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      • The Maori, Behavior, Modern Diets and Colorectal Cancers

        Caldararo, Niccolo Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

        Variation in diet and the rates of colorectal cancers have confounded researchers in recent years. Comparisons of populations in different geographic locations and of different ethnic origins have shown considerable differences in disease frequency, location and relation to diet. This paper revisits an earlier comparison of Maori rates of disease and diet based on data from 20 years ago with surprising changes in disease rates today.

      • Unsteady galloping of sharp-edged bluff bodies: experimental observations on the effect of the wind angle of attack

        Cong Chen,Bingyu Dai,Niccolo Wieczorek,Julian Unglaub,Klaus Thiele 한국풍공학회 2022 Wind and Structures, An International Journal (WAS Vol.35 No.4

        Light-weight or low-damped structures may encounter the unsteady galloping instability that occurs at low reduced wind speeds, where the classical quasi-steady assumption is invalid. Although this unsteady phenomenon has been widely studied for rectangular cross sections with one side perpendicular to the incidence flow, the effect of the mean wind angle of attack has not been paid enough attention yet. With four sectional models of different side ratios and geometric shapes, the presented research focuses on the effect of the wind angle of attack on unsteady galloping instability. In static tests, comparatively strong vortex shedding force was noticed in the middle of the range of flow incidence where the lift coefficient shows a negative slope. In aeroelastic tests with a low Scruton number, the typical unsteady galloping, which is due to an interaction with vortex-induced vibration and results in unrestricted oscillation initiating at the Kármán vortex resonance wind speed, was observed for the wind angles of attack that characterize relatively strong vortex shedding force. In contrast, for the wind angles of attack with relatively weak shedding force, an “atypical” unsteady galloping was found to occur at a reduced wind speed clearly higher than the Kármán-vortex resonance one. These observations are valid for all four wind tunnel models. One of the wind tunnel models (with a bridge deck cross section) was also tested in a turbulent flow with an intensity about 9%, showing only the atypical unsteady galloping. However, the wind angle of attack with the comparatively strong vortex shedding force remains the most unfavorable one with respect to the instability threshold in low Scruton number conditions.

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        Posterior Titanium Screw Fixation without Debridement of Infected Tissue for the Treatment of Thoracolumbar Spontaneous Pyogenic Spondylodiscitis

        Mauro Dobran,Maurizio Iacoangeli,Davide Nasi,Niccolo Nocchi,Alessandro Di Rienzo,Lucia di Somma,Roberto Colasanti,Carmela Vaira,Roberta Benigni,Valentina Liverotti,Massimo Scerrati 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.3

        Study Design: Retrospective study. Purpose: The aim of our study was to analyze the safety and effectiveness of posterior pedicle screw fixation for treatment of pyogenic spondylodiscitis (PSD) without formal debridement of the infected tissue. Overview of Literature: Posterior titanium screw fixation without formal debridement of the infected tissue and anterior column reconstruction for the treatment of PSD is still controversial. Methods: From March 2008 to June 2013, 18 patients with PSD underwent posterior titanium fixation with or without decompression, according to their neurological deficit. Postero-lateral fusion with allograft transplantation alone or bone graft with both the allogenic bone and the autologous bone was also performed. The outcome was assessed using the visual analogue scale (VAS) for pain and the Frankel grading system for neurological status. Normalization both of C-reactive protein (CRP) and erythrocyte sedimentation rate was adopted as criterion for discontinuation of antibiotic therapy and infection healing. Segmental instability and fusion were also analyzed. Results: At the mean follow-up time of 30.16 months (range, 24–53 months), resolution of spinal infection was achieved in all patients. The mean CRP before surgery was 14.32±7.9 mg/dL, and at the final follow-up, the mean CRP decreased to 0.5±0.33 mg/ dL (p <0.005). Follow-up computed tomography scan at 12 months after surgery revealed solid fusion in all patients. The VAS before surgery was 9.16±1.29 and at the final follow-up, it improved to 1.38±2.03, which was statistically significant (p <0.05). Eleven patients out of eighteen (61.11%) with initial neurological impairment had an average improvement of 1.27 grades at the final follow-up documented with the Frankel grading system. Conclusions: Posterior screw fixation with titanium instrumentation was safe and effective in terms of stability and restoration of neurological impairment. Fixation also rapidly reduced back pain.

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