http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Mohd Omar Abd Kadir (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Lim Fook-Hwa,Omar Abd Rasid,Abdul Wahab Mohd As’wad,Ganesan Vadamalai,Ghulam Kadir Ahmad Parveez,Wong Mui-Yun 한국식물생명공학회 2020 Plant biotechnology reports Vol.14 No.6
The global agricultural direct yield loss is estimated up to 40% and minimizing such loss is therefore crucial for future sustainability of global crop production. The discovery of RNA-mediated gene silencing mechanism has improved our understanding on gene expression and their regulation. The mechanism was later found applicable for controlling various plant pathogens. Recent discoveries indicated that plant small RNAs are involved in plant defence not only against viruses but also extended to other pathogens, such as insect pests and fungi. This fnding showed that RNA-mediated gene silencing is a conserved strategy employed by plant as a defence mechanism and will boost the application of RNA-mediated gene silencing to improve crop resistance against various pests and diseases. This review provided summaries of the application of RNA-mediated gene silencing in the plant protection against various pests and diseases including from nematodes, insects, fungi, and viruses. The strategies used and signifcant fndings were also discussed and this information can be considered for future planning of similar study. This review also provided the latest trends and potential applications of dsRNA via non-transgenic approach to control pests and diseases, namely spray-induced gene silencing. The advantages and disadvantages of application of RNA-mediated gene silencing in plant protection via transgenic and non-transgenic approaches were also discussed. The application of RNA-mediated gene silencing could ofer a promising solution for plant protection against pests and diseases.
-
Hussein M. Baharetha,Zeyad D. Nassar,Abdalrahim F. Aisha,Mohamed B. Khadeer Ahamed,Foaud Saleih R. Al-Suede,Mohd Omar Abd Kadir,Zhari Ismail,Amin Malik Shah Abdul Majid 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.12
Nigella sativa, commonly referred as black cumin, is a popular spice that has been used since the ancient Egyptians. It has traditionally been used for treatment of various human ailments ranging from fever to intestinal disturbances to cancer. This study investigated the apoptotic, antimetastatic, and anticancer activities of supercritical carbon dioxide (SCCO2) extracts of the seeds of N. sativa Linn. against estrogen-dependent human breast cancer cells (MCF-7). Twelve extracts were prepared from N. sativa seeds using the SC-CO2 extraction method by varying pressure and temperature. Extracts were analyzed using FTIR and UV-Vis spectrometry. Cytotoxicity of the extracts was evaluated on various human cancer and normal cell lines. Of the 12 extracts, 1 extract (A3) that was prepared at 60C and 2500 psi (*17.24 MPa) showed selective antiproliferative activity against MCF-7 cells with an IC50 of 53.34 – 2.15 lg/mL. Induction of apoptosis was confirmed by evaluating caspases activities and observing the cells under a scanning electron microscope. In vitro antimetastatic properties of A3 were investigated by colony formation, cell migration, and cell invasion assays. The elevated levels of caspases in A3 treated MCF-7 cells suggest that A3 is proapoptotic. Further nuclear condensation and fragmentation studies confirmed that A3 induces cytotoxicity through the apoptosis pathway. A3 also demonstrated remarkable inhibition in migration and invasion assays of MCF-7 cells at subcytotoxic concentrations. Thus, this study highlights the therapeutic potentials of SC-CO2 extract of N. sativa in targeting breast cancer.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
