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RISS 인기검색어
- 검색키워드
- 저자 : Nazim Hussain (검색결과 2 건)
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Salma Chaush,Nazim Husain,Mohd Khalid,Meenu Doni,Mohd Qudrathullah Khan,Md Majid Hussain 경희대학교 융합한의과학연구소 2023 Oriental Pharmacy and Experimental Medicine Vol.23 No.2
Hemorrhoidal disease is one of the most common gastrointestinal ailments affecting life quality of the patients. Unani classical literature is replete with anti-hemorrhoidal drugs, but scientific evidence is lacking. Therefore, Safūf Zāj (powdered alum) and Marham-e-Māzū (gall ointment) having potent anti-hemorrhoidal actions were selected to evaluate their efficacy in hemorrhoids. This clinical trial was conducted on 30 participants with hemorrhoids, aged > 18 years. All the participants received Safūf Zāj for sitz baths and Marham-e-Māzū to be applied twice daily for 2 weeks. Primary outcome measures were: change in pain intensity, anal itching, and defecate discomfort assessed on 100 mm VAS scale and per-rectal bleeding assessed on 4-point scale. Secondary outcome measures were: change in the size of the external hemorrhoidal mass assessed on 5-point scale, grade of internal hemorrhoid assessed by Goligher classification and quality of life (QoL) assessed on SF-12 questionnaire. The per-protocol analysis was done on 30 participants and statistically significant improvement was seen in primary and secondary outcome measures. Moreover, both the mental and psychological components of QoL were improved. The study inferred that therapeutic approach of Safūf Zāj and Marham-e-Mazu is safe and efficacious in hemorrhoids. Future studies with well-designed RCTs are highly recommended.
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Antony Maodzeka,Qian Wang,Xiaoyang Chen,Nazim Hussain,Dezhi Wu,Lixi Jiang 한국식물학회 2019 Journal of Plant Biology Vol.62 No.3
Application of 5-Aminolevulinic acid (ALA) toplants not only affects their growth, but also influences thenutritional values of plant organs. Oilseed rape (Brassicanapus L.) is an important source of vegetable oil and variouscompounds benefiting human health. However, limitedinformation is available regarding the effect of ALA on thegrowth of this important crop. Here, we investigated theconsequence of ALA application on oilseed rape seedlings. We found that moderate ALA concentrations (0.5 or 1 mg/L)caused an increase in the dry weight of the seedling biomassand the contents of various bioactive compounds, i.e. solublesugar, phenolic compounds, ascorbate, and glucosinolatesetc, and the upregulated expressional levels of the genesencoding RuBisCO, namely, BnRBCL and BnRBCS, andother genes such as BnUGT79B1, BnMYB12 and MYB28that regulate the synthesis of phenolic compounds andglucosinolates respectively. On the other hand, high ALAconcentrations (5 and 10 mg/L) gave rise to oxidative stressthat negatively affected oilseed rape growth, and causeddeleterious effects by reducing various bioactive compounds,but increasing tocopherols that may serve as a stress mitigatoryagent. With the high ALA concentrations, the ultrastructureof chloroplasts was notably damaged, featured with largestarch grains and fewer plastoglobules.
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