달 탐사선의 발사 요구조건 및 임무궤도 사례연구

석병석(Suk, Byong-suk),민승용(Min, Seung-yong),권재욱(Kwon, Jae-wook),김창균(Kim, Chang-kyoon),문상만(Moon, Sang-man),최수진(Choi, Su-jin),구철회(Koo, Cheol-hea),김인규(Kim, In-kyu),류동영(Ryu, Dong-young) 한국항공우주연구원 2015 항공우주산업기술동향 Vol.13 No.2

시험용 달 궤도선의 발사 요구조건 사전 분석 단계로 최근 외국에서 발사한 달 탐사선의 발사 요구조건을 분석하였다. 일반적으로 달 탐사선의 발사 요구조건은 달 임무 궤도를 결정하는 중요한 요소이며, 또한 지구, 달, 태양의 상대적인 운동으로 인해 임무궤도 요구조건을 만족하는 발사 가능 시간이 주기적으로 반복되는 경향이 있다. 분석 결과 설정된 발사 요구조건들로부터 달 궤도선의 주 임무가 달의 남/북극 지역의 광학 관측 임을 간접적으로 알 수 있었다. 향후 우리나라 달 궤도선 발사 요구 조건 설정에 본 논문이 도움이 되길 기대한다. In the preliminary study on launch window requirement for Korea Path-finder Lunar Orbiter(KPLO), the recent foreign lunar orbiter’s lauch window requirement was analyzed. Normally, the launch requirements depends on the mission orbit. Based on the relationship between Moon, Earth, and Sun, the launch time will be available periodically to meet requirements. In this paper, it is understood that the launch window requirements come from payload mission requirements to take picture each poles of Moon. This paper might be a practical example to derive KPLO launch requirements in the future.

白花蛇舌草 메탄올 抽出物의 抗腫瘍 效果 및 抗癌 棋戰에 關한 硏究

魯勳政,文九,文錫哉,元秦熹,文永昊,朴來佶 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

Objectives: This experimental study was carried out to evaluate the effects of aqueous and methanol extracts of Hedyotis diffusa which has long been used for cancer treatment in oriental medicines on the induction of apoptotic cell death in human lymphoid leukemia cell line, HL-60. Methods: Cells were treated with various concentrations (200 to 0.4㎍) and periods (6 to 30 hr) of H_2O and methanol extracts of Hedyotis diffusa. Then, cells were tested for viability by MTT assay. Cells wrere treated with 200㎍/ml of methanol extract fork various periods. Genomic DNA was isolated, separated, on 1.5% agarose gels, stained with ethidium bromide and visualized under UV light. Cells were treated with 200㎍/ml of each extract for 16hr.Then, cells were treated with various doses of each extract for 12 hr and 100㎍/ml of methanol extract for various periods. Lysate from the cells used to measure the activity of caspase-1 and-3 proteases by using fluorogenic peptide substrates including acetyl-YVAD-AMC and acetyl-DEVD-AMC, respectively, Cells were treated with 200㎍/ml of each extract for various periods. Cell lysates were immunoprecipated with anti-JNKl antibodies. The immune complex was reacted with 32^p-ATP and c-Jun as a substrate. The phosphotransferase activity of JNKI was measured by suing Phosphoimage analyzer (Fuji Co., Japan). Nuclear extracts were isolated and incubated with oligonucleotide probe of NF-kB was measured by using EMSA and visualized by PhosphoImage analyzer (Fuji Co, Japan). Cell lysates were prepared and analyzed by Western blotting with anti-Bc12 antibodies and anti-Bax antibodies. Cells were pretreated with various doses of methanol extract for 2 hr. Then, the extract was removed by centrifugation. Cells were resuspended with RPMI-1640 media containing 0.3% agarose, 10% FBS, overlayred onto bottom layer agarose and incubated at CO_2 incubator for 6 days. The number of colony was cunted under light microscopy (×100). Results: The death of HL_60 cells was markedly induced by the addition of methanol extract of Hedyotis diffusa in a dose and time-dependent manners. The apoptotic characteristic ladder pattern of DNA strand break was observed in death of HL_60 cells. In addition, it was shown nucleus chromatin condensation under Hoechst staining. Therefore, Hedyotis diffusa extract-induced death of HL-60 cells is mediated by apoptotic signaling processes. The activity of Caspaxe 3-like proteases remained in a basal level in HL-60 cells treated with aqueous extract of Hedyotis diffusa. However, it was markedly increased in HL-60 cells treated with methanol extract of Hedyotis diffusa. In addition, the phosphotransferase activity of JNKl was increased in HL-60 cells treated with methanol extract of Hedyotis diffusa. Furthermore, the activation of transcriptional activator, NF-kB was markedly induced by methanol extract of Hedyotis diffusa. Anti-apoptotic Bc12 was cleaved into 23Kda fragment by treatment of methanol extract of Hedyotis diffusa. However, expression of proapoptotic Bax protein was increased by treatment of methanol extract of Hedyotis diffusa in a time-dependent manner. Furthermore, methanol extract markedly inhibited the colony forming efficiency of HL-60 cells in semisolid agar culture. Conclusions: Above results suggest that methanol extract of Hedyotis diffusa induces the apoptotic death of human leukemic HL-60 cells via activations of Caspase-3 proteases, JNKI, transcriptional activator NF-κB, In addition, our results also suggest that methanol exthanol extract of Hedyotis diffusa reduces the malignant potential of HL-60 cells via down regulation of colony forming effciency through cleavage of Bc12 as well as induction of Bax.

