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        Full-Thickness Resection Device for Complex Colorectal Lesions in High-Risk Patients as a Last-Resort Endoscopic Treatment: Initial Clinical Experience and Review of the Current Literature

        Edris Wedi,Beatrice Orlandini,Mark Gromski,Carlo Felix Maria Jung,Irina Tchoumak,Stephanie Boucher,Volker Ellenrieder,Jurgen Hochberger 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.1

        The full-thickness resection device (FTRD) is a novel endoscopic device approved for the resection of colorectal lesions. This case-seriesdescribes the device and its use in high-risk patients with colorectal lesions and provides an overview of the potential indications inrecently published data. Between December 2014 and September 2015, 3 patients underwent endoscopic full thickness resection using the FTRD for colorectallesions: 1 case for a T1 adenocarcinoma in the region of a surgical anastomosis after recto-sigmoidectomy, 1 case for a non-liftingcolonic adenoma with low-grade dysplasia in an 89-year old patient and 1 for a recurrent adenoma with high-grade dysplasia in ayoung patient with ulcerative rectocolitis who was under immunosuppression after renal transplantation. Both technical and clinicalsuccess rates were achieved in all cases. The size of removed lesions ranged from 9 to 30 mm. Overall, the most frequent indication in the literature has been for lifting or non-lifting adenoma, submucosal tumors, neuroendocrintumors, incomplete endoscopic resection (R1) or T1 carcinoma. Colorectal FTRD is a feasible technique for the treatment of colorectal lesions and represents a minimally invasive alternative for eithersurgical or conventional endoscopic resection strategies.

      • PASTA ‘MADE IN TUSCANY’: TRACEABILITY AND SUSTAINABILITY AS MARKETING STRATEGY

        Ada Baldi,Marco Mancini,Anna Dalla Marta,Simone Orlandini 글로벌지식마케팅경영학회 2015 Global Fashion Management Conference Vol.2015 No.06

        This paper presents the case study of the Tuscan growers pasta, an example of linkage between people, territory, environment and food. The use of new technologies for agronomic management, cultivation protocols, and a food supply chain agreement guarantee high quality, traceability and sustainability from field to package, representing an innovative marketing strategy.

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        Effects of Mastitis on Buffalo Milk Quality

        Tripaldi, C.,Palocci, G.,Miarelli, M.,Catta, M.,Orlandini, S.,Amatiste, S.,Di Bernardini, R.,Catillo, G. Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.10

        The objectives of this study were to compare the effectiveness of different indicators of mammary inflammation in buffalo and to evaluate the association of the indicators with buffalo milk yield, composition, and rennet coagulation properties. This study was carried out at four buffalo farms in central Italy using a total of 50 lactating buffalo. Milk from each buffalo was tested at the beginning, middle, and end of lactation. To evaluate the relationship between mastitis markers and milk components, three classes were defined for each of the following markers: total somatic cell count (TSCC), differential somatic cell count (DSCC), and bacteriological results The regression coefficient for the reference method and the alternative method of determining TSCC was 0.81, indicating that the method routinely used to analyze buffalo milk consistently underestimated actual TSCC. The milk samples positive for udder-specific bacteria also had higher TSCC values than the samples that were negative for bacteria ($872{\times}10^3$/ml vs. $191{\times}10^3$/ml). In samples that were positive for udder-specific bacteria, polymorphonuclear leukocytes (PMN) made up greater than 50% of the cells. Moreover, only 1% of the samples in the lowest TSCC class were positive for bacteria. The correlation between TSCC and PMN was stronger (0.70), and PMN values in buffalo milk increased significantly when the TSCC class changed from low (38%) to medium and high (56% and 64%). Milk yield was negatively related to TSCC. Significant changes in lactose (4.87%, 4.80% and 4.64%) and chloride content (0.650 mg/ml, 0.862 mg/ml and 0.882 mg/ml) were also observed with increasing TSCC values. Higher TSCC was associated with impaired rennet coagulation properties: the clotting time increased, while the curd firming time ($p{\leq}0.05$) and firmness decreased. We concluded that in buffalo as in dairy cows, TSCC is a valid indicator of udder inflammation; we also confirmed that a value of $ 200{\times}10^3 cells/ml should be used as the threshold value for early identification of an animal affected by subclinical mastitis. In addition to its association with significantly decreased milk yield, a TSCC value above this threshold value was associated with changes in milk composition and coagulating properties.

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