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RISS 인기검색어
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- 저자 : Mustafa Taş (검색결과 4 건)
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Selim Taşci,Reşat Can Özden,Mustafa Anik 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.2
Electroless Ni–P–W was coated on AZ91 sheets with various W contents and both the corrosion and wear resistance characteristicsof these coatings were observed. The increase in W content resulted in a decrease in P content and an increase inthe crystallinity of the electroless coatings. The corrosion resistance of the electroless coatings increased upon increase inW content of the electroless coatings up to approximately 5%. Above this content, however, the corrosion resistance tendedto decrease due to the disturbed grain structure of the electroless coating. But both the surface hardness and wear resistanceincreased concurrently due to the positive contribution of W solid solution hardening. The applied heat treatment resulted ina decrease in the corrosion resistance due to the disappearance of the amorphous structure and increase in both the surfacehardness and wear resistance due to the precipitation hardening. Al2O3dispersion was better with the nonionic surfactant,as compared to the anionic and cationic surfactants. Composite coating reduced the corrosion resistance and increased thewear resistance of the electroless Ni–P–W coatings. The applied heat treatment was observed to have positive contributionto Ni–P–W coatings in getting the optimum corrosion and wear resistance combination.
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Erinç Uludamar,Mustafa Taş,Sami Gökberk Biçer,Cihan Yıldırım,Ebru Aykut Yıldırım,Kerimcan Çelebi 한국자동차공학회 2020 International journal of automotive technology Vol.21 No.2
The connection surfaces of drag-link must be tough and safe enough to carry transmitted forces that exert on the product in service conditions. Therefore, undulated forming takes place in machining process to stay the rod-ends in the rod. In the rod-end, after forming process, a straight part which remains on the body causes extra cost and weight on the product. In this study, the result of shortening of rod-end which was produced from C45+N quality steel was investigated by comparing with the unmodified rod-end. The comparison was carried out by fatigue test and Finite Element Analysis. The results showed that the cropped part has almost no effect on the durability of the product. It is measured that the modification result with 0,082 kg weight reduction on each rod-end and 5 seconds shortening of machining process were observed by the modification on rod-end. The effect of modification on the part was examined in a case study. The case study indicated that annual expenses of raw material lowered by $9.124,56 and total cost decreased by $11.480,20.
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Ozan Ertekin,Meltem Kutnu,Aslı Aras Taşkın,Mustafa Demir,Ayten Yazgan Karataş,Gülay Özcengiz 한국미생물학회 2020 The journal of microbiology Vol.58 No.4
Bacilysin, as the simplest peptide antibiotic made up of only L-alanine and L-anticapsin, is produced and excreted by Bacillus subtilis under the control of quorum sensing. We analyzed bacilysin-nonproducing strain OGU1 which was obtained by bacA-targeted pMutin T3 insertion into the parental strain genome resulting in a genomic organization (bacA ::lacZ::erm::bacABCDEF) to form an IPTG-inducible bac operon. Although IPTG induction provided 3- to 5-fold increment in the transcription of bac operon genes, no bacilysin activity was detectable in bioassays and inability of the OGU1 to form bacilysin was confirmed by UPLC-mass spectrometry analysis. Phenotypic analyses revealed the deficiencies in OGU1 with respect to colony pigmentation, spore coat proteins, spore resistance and germination, which could be rescued by external addition of bacilysin concentrate into its cultures. 2DE MALDI-TOF/MS and nanoLC-MS/MS were used as complementary approaches to compare cytosolic proteomes of OGU1. 2-DE identified 159 differentially expressed proteins corresponding to 121 distinct ORFs. In nanoLCMS/ MS, 76 proteins were differentially expressed in OGU1. Quantitative transcript analyses of selected genes validated the proteomic findings. Overall, the results pointed to the impact of bacilysin on expression of certain proteins of sporulation and morphogenesis; the members of mother cell compartment- specific σE and σK regulons in particular, quorum sensing and two component-global regulatory systems, peptide transport, stress response as well as CodY- and ScoCregulated proteins.
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Investigation of Dysregulation of Several MicroRNAs in Peripheral Blood of Schizophrenia Patients
Mehmet Akif Camkurt,Fatih Karababa,Mehmet Emin Erdal,Hüseyin Bayazıt,Sultan Basmacı Kandemir,Mustafa Ertan Ay,Hasan Kandemir,Özlem İzci Ay,Erdinç Çiçek,Salih Selek,Bahar Taşdelen 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.3
Objective: The prevalence of schizophrenia is 1%, and it is a debilitating disorder that often results in a shortened lifespan. Peripheral blood samples are good candidates to investigate because they can be easily drawn, and they are widely studied in psychiatric disorders. MicroRNAs are small non-coding RNA transcripts. They regulate the expression of genes by binding to the 3’-untranslated region (UTR) of mRNAs and pointing them to degrade. In this study, we aimed to investigate the expression of miR-9-5p, miR-29a-3p, miR-106-5p, miR-106b-5p, miR-107, miR-125a-3p, and miR-125b-3p in schizophrenia patients and healthy controls. Methods: We collected blood samples from 16 patients with schizophrenia and 16 healthy controls. MicroRNAs were measured with reverse transcriptase polymerase chain reaction. Results: Schizophrenia patients showed statistically significant upregulation of five microRNAs: miR9-5p (p=0.002), miR29a-3p (p<0.001), miR106b-5p (p=0.002), miR125a-3p (p<0.001), and miR125b-3p (p=0.018). Conclusion: Our results increased the value of the miR106 and miR29 families as potentially and consistently dysregulated in psychiatric disorders. Our results should be considered preliminary, and they need confirmation in future studies with larger sample sizes.
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