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Acquired noncaustic esophageal strictures in children
Sag, Elif,Bahadir, Aysenur,Imamoglu, Mustafa,Sag, Sefa,Reis, Gokce Pinar,Erduran, Erol,Cakir, Murat The Korean Pediatric Society 2020 Clinical and Experimental Pediatrics (CEP) Vol.63 No.11
Background: Esophageal stricture (ES) is an uncommon clinic entity in pediatrics that may be congenital or acquired in childhood. Acquired noncaustic ES is very rare, and clinical features of affected patients are unknown. Purpose: We aimed to evaluate the clinical findings, and outcomes of patients with acquired noncaustic ES to aid physicians in the early referral of patients to gastroenterologists. Methods: The medical data of patients with acquired noncaustic ES who were followed in our gastroenterology clinic between January 2009 and December 2019 were reviewed. Results: Acquired noncaustic ES was found in 12 of the 4,950 patients (0.24%) who underwent endoscopy during the study period. The main symptoms were dysphagia (58.3%), vomiting (33.3%), and chronic anemia (8.3%). Chronic malnutrition and underweight were found in 66.6% of the patients. The most common etiological factors were radiotherapy, peptic reflux, and achalasia (16.6%, each), while chemotherapy, squamous-cell carcinoma (SC) of the esophagus, eosinophilic esophagitis (EoE), esophageal web, epidermolysis bullosa, and esophageal diverticulum (8.2%, each) were the other etiological factors. Patients with EoE underwent endoscopic bougie dilation in addition to steroid use and elimination diet. Patients with epidermolysis bullosa and esophageal web underwent bougie dilation. Patients with peptic reflux-related ES were initially put on antireflux therapy, but during follow-up, one patient required esophageal replacement with colonic interposition. Patients with radiotherapy-related ES recovered with medical therapy. The patient with initially underwent surgical gastrostomy and tumoral mass excision. The patient then received chemotherapy and radiotherapy and underwent jejunal interposition. Patients with achalasia underwent surgical esophagomyotomy. Conclusion: The presence of solid dysphagia, malnutrition, and an associated disease may alert physicians to the presence of ES.
Esra Durduran,Huseyin Altundag,Mustafa Imamoglu,Salih Zeki Yıldız,Mustafa Tuzen 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.27 No.-
Silica gel was functionalized with N-(2-aminoethyl)-2,3-dihydroxybenzaldimine group (AEDHB-SG) andcharacterized by elemental analysis and FT-IR spectroscopy. Preconcentration conditions of Cd(II), Cu(II),Ni(II) and Pb(II) were investigated on the AEDHB-SG loaded column using a solid phase extractiontechnique. The effects of parameters such as the pH, sample volume, flow rates, matrix ions wereexamined. Adsorption capacity of AEDHB-SG for Cd(II), Cu(II), Ni(II) and Pb(II) was 0.40, 0.56, 0.50 and0.23 mmol g 1. The accuracy of the developed method was confirmed by certified reference materials. Optimized method was applied to water and food samples for the determination of trace metals usingICP-OES.
Accessory Hepatic Lobe: A Rare Cause of Prehepatic Portal Hypertension in a Child
Sag, Elif,Cansu, Aysegul,Imamoglu, Mustafa,Cakir, Murat The Korean Society of Pediatric Gastroenterology 2018 Pediatric gastroenterology, hepatology & nutrition Vol.21 No.4
Accessory hepatic lobe is noted as and considered a rare disease in children. It can manifest with various symptoms and complications depending on the location, volume, type and position of the disease as presented on a child. The patient presented as a 14-month-old girl who was seen with a notable hepatosplenomegaly and portal hypertension. A diagnosis was made after taking an extensive medical history, observation and radiological examinations. The formal diagnosis was a prehepatic portal hypertension associated with accessory hepatic lobe.
Morphine: Patient Knowledge and Attitudes in the Central Anatolia Part of Turkey
Colak, Dilsen,Oguz, Arzu,Yazilitas, Dogan,Imamoglu, Inanc Goksen,Altinbas, Mustafa Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12
Background: In Muslim majority countries (MMC) opioid use for pain management is extremely low. The underlying factors contributing to this are not well defined. Aim: The aim of this study was to survey the attitudes of cancer patients towards morphine use for pain management in a MMC and identify the factors that influence patient decisions to accept or refuse morphine as treatment for cancer pain. Settings/participants: Patients were questioned whether they had pain or not, the severity and the medications for pain management. Questions included what type of medication they thought morphine was, whether or not they would be willing to take morphine if recommended for pain management and the basis for their decision if they were against morphine use. Results: Four hundred and eighty-eight patients participated in the study. Some 50% of the patients who refused morphine use and 36.8% of the patients who would prefer another drug, if possible, identified fear of addiction as the basis for their decision. Reservation of morphine for later in their disease was the case for 22.4% of the patients who refused morphine use. Only 13.7 % of the patients refusing morphine and 9.7% of the patients who preferred another drug, if possible, cited religious reasons as the basis for this decision. Conclusions: Identifying the underlying factors contributing to low opioid use for pain management in MMC is important. Once the underlying factors were identified, all efforts should be taken to overcome them as they are barriers to improving patient pain management.