일반논문 : 노자상이주(老子想爾注) 양생윤리 -양생의 시대적 변용이라는 관점에서-

정우진 ( Woo Jin Jung ),문석윤 ( Suk Yoon Moon ) 동양철학연구회 2013 東洋哲學硏究 Vol.75 No.-

본고는 『상이주』에 보이는 생명과 윤리의 논리를 양생윤리라는 개념으로 포착하고, 그것을 양생론의 시대적 변용이라는 관점에서 고찰한 연구의 결과물이다. 외척, 환관정치로 인해 생명이 피폐해지고 社의 권위가 흔들린 후한대의 상황은 개인적 차원에 머물러 있던 양생에 사회화를 요구했고, 그 결과 양생은 윤리와 결합하게 되었다. 감정을 중요한 생명의 단서로 생각하고, 감정의 유로를 생명의 소실로 보는 기존의 전통 윤리적 관념은, 양생윤리의 배경이 되었다. 『상이주』 양생윤리의 전모는 『正統道藏30冊』 543쪽에 실려 있는 ``道 德尊經戒``에 보인다. 도덕존경계에는 『도덕경』 등에 보이는 퇴양과 인순의 지혜가 담겨 있기 때문에, 『상이주』 도계는 지혜의 격언과 도덕규범 이 혼재된 것이었음을 알 수 있다. 이 점은 『상이주』가 『도덕경』 주석서 형태를 띠고 있다는 점, 또 『도덕경』의 가르침이 도덕규범으로 발전할 소지가 있었다는 점 등으로 설명될 수 있다. 『상이주』 양생윤리는 감정의 안정을 추구하던 전통적 양생론과 달랐다. 그러므로 마음의 안정을 지향하던 전통윤리와는 다른, 생명과 윤리를 연결하는 별도의 기제가 요구되었다. 『상이주』의 저자는 선악판단과 수명의 심판자인 天曹, 수명의 증감을 기록한 계약서라는 관념 그리고 尸解라는 독특한 죽음관을 적절히 이용해서 ``선악-천조의 관할-생명의 증감``이라는 논리를 만들었다. 이 배후에는 감정적 동요는 도덕적 악의 상태에 해당한다는 전통적 윤리관이 전제되어 있다. 결국 『상이주』 양생윤리는 감정의 안정을 추구하던 전통윤리, 그리고 전통윤리의 배후에 있던 생명과 윤리의 결합이라는 관념이 당시의 민중 신앙과 섞여 만들어진 양생론이자 민중종교 윤리였던 셈이다. Nurturing life is one of the most important thoughts in ancient china. Xiang Er Zhu is the bible of Wou Dou Mi Tu(五斗米徒). I investigated Xiang Er Zhu from the perspective of Nurturing Life in this treatise. Nurturing Life first shown in Zhuang Zi(莊子) and Guan Zi(管子) had developed through Qin Hin(秦漢) period and changed itself in accordance with the demand of age. This change can be told to be the development of Nurturing Life Theory. In post han period, Nurturing Life Theory had to fit itself into the age request, socialization. Nurturing Life Ethic in Xiang Er Zhu is the response to the request. China had some thoughts of the original form of Nurturing Life Ethic. Tai Ping Jing(太平經) is one of them. But the oldest model we can find would be in Guan Zi. In Guan Zi, we can find the thought that feeling stability cause health of mind and body. Nurturing Life in Xiang Er Zhu formed on the foundation of that thought. But it did not follow the same logic. It borrowed such concepts as Tai Yin(太陰), Tian Cao(天曹) from folk religion. Folk religion was familiar with the chinese and had the power to enforce moral behavior. People should keep Dao Jie(道誡) not to lessen his life by punishment of Tian Cao. But Zao Shen(조神) or San Shi(三尸) that report guilty of person to Tian Cao in Daoism Ethic is not in Xiang Er Zhu. Instead, Xiang Er Zhu proposed the technique of Shi Jie(尸解), revival from death. Nurturing Life Ethic in Xiang Er Zhu is folk religion ethic founded on the traditional ethic orienting feeling stability and the cohesion of life and ethic behind traditional ethic.

