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S. D. Akbarov,M.A. Mehdiyev,M. Ozisik 국제구조공학회 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.67 No.2
This paper studies the non-axisymmetric 3D problem on the dynamics of the moving load acting in the interior of the hollow cylinder surrounded with elastic medium and this study is made by utilizing the exact equations of elastodynamics. It is assumed that in the interior of the cylinder the point located with respect to the cylinder axis moving forces act and the distribution of these forces is non-axisymmetric and is located within a certain central angle. The solution to the problem is based on employing the moving coordinate method, on the Fourier transform with respect to the spatial coordinate indicated by the distance of the point on the cylinder axis from the point at which the moving load acts, and on the Fourier series presentation of the Fourier transforms of the sought values. Numerical results on the critical moving velocity and on the distribution of the interface normal and shear stresses are presented and discussed. In particular, it is established that the non-axisymmetricity of the moving load can decrease significantly the values of the critical velocity.
Akbarov, S.D.,Mehdiyev, M.A.,Ozisik, M. Techno-Press 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.67 No.2
This paper studies the non-axisymmetric 3D problem on the dynamics of the moving load acting in the interior of the hollow cylinder surrounded with elastic medium and this study is made by utilizing the exact equations of elastodynamics. It is assumed that in the interior of the cylinder the point located with respect to the cylinder axis moving forces act and the distribution of these forces is non-axisymmetric and is located within a certain central angle. The solution to the problem is based on employing the moving coordinate method, on the Fourier transform with respect to the spatial coordinate indicated by the distance of the point on the cylinder axis from the point at which the moving load acts, and on the Fourier series presentation of the Fourier transforms of the sought values. Numerical results on the critical moving velocity and on the distribution of the interface normal and shear stresses are presented and discussed. In particular, it is established that the non-axisymmetricity of the moving load can decrease significantly the values of the critical velocity.
Metaplastic Breast Carcinoma: a Heterogeneous Disease
Gultekin, Melis,Eren, Gulnihan,Babacan, Taner,Yildiz, Ferah,Altundag, Kadri,Guler, Nilufer,Ozisik, Yavuz,Yazici, Gozde,Hurmuz, Pervin,Gurkaynak, Murat Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6
The aim of this study is to evaluate clinicopathologic characteristics and the multi-disciplinary treatment results of metaplastic breast cancer (MBC) patients treated in a single institute. Seventeen female patients with MBC treated in our department between June 2000 and January 2012 were identified and retrospectively evaluated. The median age at diagnosis was 46 years (range, 26-66 years). The median tumor size at diagnosis was 3.5 cm (range 1.5-12 cm). Six (35%) patients underwent breast conservation surgery and 11 (65%) mastectomy. Axillary lymph node metastasis was found in 6 (35%) patients. Twelve (71%) had triple negative tumors. Postoperative RT and systemic adjuvant treatment was given to all patients accordingly to stage and biological characteristics. Median follow-up time was 27 months (range, 12-151 months). At the time of this analysis, 14 (82%) patients were alive with no evidence of disease, and 1 (6%) was alive with disease. The 3-year OS was 91% and 5-year 80%, and DFS rates were 76% and 76%, respectively. Despite the young age of our patients with mostly high grade tumors, larger tumor size and higher rates of lymph node metastasis, the survival outcomes in our study are favorable in comparison with previously reported series.
Vardar-Yagli, Naciye,Sener, Gul,Saglam, Melda,Calik-Kutukcu, Ebru,Arikan, Hulya,Inal-Ince, Deniz,Savci, Sema,Altundag, Kadri,Kutluk, Tezer,Ozisik, Yavuz,Kaya, Ergun Baris Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2
Physical inactivity may an important outcome in the prognosis of breast cancer. Physical activity levels decrease significantly for breast cancer patients following the treatment and remain low after oncology treatment is completed. The aim of this study was to determine physical activity levels and to examine associations among physical activity, comorbidity, functional capacity, peripheral muscle strength, and psychosocial status in breast cancer patients. Forty breast cancer survivors were included in this study. Demographic and clinical characteristics were recorded. Physical activity was assessed with a short form of the International Physical Activity Questionnaire (IPAQ). We defined comorbid diseases according to the Charlson Comorbidity Index (CCI). Functional capacity was evaluated with a six-minute walk test (6MWT). Peripheral muscle strength was measured for quadriceps femoris muscle with a hand-held dynamometer. Psychosocial status was measured with the Hospital Anxiety Depression Scale (HADS). Forty percent of patients were inactive. The IPAQ total score was significantly related with quadriceps muscle strength (r=0.492; p<0.001) and HADS depression score (r=0.341; p<0.05). Marked correlations were also observed between IPAQ walking score and quadriceps muscle strength (r=0.449; p<0.001), HADS depression score (r=0.341; p<0.05), and CCI (r=-0.433; p<0.001). The CCI score was also markedly associated with quadriceps muscle strength (r=-0.413; p<0.001). 6MWT distance was not significantly correlated with any of the parameters. Regression analyses revealed that psychosocial status and peripheral muscle strength were significant predictors of physical activity estimated with the IPAQ short form and when combined, they explained 35% of the variance. Comorbidities, peripheral muscle strength and psychosocial status partially explain the variability of physical activity level in breast cancer survivors. These results suggest that physical inactivity contributes to worsening health in breast cancer survivors.