http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Natarajan Sudhakar (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Natarajan Sudhakar,Thangarajan Rajkumar,Kamalalayam Raghavan Rajalekshmy,Nirmala Karunakaran Nancy 대한혈액학회 2017 Blood Research Vol.52 No.1
Background: This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identi-fied age-related predominance in VDJ rearrangements. Methods: IGH rearrangements were studied in 50 precursor B-ALL cases (common ALL=37, pre-B ALL=10, pro-B ALL=3) by polymerase chain reaction (PCR) heteroduplex analysis. Twenty randomly selected clonal IGH rearrangement sequences were analyzed using the IMGT/V-QUEST tool. Results: Clonal IGH rearrangements were detected in 41 (82%) precursor B-ALL cases. Among the IGHV1-IGHV7 subgroups, IGHV3 was used in 25 (50%) cases. Among the IGHD1-IGHD7 genes, IGHD2 and IGHD3 were used in 8 (40%) and 5 (25%) clones, respectively. Among the IGHJ1-IGHJ6 genes, IGHJ6 and IGHJ4 were used in 9 (45%) and 6 (30%) clones, respectively. In 6 out of 20 (30%) IGH rearranged sequences, CDR3 was in frame whereas 14 (70%) had rearranged sequences and CDR3 was out of frame. A so-matic mutation in Vmut/Dmut/Jmut was detected in 14 of 20 IGH sequences. On average, Vmut/Dmut/Jmut were detected in 0.1 nt, 1.1 nt, and 0.2 nt, respectively. Conclusion: The IGHV3 gene was frequently used whereas lower frequencies of IGHV5 and IGHV6 and a higher frequency of IGHV4 were detected in children compared with young adults. The IGHD2 and IGHD3 genes were over-represented, and the IGHJ6 gene was predom-inantly used in precursor-B-ALL. However, the IGH gene rearrangements in pre-cursor-B-ALL did not show any significant age-associated genotype pattern attributed to our population.
-
Natarajan Sudhakar,Thangarajan Rajkumar,Kamalalayam Raghavan Rajalekshmy,Nirmala Karunakaran Nancy 대한혈액학회 2017 Blood Research Vol.52 No.1
Background: This study characterized clonal IG heavy V-D-J (IGH) gene rearrangements in South Indian patients with precursor B-cell acute lymphoblastic leukemia (precursor B-ALL) and identi-fied age-related predominance in VDJ rearrangements. Methods: IGH rearrangements were studied in 50 precursor B-ALL cases (common ALL=37, pre-B ALL=10, pro-B ALL=3) by polymerase chain reaction (PCR) heteroduplex analysis. Twenty randomly selected clonal IGH rearrangement sequences were analyzed using the IMGT/V-QUEST tool. Results: Clonal IGH rearrangements were detected in 41 (82%) precursor B-ALL cases. Among the IGHV1-IGHV7 subgroups, IGHV3 was used in 25 (50%) cases. Among the IGHD1-IGHD7 genes, IGHD2 and IGHD3 were used in 8 (40%) and 5 (25%) clones, respectively. Among the IGHJ1-IGHJ6 genes, IGHJ6 and IGHJ4 were used in 9 (45%) and 6 (30%) clones, respectively. In 6 out of 20 (30%) IGH rearranged sequences, CDR3 was in frame whereas 14 (70%) had rearranged sequences and CDR3 was out of frame. A so-matic mutation in Vmut/Dmut/Jmut was detected in 14 of 20 IGH sequences. On average, Vmut/Dmut/Jmut were detected in 0.1 nt, 1.1 nt, and 0.2 nt, respectively. Conclusion: The IGHV3 gene was frequently used whereas lower frequencies of IGHV5 and IGHV6 and a higher frequency of IGHV4 were detected in children compared with young adults. The IGHD2 and IGHD3 genes were over-represented, and the IGHJ6 gene was predom-inantly used in precursor-B-ALL. However, the IGH gene rearrangements in pre-cursor-B-ALL did not show any significant age-associated genotype pattern attributed to our population.
-
Kalaiarasu Srinivasan,Natarajan Sudhakar 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.3
Due to the fast-switching process in DC-DC converters, electromagnetic interference (EMI) is created and affects the performance of the converters used in electric vehicles (EV) and leads to malfunctions of nearby weak components. Hence, EMI should be mitigated in the fast-switching process of DC-DC converters for their better performance. Recently, a randomized carrier frequency modulation with a fixed duty cycle (RCFMFD) based digital chaotic pulse width modulation (DCPWM) has been used in the EMI mitigation process, and also it gives better results than the periodic PWM technique. For most of the PV panel and super-capacitor bank-based power systems, a two-stage cascaded boost (TSCB) DC-DC converter have been used for voltage lifting techniques. In this work, FPGA controller-based DCPWM and periodic PWM techniques has been implemented on a 40W, 200kHz (TSCB) DC-DC converter to test and suppress the conducted EMI. During periodic PWM approach −58dBV of conducted EMI was generated in this converter and it has been reduced to −68dBV in chaotic approach. Totally −10dBV which is equal to 3V(RMS) of conducted EMI has been mitigated in DCPWM compared with periodic PWM on two-stage cascaded boost converter for EV applications.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
