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To Use Facebook for Good: Usage, Cyberbullying Involvement, and Perceived Social Support
Natalie Wong,Catherine Mcbride 한국아동학회 2016 Child studies in Asia-Pacific context Vol.6 No.2
We examined the relationship between the extent of Facebook usage and social wellbeing with consideration of cyberbullying involvement using a person-oriented approach. Survey data were collected from a sample of 312 secondary students from Grades 7 and 8 in Hong Kong. Levels of cyberbullying involvement, Facebook usage and perceived social support were investigated. Participants were classified into three clusters based on the different levels of Facebook usage and cyberbullying victimization through cluster analyses (i.e., frequent Facebook user/noncyberbullied victim, frequent Facebook user/cyberbullied victim, and uninvolved). Our results showed that frequent Facebook users who are cyberbullied tend to engage in cyberbullying perpetration significantly more than the frequent Facebook users who are not cyberbullied, even when the latter reported higher Facebook usage. This result provides some support for the idea that cyberbullying victimization has additional value on top of the level of usage in explaining one’s participation in cyberbullying perpetration. As expected, frequent Facebook users who were not cyberbullied reported the highest perceived social support among the three groups. What is even more interesting is the equal level of perceived social support found between the cyberbullied victims and the uninvolved. Our results suggest that, although limiting adolescents’ Internet use might reduce their risks of being involved in cyberbullying, it might also take away the potential benefits they could get from interacting with the online community. Benefits of using the person-oriented approach in the study of cyberbullying are discussed.
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To Use Facebook for Good: Usage, Cyberbullying Involvement, and Perceived Social Support
Wong, Natalie,McBride, Catherine Korean Association of Child Studies 2016 Child studies in Asia-Pacific context Vol.4 No.1
We examined the relationship between the extent of Facebook usage and social well-being with consideration of cyberbullying involvement using a person-oriented approach. Survey data were collected from a sample of 312 secondary students from Grades 7 and 8 in Hong Kong. Levels of cyberbullying involvement, Facebook usage and perceived social support were investigated. Participants were classified into three clusters based on the different levels of Facebook usage and cyberbullying victimization through cluster analyses (i.e., frequent Facebook user/noncyberbullied victim, frequent Facebook user/cyberbullied victim, and uninvolved). Our results showed that frequent Facebook users who are cyberbullied tend to engage in cyberbullying perpetration significantly more than the frequent Facebook users who are not cyberbullied, even when the latter reported higher Facebook usage. This result provides some support for the idea that cyberbullying victimization has additional value on top of the level of usage in explaining one's participation in cyberbullying perpetration. As expected, frequent Facebook users who were not cyberbullied reported the highest perceived social support among the three groups. What is even more interesting is the equal level of perceived social support found between the cyberbullied victims and the uninvolved. Our results suggest that, although limiting adolescents' Internet use might reduce their risks of being involved in cyberbullying, it might also take away the potential benefits they could get from interacting with the online community. Benefits of using the person-oriented approach in the study of cyberbullying are discussed.
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Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine
( Stephen T. Deyrup ),( Natalie C. Stagnitti ),( Mackenzie J. Perpetua ),( Siu Wah Wong-deyrup ) 한국응용약물학회 2021 Biomolecules & Therapeutics(구 응용약물학회지) Vol.29 No.2
Traditional Chinese medicine (TCM) was the primary source of medical treatment for the people inhabiting East Asia for thousands of years. These ancient practices have incorporated a wide variety of materia medica including plants, animals and minerals. As modern sciences, including natural products chemistry, emerged, there became increasing efforts to explore the chemistry of this materia medica to find molecules responsible for their traditional use. Insects, including beetles have played an important role in TCM. In our survey of texts and review articles on TCM materia medica, we found 48 species of beetles from 34 genera in 14 different families that are used in TCM. This review covers the chemistry known from the beetles used in TCM, or in cases where a species used in these practices has not been chemically studied, we discuss the chemistry of closely related beetles. We also found several documented uses of beetles in Traditional Korean Medicine (TKM), and included them where appropriate. There are 129 chemical constituents of beetles discussed.
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( Won Young Tak ),( Vincent Wai-sun Wong ),( George Boon Bee Goh ),( Pin-nan Cheng ),( Eric J. Lawitz ),( Zobair M. Younossi ),( Raj Vuppalanchi ),( Natalie H. Bzowej ),( Ziad Younes ),( Naim Alkhouri 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Background: Routinely available noninvasive tests of fibrosis (NITs) can be used to identify patients with advanced fibrosis due to NASH, but their performance may vary by race. Our aim was to evaluate the effect of patient race on the diagnostic performance of NITs using data from the global phase 3 STELLAR studies of selonsertib. Methods: The STELLAR studies (NCT03053050 and NCT03053063) enrolled patients with bridging fibrosis (F3) or compensated cirrhosis (F4) due to NASH (NAFLD Activity Score [NAS] ≥3). Baseline liver biopsies were centrally read using the NASH Clinical Research Network classification and NITs, including the NAFLD fibrosis score (NFS), Fibrosis-4 (FIB-4) index, Enhanced Liver Fibrosis (ELF) test, and liver stiffness by transient elastography (LS by TE) were measured. The performance of these tests to discriminate advanced (F3-F4) fibrosis by self-reported patient race was evaluated using areas under the receiver operating characteristics curves (AUROCs) with 5-fold cross-validation repeated 100x. Results for White and Asian patients are presented; data for other races (5% of patients screened) are excluded. Results: Among 3202 patients screened for the STELLAR studies with evaluable liver histology, 24% were Asian and 71% were White. The median age was 58 years in both groups; 47% of Asians and 57% of Whites were female (p<0.0001). The prevalence of F3-F4 fibrosis was 67% in Asians and 72% in Whites (p=0.01). AUROCs for each of the NITS for the discrimination of advanced fibrosis were similar between Asian and White patients (Table). In general, literature-based thresholds for the NITs had similar sensitivity and specificity among the specific racial subgroups. Conclusion: In these large, global phase 3 trials, the diagnostic performance of routinely available NITs for the discrimination of advanced fibrosis due to NASH was acceptable and similar between Asian and White patients.
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