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문헌 초역 : 폐결핵 환자의 기관내 채담에 의한 결핵균의 검색, "트레핀"에 의한 경피폐생검
( Kohei Hara ),( Toshiro Oda ),( Masao Nakatomi ),( Nobuhiro Horiuchi ),( Tuneo Tsutsumi ),( Masaki Hirota ),( Nobuoki Mori ),( Masaru Nasu ),( Atsushi Seito ),( Hisashi Ishikawa ),( E. Garner King ) 대한결핵 및 호흡기학회 1977 Tuberculosis and Respiratory Diseases Vol.24 No.1
Transoral Robotic-Assisted Neurosurgery for Skull Base and Upper Spine Lesions
Jun Muto,Ichiro Tateya,Hirofumi Nakatomi,Ichiro Uyama,Yuichi Hirose 대한척추신경외과학회 2024 Neurospine Vol.21 No.1
Objective: The application of the da Vinci Surgical System in neurosurgery is limited due to technical difficulties requiring precise maneuvers and small instruments. This study details the advantages and disadvantages of robotics in neurosurgery and the reachable range of the transoral approach to lesions of the skull base and upper cervical spine. Methods: In a cadaver study, the da Vinci Xi robot, lacking haptic feedback, was utilized for sagittal and coronal approaches on 5 heads, facilitating dura suturing in 3, with a 30°-angled drill for bone removal. Results: Perfect exposure of all the nasopharyngeal sites, clivus, sellar, and choana, including the bilateral eustachian tubes, was achieved without any external incisions using this palatal split approach of transoral robotic surgery. The time required to perform a single stitch, knot, and complete single suture in robotic suturing of deep-seated were significantly less compared to manual suturing via the endonasal approach. Conclusion: This is the first report to show the feasibility of suturing the dural defect in deepseated lesions transorally and revealed that the limit of reach in the coronal plane via a transoral approach with incision of the soft palate is the foramen ovale. This preclinical investigation also showed that the transoral robotic approach is feasible for lesions extending from the sellar to the C2 in the sagittal plane. Refinement of robotic instruments for specific anatomic sites and future neurosurgical studies are needed to further demonstrate the feasibility and effectiveness of this system in treating benign and malignant skull base lesions.
Uchino, Junji,Hirano, Ryosuke,Tashiro, Naoki,Yoshida, Yuji,Ushijima, Shinichiro,Matsumoto, Takemasa,Ohta, Keiichi,Nakatomi, Keita,Takayama, Koichi,Fujita, Masaki,Nakanishi, Yoichi,Watanabe, Kentaro Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Aims and Background: To evaluate the efficacy of a combination of aprepitant and conventional antiemetic therapy in patients with advanced or recurrent lung cancer receiving moderately emetogenic chemotherapy (MEC). Methods: Patients with advanced or recurrent lung cancer who were treated with MEC regimens at the Department of Respiratory Medicine, Fukuoka University Hospital, were included and classified into the following groups: control group (treatment: 5-HT3 receptor antagonists + dexamethasone) and aprepitant group (treatment: 5-HT3 receptor antagonists + dexamethasone + aprepitant). The presence or absence of chemotherapy-induced nausea and vomiting (CINV) was evaluated according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0; patients with grade 1 or above were considered positive for CINV. Food intake per day, completion of planned chemotherapy, and progression-free survival (PFS) achieved by chemotherapy were investigated. Results: The complete suppression rate of nausea in the aprepitant group was significantly higher than that in the control group (p = 0.0043). Throughout the study, the food intake in the aprepitant group was greater than that in the control group, with the rate being significantly higher, in particular, on day 5 (p = 0.003). The completion rate of planned chemotherapy was also higher in the aprepitant group (p = 0.042). PFS did not differ significantly, but tended to be improved in the aprepitant group. Conclusions: The aprepitant group showed significantly higher complete suppression of nausea, food intake on day 5, and completion of planned chemotherapy than the control group.