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RISS 인기검색어
- 검색키워드
- 저자 : Nevena Kardum (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Effects of Polyphenol-Rich Chokeberry Juice on Antioxidant/Pro-Oxidant Status in Healthy Subjects
Nevena Kardum,Aleksandra Konic´-Ristic,Katarina Savikin,Slavica Spasic,Aleksandra Stefanovic,Jasmina Ivanisevic,Milica Miljkovic 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.8
Berry fruits are a rich source of polyphenols, especially anthocyanins: well-known potent anti-oxidant phytochemicals. The purpose of this study was to evaluate beneficial effects of long-term consumption of polyphenol-rich organic chokeberry juice on different markers of antioxidant/pro-oxidant status in healthy female volunteers. Twenty-nine women, aged 25–49, were included in the study. Serological markers of oxidative stress and antioxidant defence, blood pressure, routine biochemical, and anthropometric parameters were analyzed at baseline and after twelve weeks of regular chokeberry juice consumption. Significant decrease in thiobarbituric acid-reactive substances level (TBARS; P < .001) and pro-oxidantantioxidant balance (PAB; P < .05), as well as increase in paroxonase-1 activity toward diazoxon (P < .01) were found. Total oxidative status and sulphydryl groups levels were not significantly influenced by the intervention. Anthropometric, biochemical parameters, and blood pressure values were within the referent values for all subjects and were not influenced by the chokeberry juice consumption. However, we found positive correlation between age, body mass index, waist circumference, body fat percent, blood pressure, and analyzed marker of lipid peroxidation, which was influenced by the consumption. In conclusion, the fine modulation of several antioxidant/pro-oxidant status biomarkers observed in healthy subjects indicates putative prophylactic effects of polyphenol-rich chokeberry juice and supports its importance as part of an optimal diet.
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Nevena Kardum,Branislav Milovanovic,Katarina Savikin,Gordana Zdunic,Slavica Mutavdzin,Tatjana Gligorijevic,Slavica Spasic 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.11
Epidemiological studies have shown a positive association between intake of foods rich in antioxidants and lower incidence of cardiovascular disease development. Polyphenols are considered the most abundant and important dietaryantioxidants. The aim of this study was to evaluate effects of polyphenol-rich chokeberry juice consumption on 24-h ambulatory monitored blood pressure (BP) level in subjects with no pharmacologically treated high normal BP or grade I hypertension. Twenty-three subjects (12 men and 11 women) aged 33–67 were enrolled and instructed to consume 200mL of juice daily for 4 weeks. Participants were divided in two groups, based on prevalence of sympathetic or parasympatheticactivity. Measurements of biochemical parameters and heart rate variability analysis were also applied. At the end of the intervention period, average 24-h and awake systolic and diastolic BP were significantly decreased (P < .05). This was more pronounced in the group with prevalence of sympathetic activity. Significant reduction in triglyceride level (P < .05) and a reducing effect on total and low-density lipoprotein cholesterol were also found. Obtained results indicate a positive impact of regular chokeberry juice consumption on BP and lipid status in pharmacologically untreated hypertensive subjects.
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Dietary Supplementation with Polyphenol-Rich Chokeberry Juice Improves Skin Morphology in Cellulite
Katarina Šavikin,Nemanja Menković,Gordana Zdunić,Dejan Pljevljakušić,Slavica Spasić,Nevena Kardum,Aleksandra Konić-Ristić 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.5
The aim of our study was to investigate possible beneficial effects of organic chokeberry juice (OCJ) consumption in the treatment of cellulite. Twenty-nine women aged 25–48 with a cellulite grade 2 according to the Nurnberger–Muller scale were included. Anthropometric and biochemical parameters were measured. Skin structure was analyzed by ultrasonography. All subjects consumed 100mL of OCJ per day, during 90 days. Measurements of investigated parameters were performed at 0, 45, and 90 days of the study. A marked reduction in the subcutaneous tissue thickness was observed in all subjects, with the average reduction of 1.9 mm. The length of subcutaneous tissue fascicles (ScTFL) was reduced in 97% (28 out of 29) of subjects, with the average value of 1.18 mm. After 45 days of chokeberry juice consumption, reduction of edema was observed in 55.2% of the subjects with edema at the baseline, while at the endpoint of the study, edemas were not observed in any of the subjects involved in the study. OCJ could have beneficial effects on the cellulite condition, including the length of ScTFL, subcutaneous tissue, and dermis thickness as well as on edema reduction.
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