Ender정과 Knowles핀을 이용한 노인 대퇴골 전자부 골절의 치료

문명상,우영균,선두훈,남석현 최신의학사 1992 最新醫學 Vol.35 No.11

간호학생의 지역사회 간호 실습 경험

한진숙,심문숙 中央醫學社 1999 中央醫學 Vol.64 No.1

기독교 신앙과 윤리

文錫鎬 總神大學校 1995 總神大論叢 Vol.14 No.-

한국교회와 교회 공동체성의 회복 : 공동체로서의 교회를 향한 한국교회의 과제를 중심으로

문석호 總神大學校 1997 總神大論叢 Vol.16 No.-

염지 중 베이컨육의 특성 변화

문영덕,문윤희,곽석범 慶星大學校 1989 論文集 Vol.10 No.2

Cured becon meats were manufactured from bacon using dry curing method with varing levels of sodium chloride. To study the changes of moisture content, water activity, pH, salt concentration, extractability of proteins, SDS-PAGE and ATPase activity of protein were investigated during curing period at 3±1℃. During the process of curing, the moisture content and water activity in bacon meat decreased while the pH and salt concentration increased. Extractabilities of protein and SDS-PAGE shows that changes in extractability of water soluble protein are less noticeable while the extractability of salt soluble protein depended on curing period. These changes were rapid in the high level concentration of sodium chloride. The ATPase activity of myofibril from cured bacon with low level of salt concentration demonstrated a higher sensitivity to ionic strength than that of myofibril from cured bacon with high levels.

이방향 병용천공 발파공법의 수치해석적 분석

문홍득,송석은 진주산업대학교 건설기술연구소 1998 건설기술연구소보 Vol.1 No.-

This paper present an evaluation of new drilling and blasting method with two different drilling directions for pilot tunnel enlargement using numerical experiment. That is, three dimensional transient dynamic analysis was made to investigate the effect of the ground vibration when blasting was performed at same position using the equivalent single hole charge.

감잎의 영양학적 평가와 암예방 기능

문숙희 慶南專門大學 1997 論文集 Vol.25 No.1