in cumulus cells, may be essential for embryo development and pregnancy.