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RISS 인기검색어
- 검색키워드
- 저자 : Muhammad Nauman Sarwar (검색결과 2 건)
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Muhammad Nauman Sarwar,Ick Soo Kim 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
Diclofenac sodium (DLF) salt loaded polyacrylonitrile (PAN) nanofibers were successfully prepared by electrospinning. The inclusion of DLF in PAN nanofibers increased the nanofiber diameter from ~200 nm to ~500 nm, proportional to the amount of DLF loaded into it. FTIR spectra confirm the entrapment of the DLF into the PAN nanofibers. X-ray diffraction pattern showed that PAN nanofibers had caused the misalignment in the polymeric chains of the PAN, thus resulting in a decrease of the peak intensity at 2θ = 17°. The DLF loaded PAN nanofibers were efficient against the gram-positive Staphylococcus aureus and gram-negative Escherichia coli. DLF loaded PAN nanofiber showed good cell viability ~95% for L929 cells in more extended incubation periods. The release profile indicates that the DLF release from the PAN nanofibers was slow and is beneficial as PAN nanofiber will retain the bioactive agent throughout their useful life. Cell adhesion micrographs show that cell-cell interaction is stronger than the cell-material interaction. This type of weak cell interaction with the wound dressing is particularly advantageous, as this will not disturb the wound surface during the nursing of the wound.
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Nadir Hussain,Sana Ullah,Muhammad Nauman Sarwar,Motahira Hashmi,Muzamil Khatri,Takumi Yamaguchi,Zeeshan Khatri,김익수 한국섬유공학회 2020 Fibers and polymers Vol.21 No.12
Antibacterial products have paid much more attraction all over global world. In this study, a novel and economicalrout has been studied for antibacterial product, ultrafine nylon-6 (NY-6 NFS) nanofibers impregnated into garlic sour wassynthesized by electrospinning method. The morphology of impregnated nanofiber mats was characterized by electronmicroscopy (SEM). Fourier transform infrared spectroscopy (FTIR) was used to analyze the chemical interaction of Nylon-6nanofiber mats and garlic sour. The antibacterial activities of impregnated garlic sour samples G-1, G-2 and G-3 wereevaluated against Escherichia coli and Staphylococcus aureus bacteria by using disc diffusion method. It was found that thegarlic sour has played a vital role for antibacterial activity. The nanofiber mats impregnated into garlic sour showed excellentantibacterial activity. It was observed that the antimicrobial effect for Escherichia coli and Staphylococcus aureus was morethan 99 %. The excellent hydrophobic property which revealed water contact angle was examined with dropping method andTGA were examined excellent thermal degradation rate of NY-6 NFS and impregnated garlic sour samples. NY-6 NFSshowed good mechanical strength according to ASTM D-638 standard. The obtained results indicate that the NY-6 NFSimpregnated in garlic sour is a promising antibacterial product that can be utilized as antibacterial wound dressing.
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